Search Results - "Liu, Fuyou"

Mitochondrial dynamics: regulatory mechanisms and emerging role in renal pathophysiology by Zhan, Ming, Brooks, Craig, Liu, Fuyou, Sun, Lin, Dong, Zheng

“…Mitochondria are a class of dynamic organelles that constantly undergo fission and fusion. Mitochondrial dynamics is governed by a complex molecular machinery…”
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Mitochondrial dysregulation and protection in cisplatin nephrotoxicity by Yang, Yuan, Liu, Hong, Liu, Fuyou, Dong, Zheng

“…Nephrotoxicity is a major side effect of cisplatin in chemotherapy. Pathologically, cisplatin nephrotoxicity is characterized by cell injury and death in renal…”
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Prevalence of chronic kidney disease in China: a cross-sectional survey by Zhang, Luxia, MD, Wang, Fang, MD, Wang, Li, Prof, Wang, Wenke, Prof, Liu, Bicheng, Prof, Liu, Jian, Prof, Chen, Menghua, Prof, He, Qiang, Prof, Liao, Yunhua, Prof, Yu, Xueqing, Prof, Chen, Nan, Prof, Zhang, Jian-e, Prof, Hu, Zhao, Prof, Liu, Fuyou, Prof, Hong, Daqing, MD, Ma, Lijie, MD, Liu, Hong, MD, Zhou, Xiaoling, MD, Chen, Jianghua, MD, Pan, Ling, MD, Chen, Wei, MD, Wang, Weiming, MD, Li, Xiaomei, Prof, Wang, Haiyan, Prof

“…Summary Background The prevalence of chronic kidney disease is high in developing countries. However, no national survey of chronic kidney disease has been…”
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Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis by Han, Yachun, Xu, Xiaoxuan, Tang, Chengyuan, Gao, Peng, Chen, Xianghui, Xiong, Xiaofen, Yang, Ming, Yang, Shikun, Zhu, Xuejing, Yuan, Shuguang, Liu, Fuyou, Xiao, Li, Kanwar, Yashpal S., Sun, Lin

“…NLRP3/IL-1β activation via thioredoxin (TRX)/thioredoxin-interacting protein (TXNIP) following mitochondria ROS (mtROS) overproduction plays a key role in…”
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The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1 by Xiao, Li, Xu, Xiaoxuan, Zhang, Fan, Wang, Ming, Xu, Yan, Tang, Dan, Wang, Jiahui, Qin, Yan, Liu, Yu, Tang, Chengyuan, He, Liyu, Greka, Anna, Zhou, Zhiguang, Liu, Fuyou, Dong, Zheng, Sun, Lin

“…Mitochondria play a crucial role in tubular injury in diabetic kidney disease (DKD). MitoQ is a mitochondria-targeted antioxidant that exerts protective…”
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PINK1-PRKN/PARK2 pathway of mitophagy is activated to protect against renal ischemia-reperfusion injury by Tang, Chengyuan, Han, Hailong, Yan, Mingjuan, Zhu, Shiyao, Liu, Jing, Liu, Zhiwen, He, Liyu, Tan, Jieqiong, Liu, Yu, Liu, Hong, Sun, Lin, Duan, Shaobin, Peng, Youming, Liu, Fuyou, Yin, Xiao-Ming, Zhang, Zhuohua, Dong, Zheng

“…Damaged or dysfunctional mitochondria are toxic to the cell by producing reactive oxygen species and releasing cell death factors. Therefore, timely removal of…”
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TLR4/NF-κB Signaling Induces GSDMD-Related Pyroptosis in Tubular Cells in Diabetic Kidney Disease by Wang, Youliang, Zhu, Xuejing, Yuan, Shuguang, Wen, Si, Liu, Xuemei, Wang, Chang, Qu, Zhong, Li, Jun, Liu, Hong, Sun, Lin, Liu, Fuyou

“…Gasdermin D (GSDMD) has been proven to be a key protein in the activation of pyroptosis. Pyroptosis of renal tubular epithelial cells contributes to the…”
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Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts by Chen, Guochun, Chen, Huihui, Wang, Chang, Peng, Youming, Sun, Lin, Liu, Hong, Liu, Fuyou

“…Interstitial fibrosis is an inevitable outcome of all kinds of progressive chronic kidney disease (CKD). Emerging data indicate that rapamycin can ameliorate…”
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Glycoprotein non-metastatic melanoma protein b (Gpnmb) is highly expressed in macrophages of acute injured kidney and promotes M2 macrophages polarization by Zhou, Letian, Zhuo, Hui, Ouyang, Huiyu, Liu, Yexin, Yuan, Fang, Sun, Lin, Liu, Fuyou, Liu, Hong

“…•Gpnmb is upregulated in macrophages from AKI.•Gpnmb inhibits the polarization of M1 BMMφ.•Gpnmb promotes the polarization of M2 BMMφ. Acute kidney injury…”
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Autophagy is activated to protect against podocyte injury in adriamycin-induced nephropathy by Yi, Mixuan, Zhang, Lei, Liu, Yu, Livingston, Man J, Chen, Jian-Kang, Nahman, Jr, N Stanley, Liu, Fuyou, Dong, Zheng

