Search Results - "Liu, Frances D."
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1
Chemical Transformations of Nanosilver in Biological Environments
Published in ACS nano (27-11-2012)“…The widespread use of silver nanoparticles (Ag-NPs) in consumer and medical products provides strong motivation for a careful assessment of their environmental…”
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Improving hematopoietic recovery through modeling and modulation of the mesenchymal stromal cell secretome
Published in Stem cell research & therapy (24-10-2018)“…Efficient and sustained hematopoietic recovery after hematopoietic stem cell or bone marrow transplantation is supported by paracrine signaling from specific…”
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SENTI-101, a Preparation of Mesenchymal Stromal Cells Engineered to Express IL12 and IL21, Induces Localized and Durable Antitumor Immunity in Preclinical Models of Peritoneal Solid Tumors
Published in Molecular cancer therapeutics (01-09-2021)“…Advanced peritoneal carcinomatosis including high-grade ovarian cancer has poor prognoses and a poor response rate to current checkpoint inhibitor…”
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Material Viscoelastic Properties Modulate the Mesenchymal Stem Cell Secretome for Applications in Hematopoietic Recovery
Published in ACS biomaterials science & engineering (11-12-2017)“…Human mesenchymal stem cells (MSCs) exhibit morphological and phenotypic changes that correlate with mechanical cues presented by the substratum material to…”
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430 Smart sensor promoters drive state-specific gene circuits to convert immunosuppressive macrophages into an anti-tumor phenotype
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundImmunosuppressive signaling from myeloid cells and macrophages in tumor microenvironments hampers the clinical efficacy of immunotherapies…”
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Abstract 4246: SENTI-101, a novel genetically modified allogeneic cell product expressing IL12 and IL21, elicits a tumor-localized, robust, and multimodal immune response in preclinical models of solid tumors
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract While immunotherapies based on single recombinant cytokines such as IL12 and IL21 have shown great promise in preclinical models of solid tumors,…”
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