Search Results - "Liu, Guanshu"

The role of imaging in 2019 novel coronavirus pneumonia (COVID-19) by Yang, Wenjing, Sirajuddin, Arlene, Zhang, Xiaochun, Liu, Guanshu, Teng, Zhongzhao, Zhao, Shihua, Lu, Minjie

“…Almost the entire world, not only China, is currently experiencing the outbreak of a novel coronavirus that causes respiratory disease, severe pneumonia, and…”
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Monitoring Tumor Response to Antivascular Therapy Using Non-Contrast Intravoxel Incoherent Motion Diffusion-Weighted MRI by Shi, Changzheng, Liu, Dexiang, Xiao, Zeyu, Zhang, Dong, Liu, Guanfu, Liu, Guanshu, Chen, Hanwei, Luo, Liangping

“…Antivascular therapy is a promising approach to the treatment of non-small cell lung cancer (NSCLC), where an imaging modality capable of longitudinally…”
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Nuts and bolts of chemical exchange saturation transfer MRI by Liu, Guanshu, Song, Xiaolei, Chan, Kannie W. Y., McMahon, Michael T.

“…Chemical exchange saturation transfer (CEST) has emerged as a novel MRI contrast mechanism that is well suited for molecular imaging studies. This new…”
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Sugar‐based biopolymers as novel imaging agents for molecular magnetic resonance imaging by Han, Zheng, Liu, Guanshu

“…Sugar‐based biopolymers have been recognized as attractive materials to develop macromolecule‐ and nanoparticle‐based cancer imaging and therapy. However,…”
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Hyperosmolar blood–brain barrier opening using intra-arterial injection of hyperosmotic mannitol in mice under real-time MRI guidance by Chu, Chengyan, Jablonska, Anna, Gao, Yue, Lan, Xiaoyan, Lesniak, Wojciech G., Liang, Yajie, Liu, Guanshu, Li, Shen, Magnus, Tim, Pearl, Monica, Janowski, Miroslaw, Walczak, Piotr

“…The blood–brain barrier (BBB) is the main obstacle to the effective delivery of therapeutic agents to the brain, compromising treatment efficacy for a variety…”
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Repurposing Clinical Agents for Chemical Exchange Saturation Transfer Magnetic Resonance Imaging: Current Status and Future Perspectives by Chen, Zelong, Han, Zheng, Liu, Guanshu

“…Molecular imaging is becoming an indispensable tool to pursue precision medicine. However, quickly translating newly developed magnetic resonance imaging (MRI)…”
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Natural D-glucose as a biodegradable MRI contrast agent for detecting cancer by Chan, Kannie W. Y., McMahon, Michael T., Kato, Yoshinori, Liu, Guanshu, Bulte, Jeff W. M., Bhujwalla, Zaver M., Artemov, Dmitri, van Zijl, Peter C. M.

“…Purpose: Modern imaging technologies such as CT, PET, SPECT, and MRI employ contrast agents to visualize the tumor microenvironment, providing information on…”
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Carbon Dots as a New Class of Diamagnetic Chemical Exchange Saturation Transfer (diaCEST) MRI Contrast Agents by Zhang, Jia, Yuan, Yue, Gao, Minling, Han, Zheng, Chu, Chengyan, Li, Yuguo, van Zijl, Peter C. M., Ying, Mingyao, Bulte, Jeff W. M., Liu, Guanshu

“…While carbon dots (C‐dots) have been extensively investigated pertaining to their fluorescent, phosphorescent, electrochemiluminescent, optoelectronic, and…”
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In Vivo Biomarker Imaging: Paving the Way for Precision Medicine by Liu, Guanshu, Yang, Xing, Zhou, Xin

“…In vivo bioimaging has become an indispensable tool in contemporary biomedical research and medicine [...]…”
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The effects of P2 segment of posterior cerebral artery to thalamus blood supply pattern on gait in cerebral small vessel disease: A 7 T MRI based study by Guo, Cen, Wang, Bei, Huo, Yajing, Shan, Lili, Qiao, Tianci, Yang, Zidong, Liu, Mingyuan, Wang, Yilin, Liu, Guanshu, Liu, Yajie, Wang, He, Han, Yan

“…Gait disturbance is a manifestation of cerebral small vessel disease (CSVD). The posterolateral thalamus (PL), whose blood is mainly supplied by the P2 segment…”
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Metabolic and vascular imaging markers for investigating Alzheimer's disease complicated by sleep fragmentation in mice by Han, Xiaoning, Liu, Guanshu, Lee, Sang Soo, Yang, Xiuli, Wu, Mark N, Lu, Hanzhang, Wei, Zhiliang

