Search Results - "Liu, Gengtao"

P-glycoprotein mediated efflux limits the transport of the novel anti-Parkinson's disease candidate drug FLZ across the physiological and PD pathological in vitro BBB models by Liu, Qian, Hou, Jinfeng, Chen, Xiaoguang, Liu, Gengtao, Zhang, Dan, Sun, Hua, Zhang, Jinlan

“…FLZ, a novel anti-Parkinson's disease (PD) candidate drug, has shown poor blood-brain barrier (BBB) penetration based on the pharmacokinetic study using rat…”
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Anticonvulsant activity of B2, an adenosine analog, on chemical convulsant-induced seizures by Li, Min, Kang, Ruixia, Shi, Jiangong, Liu, Gengtao, Zhang, Jianjun

“…Epilepsy is a chronic neurological disorder characterized by recurrent seizures. However, approximately one-third of epilepsy patients still suffer from…”
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H1, a novel derivative of tetrandrine reverse P-glycoprotein-mediated multidrug resistance by inhibiting transport function and expression of P-glycoprotein by Wei, Ning, Sun, Hua, Wang, Fengpeng, Liu, Gengtao

“…Purpose H1 is a novel derivative of tetrandrine (Tet). Here we investigate the ability of H1 to reverse P-glycoprotein (Pgp)-mediated multidrug resistance…”
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A Novel Cyclic Squamosamide Analogue Compound FLZ Improves Memory Impairment in Artificial Senescence Mice Induced by Chronic Injection of D‐Galactose and NaNO2 by Fang, Fang, Liu, Gengtao

“…:  The aim of the present study was to access the protective effect of a novel synthesized squamosamide cyclic analogue, compound FLZ, on memory impairment in…”
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Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity by Zhang, Dan, Hu, Xiaoming, Wei, Sung-Jen, Liu, Jie, Gao, Huiming, Qian, Li, Wilson, Belinda, Liu, Gengtao, Hong, Jau-Shyong

“…Inflammation plays an important role in the pathogenesis of Parkinson's disease (PD) through over-activation of microglia, which consequently causes the…”
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Isorhapontigenin and resveratrol suppress oxLDL-induced proliferation and activation of ERK1/2 mitogen-activated protein kinases of bovine aortic smooth muscle cells by Liu, Yinglin, Liu, Gengtao

“…The objective of our study was to compare the inhibitory effect of isorhapontigenin (ISO) and resveratrol, two natural antioxidants, on oxidized low-density…”
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Reversal of multidrug resistance of cancer through inhibition of P-glycoprotein by 5-bromotetrandrine by JING JIN, WANG, Feng-Peng, HUAILING WEI, GENGTAO LIU

“…The present study aimed to evaluate the MDR reversal activity of bromotetrandrine (BrTet), a bromized derivative of tetrandrine (Tet), in vitro and in vivo…”
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Coeloglossum viride var. bracteatum extract attenuates d-galactose and NaNO2 induced memory impairment in mice by Zhang, Dan, Liu, Gengtao, Shi, Jiangong, Zhang, Jianjun

“…The aim is to study the neuroprotective effects of CE, a special extract from Coeloglossum viride (L.) Hartm. var. bracteatum (Willd.), on memory deficits in…”
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Improvement of high-fat-diet-induced metabolic syndrome by a compound from Balanophora polyandra Griff in mice by Tao, Rongya, Ye, Fei, He, Yibo, Tian, Jinying, Liu, Gengtao, Ji, Tengfei, Su, Yalun

“…This study was to explore the effects of a compound (BPG) from Balanophora polyandra Griff on metabolic syndrome in mice. The animal models, developed obesity,…”
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Effect of diphenyl dimethyl bicarboxylate on concanavalin A-induced liver injury in mice by Gao, Mei, Zhang, Jianjun, Liu, Gengtao

