Search Results - "Liu, Fengjiang"
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Structure of the RNA-dependent RNA polymerase from COVID-19 virus
Published in Science (American Association for the Advancement of Science) (15-05-2020)“…A novel coronavirus [severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2)] outbreak has caused a global coronavirus disease 2019 (COVID-19) pandemic,…”
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Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
Published in Science (American Association for the Advancement of Science) (19-06-2020)“…SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the etiological agent responsible for the global COVID-19 (coronavirus disease 2019) outbreak…”
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Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase
Published in Cell (23-07-2020)“…Nucleotide analog inhibitors, including broad-spectrum remdesivir and favipiravir, have shown promise in in vitro assays and some clinical studies for COVID-19…”
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Bandgap control in two-dimensional semiconductors via coherent doping of plasmonic hot electrons
Published in Nature communications (15-07-2021)“…Bandgap control is of central importance for semiconductor technologies. The traditional means of control is to dope the lattice chemically, electrically or…”
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Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels
Published in Nature communications (30-07-2021)“…Cytochromes bd are ubiquitous amongst prokaryotes including many human-pathogenic bacteria. Such complexes are targets for the development of antimicrobial…”
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Potent SARS-CoV-2 neutralizing antibodies with protective efficacy against newly emerged mutational variants
Published in Nature communications (02-11-2021)“…Accumulating mutations in the SARS-CoV-2 Spike (S) protein can increase the possibility of immune escape, challenging the present COVID-19 prophylaxis and…”
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Micro-scale opto-thermo-mechanical actuation in the dry adhesive regime
Published in Light, science & applications (22-09-2021)“…Realizing optical manipulation of microscopic objects is crucial in the research fields of life science, condensed matter physics, and physical chemistry. In…”
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An adeno-associated virus variant enabling efficient ocular-directed gene delivery across species
Published in Nature communications (06-05-2024)“…Recombinant adeno-associated viruses (rAAVs) have emerged as promising gene therapy vectors due to their proven efficacy and safety in clinical applications…”
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Discovery and characterization of potent pan-variant SARS-CoV-2 neutralizing antibodies from individuals with Omicron breakthrough infection
Published in Nature communications (15-06-2023)“…The SARS-CoV-2 Omicron variant evades most currently approved neutralizing antibodies (nAbs) and caused drastic decrease of plasma neutralizing activity…”
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Serum amyloid A1 exacerbates hepatic steatosis via TLR4-mediated NF-κB signaling pathway
Published in Molecular metabolism (Germany) (01-05-2022)“…Chronic inflammatory response plays a prominent role in obesity-related nonalcoholic fatty liver disease (NAFLD). However, the intrahepatic triggering…”
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Enhanced nonlinearity for filamentation in gold-nanoparticle-doped water
Published in Chinese optics letters (10-03-2019)Get full text
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12
Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
Published in Nature (London) (11-06-2020)“…A new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the aetiological agent responsible for the 2019–2020 viral…”
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13
Repetition rate stabilization of an erbium-doped all-fiber laser via opto-mechanical control of the intracavity group velocity
Published in Applied physics letters (19-01-2015)“…We present a method for stabilizing the repetition rate of an erbium-doped all-fiber laser by inserting an electronic polarization controller (EPC) in the…”
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Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein
Published in Signal transduction and targeted therapy (10-06-2024)“…Respiratory syncytial virus (RSV) is the major cause of bronchiolitis and pneumonia in young children and the elderly. There are currently no approved…”
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‘Plug-and-play’ plasmonic metafibers for ultrafast fibre lasers
Published in Light: advanced manufacturing (2022)“…Metafibers expand the functionalities of conventional optical fibres to unprecedented nanoscale light manipulations by integrating metasurfaces on the fibre…”
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Enhancing MPS Signal by Bipolar Pulse Excitation and Interference of Reflection Wave
Published in IEEE transactions on instrumentation and measurement (01-10-2014)“…To enhance the signal intensity of magnetostrictive position sensor (MPS), a new method of bipolar pulse excitation (BPE), and a new structure of single-end…”
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Enhanced filament ablation of metals based on plasma grating in air
Published in AIP advances (01-09-2015)“…We demonstrate efficient ablation of metals with filamentary plasma grating generated by two intense blue femtosecond filaments and a third focused infrared…”
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18
Structure of M pro from SARS-CoV-2 and discovery of its inhibitors
Published in Nature (London) (01-06-2020)“…A new coronavirus, known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is the aetiological agent responsible for the 2019-2020 viral…”
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Evaluation of levamlodipine benzenesulfonate compound I for embryo-fetal developmental toxicity in SD rats and genotoxicity
Published in Reproductive toxicology (Elmsford, N.Y.) (01-10-2024)“…In the present study, the effects of levamlodipine benzenesulfonate on the development of fertile Sprague-Dawley (SD) rats, their embryos, and littermates were…”
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Bifacial omnidirectional and band-tunable light absorption in free-standing core–shell resonators
Published in Applied physics letters (02-05-2022)“…Effective optical absorption is highly desirable for numerous applications in energy harvesting and optoelectronics. Bifacial absorbers can significantly…”
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