“…Sleep problem is a common complication of Alzheimer's disease (AD). Extensive preclinical studies have been performed to investigate the AD pathology. However,…”
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Frondoside A Inhibits an MYC-Driven Medulloblastoma Model Derived from Human-Induced Pluripotent Stem Cells by Xue, Yingchao, Fu, Yi, Zhao, Fenghong, Gui, Gege, Li, Yuguo, Rivero-Hinojosa, Samuel, Liu, Guanshu, Li, Yunqing, Xia, Shuli, Eberhart, Charles G, Ying, Mingyao

“…Medulloblastoma (MB) is the most common malignant pediatric brain tumor. MYC-driven MBs, commonly found in the group 3 MB, are aggressive and metastatic with…”
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Establishing the Lysine-rich Protein CEST Reporter Gene as a CEST MR Imaging Detector for Oncolytic Virotherapy by Farrar, Christian T, Buhrman, Jason S, Liu, Guanshu, Kleijn, Anne, Lamfers, Martine L M, McMahon, Michael T, Gilad, Assaf A, Fulci, Giulia

“…To (a) evaluate whether the lysine-rich protein (LRP) magnetic resonance (MR) imaging reporter gene can be engineered into G47Δ, a herpes simplex-derived…”
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Dextran-enhanced CEST MRI reveals the size effect of BBB dysfunction associated with neuroinflammation by Wang, Wenshen, Xu, Jiadi, Thomas, Aline, Liu, Guanshu

“…INTRODUCTION: The blood-brain barrier (BBB) is compromised in multiple central nervous system (CNS) disorders associated with neuroinflammation, including…”
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Genetically engineered human induced pluripotent stem cells for the production of brain-targeting extracellular vesicles by Tang, Fan, Dong, Tao, Zhou, Chengqian, Deng, Leon, Liu, Hans B, Wang, Wenshen, Liu, Guanshu, Ying, Mingyao, Li, Pan P

“…Extracellular vesicles (EVs) are cell-secreted membrane vesicles that have become a promising, natural nanoparticle system for delivering either naturally…”
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Imaging in Vivo Extracellular pH with a Single Paramagnetic Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agent by Liu, Guanshu, Li, Yuguo, Sheth, Vipul R., Pagel, Mark D.

“…The measurement of extracellular pH (pHe) has potential utility for cancer diagnoses and for assessing the therapeutic effects of pH-dependent therapies. A…”
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Real-Time MRI Guidance for Reproducible Hyperosmolar Opening of the Blood-Brain Barrier in Mice by Chu, Chengyan, Liu, Guanshu, Janowski, Miroslaw, Bulte, Jeff W M, Li, Shen, Pearl, Monica, Walczak, Piotr

“…The blood-brain barrier (BBB) prevents effective delivery of most therapeutic agents to the brain. Intra-arterial (IA) infusion of hyperosmotic mannitol has…”
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Aged fibroblast-derived extracellular vesicles promote angiogenesis in melanoma by Hüser, Laura, Chhabra, Yash, Gololobova, Olesia, Wang, Vania, Liu, Guanshu, Dixit, Agrani, Rocha, Murilo Ramos, Harper, Elizabeth I., Fane, Mitchell E., Marino-Bravante, Gloria E., Zabransky, Daniel J., Cai, Kathy Q., Utikal, Jochen, Slusher, Barbara S., Walston, Jeremy, Lipson, Evan J., Witwer, Kenneth W., Weeraratna, Ashani T.

“…Advancing age is a negative prognostic factor for cutaneous melanoma. However, the role of extracellular vesicles (EVs) within the melanoma tumor…”
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Label-free CEST MRI Detection of Citicoline-Liposome Drug Delivery in Ischemic Stroke by Liu, Huanling, Jablonska, Anna, Li, Yuguo, Cao, Suyi, Liu, Dexiang, Chen, Hanwei, Van Zijl, Peter Cm, Bulte, Jeff W M, Janowski, Miroslaw, Walczak, Piotr, Liu, Guanshu

“…Citicoline (CDPC) is a natural supplement with well-documented neuroprotective effects in the treatment of neurodegenerative diseases. In the present study, we…”
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In vivo multicolor molecular MR imaging using diamagnetic chemical exchange saturation transfer liposomes by Liu, Guanshu, Moake, Matthew, Har-el, Yah-el, Long, Chris M., Chan, Kannie W.Y., Cardona, Amanda, Jamil, Muksit, Walczak, Piotr, Gilad, Assaf A., Sgouros, George, van Zijl, Peter C.M., Bulte, Jeff W.M., McMahon, Michael T.

“…A variety of (super)paramagnetic contrast agents are available for enhanced MR visualization of specific tissues, cells, or molecules. To develop alternative…”
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