“…: Diphenyl dimethyl bicarboxylate (DDB) is a hepatoprotectant and used in the treatment of chronic viral hepatitis patients in China. The aim of the present…”
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Modulating expression of brain heat shock proteins by estrogen in ovariectomized mice model of aging by Hou, Yan, Wei, Huailing, Luo, Yuan, Liu, Gengtao

“…Heat shock proteins (HSPs) serve as molecular chaperones and endogenous cytoprotective factors. Two of the well-studied HSPs, HSP70, and HSP27 can be…”
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Sedative and hypnotic activity of N(6)-(3-methoxyl-4-hydroxybenzyl) adenine riboside (B2), an adenosine analog by Li, Min, Kang, Ruixia, Jia, Shaobo, Shi, Jiangong, Liu, GengTao, Zhang, JianJun

“…N(6)-(3-methoxyl-4-hydroxybenzyl) adenine riboside (B2) is an N(6)-substitued adenosine analog. Previous studies have shown that B2 binds to the adenosine A1…”
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Sedative and hypnotic activity of N6-(3-methoxyl-4-hydroxybenzyl) adenine riboside (B2), an adenosine analog by Li, Min, Kang, Ruixia, Jia, Shaobo, Shi, Jiangong, Liu, GengTao, Zhang, JianJun

“…N6-(3-methoxyl-4-hydroxybenzyl) adenine riboside (B2) is an N6-substitued adenosine analog. Previous studies have shown that B2 binds to the adenosine A1 and…”
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A Novel Cyclic Squamosamide Analogue Compound FLZ Improves Memory Impairment in Artificial Senescence Mice Induced by Chronic Injection of D-Galactose and NaNO sub(2) by Fang, Fang, Liu, Gengtao

“…The aim of the present study was to access the protective effect of a novel synthesized squamosamide cyclic analogue, compound FLZ, on memory impairment in…”
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A Novel Cyclic Squamosamide Analogue Compound FLZ Improves Memory Impairment in Artificial Senescence Mice Induced by Chronic Injection of D‐Galactose and NaNO 2 by Fang, Fang, Liu, Gengtao

“…The aim of the present study was to access the protective effect of a novel synthesized squamosamide cyclic analogue, compound FLZ, on memory impairment in…”
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Dactylorhin B reduces toxic effects of beta-amyloid fragment (25-35) on neuron cells and isolated rat brain mitochondria by Zhang, Dan, Zhang, Yi, Liu, Gengtao, Zhang, Jianjun

“…beta-amyloid is strongly implicated in Alzheimer's pathology, and mitochondria play an important role in neurodegenerative disorders. Dactylorhin B [short for…”
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Effectiveness of the analogue of natural Schisandrin C (HpPro) in treatment of liver diseases: an experience in Indonesian patients by Akbar, N, Tahir, R A, Santoso, W D, Soemarno, Sumaryono, Noer, H M, Liu, G

“…To determine the effect of dimethyl-4,4'-dimethoxy-5,6, 5',6-dimethylene dioxybiphenyl-2,2'-dicarboxylate (HpPro) on patients with acute and chronic liver…”
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Scavenging effects on active oxygen radicals by schizandrins with different structures and configurations by Li, X J, Zhao, B L, Liu, G T, Xin, W J

“…We have studied the scavenging effects of different structures and configurations of schizandrins isolated from Fructus Schizandrae, a traditional Chinese…”
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The anti-hepatitis drug DDB chemosensitizes multidrug resistant cancer cells in vitro and in vivo by inhibiting P-gp and enhancing apoptosis by Jin, Jing, Sun, Hua, Wei, Huailing, Liu, Gengtao

“…DDB (dimethyl-4,4'-dimethoxy-5,6,5'6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate) is a synthetic hepatoprotectant which has been widely used to treat chronic…”
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The study of innate drug resistance of human hepatocellular carcinoma Bel7402 cell line by Huang, Min, Liu, GengTao

“…The innate drug resistance of human hepatocellular carcinoma (HCC) Bel7402 cell line was studied in vitro. MTT assay showed that Bel7402 cells were innately…”
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