“…Podocytes are highly differentiated epithelial cells wrapping glomerular capillaries to form the filtration barrier in kidneys. As such, podocyte injury or…”
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Rap1 Ameliorates Renal Tubular Injury in Diabetic Nephropathy by LI XIAO, XUEJING ZHU, KANWAR, Yashpal S, LIN SUN, SHIKUN YANG, FUYOU LIU, ZHIGUANG ZHOU, MING ZHAN, PING XIE, DONGSHAN ZHANG, JUN LI, PANAI SONG

“…Rap1b ameliorates high glucose (HG)-induced mitochondrial dysfunction in tubular cells. However, its role and precise mechanism in diabetic nephropathy (DN) in…”
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Identification of transcription factors related to diabetic tubulointerstitial injury by Liu, Jialu, Duan, Guangzhong, Yang, Wenxia, Zhang, Shumin, Liu, Fuyou, Peng, Youming, Sun, Lin, Liu, Yu, Xiao, Li

“…Diabetic nephropathy (DN) is a main cause of chronic renal failure. Despite decades of extensive study, the molecular mechanisms underlying diabetic…”
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Variable Stiffness Electroadhesion and Compliant Electroadhesive Grippers by Chen, Rui, Zhang, Zhuo, Guo, Jianglong, Liu, Fuyou, Leng, Jinsong, Rossiter, Jonathan

“…Soft adhesion is capable of attaching and bonding to rough surfaces and gripping nonplanar materials. It is preferable for material handling applications where…”
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Transition of mesothelial cell to fibroblast in peritoneal dialysis: EMT, stem cell or bystander? by Liu, Yu, Dong, Zheng, Liu, Hong, Zhu, Jiefu, Liu, Fuyou, Chen, Guochun

“…Long-term peritoneal dialysis (PD) can lead to fibrotic changes in the peritoneum, characterized by loss of mesothelial cells (MCs) and thickening of the…”
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ATF5 regulates tubulointerstitial injury in diabetic kidney disease via mitochondrial unfolded protein response by Liu, Yifei, Zhang, Lei, Zhang, Shumin, Liu, Jialu, Li, Xiaohui, Yang, Kexin, Yang, Danyi, Liu, Yu, Sun, Lin, Liu, Fuyou, Xiao, Li

“…Mitochondrial quality control (MQC) plays a critical role in the progression of tubulointerstitial injury in diabetic kidney disease (DKD). The mitochondrial…”
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Predictive value of sub classification of focal segmental glomerular sclerosis in Oxford classification of IgA nephropathy by Yu, Fang, Zhu, Xuejing, Yuan, Shuguang, Chen, Xiaojun, Li, Zheng, Qu, Zhong, Liu, Hong, Sun, Lin, Liu, Fuyou

“…The Oxford classification of IgA nephropathy (IgAN) was revised in 2016 which lacked sufficient evidence for prognostic value of subclassification of focal…”
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Bowman's capsule rupture and the Oxford MEST-C score in adult patients with Immunoglobulin a vasculitis nephritis: a single center experience by Zhao, Qing, Duan, Tongyue, Chen, Anqun, He, Liyu, Liu, Hong, Yuan, Shuguang, Tang, Chengyuan, Liu, Yinghong, Liu, Yu, Liu, Fuyou, Xiao, Li, Zhu, Xuejing, Sun, Lin

“…BCR was associated with clinical manifestations and pathological changes in patients with IgAV-N, particularly crescents. The ISKDC classification was related…”
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Association between albumin-to-globulin ratio and long-term mortality in patients with chronic kidney disease: a cohort study by Zeng, Mengru, Liu, Yu, Liu, Fuyou, Peng, Youming, Sun, Lin, Xiao, Li

“…Purpose To examine whether albumin-to-globulin ratio (AGR) is correlated with long-term mortality in patients with chronic kidney disease (CKD), we performed…”
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Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy by Yuan, Fang, Kolb, Ryan, Pandey, Gaurav, Li, Wei, Sun, Lin, Liu, Fuyou, Sutterwala, Fayyaz S, Liu, Yinghong, Zhang, Weizhou

“…Diabetic nephropathy (DN) is the leading cause of end-stage kidney disease worldwide but current treatments remain suboptimal. The role of inflammation in DN…”
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Tubular atrophy/interstitial fibrosis scores of Oxford classification combinded with proteinuria level at biopsy provides earlier risk prediction in lgA nephropathy by Zhu, Xuejing, Li, Huiqiong, Liu, Yexin, You, Jing, Qu, Zhong, Yuan, Shuguang, Peng, Youming, Liu, Fuyou, Liu, Hong

“…The predictive effect of combining MEST with clinical data at biopsy on renal survival outcomes has not been investigated in patients with IgA nephropathy…”
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