Search Results - "Liu, Feng Chun"
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1
Sepsis heterogeneity
Published in World journal of pediatrics : WJP (01-10-2023)“…Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection, with extremely high mortality. Notably, sepsis…”
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Microglial MT1 activation inhibits LPS‐induced neuroinflammation via regulation of metabolic reprogramming
Published in Aging cell (01-06-2021)“…Parkinson’s disease (PD) is one of the most common neurodegenerative diseases. Although its pathogenesis remains unclear, a number of studies indicate that…”
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3
α‐synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease
Published in Aging cell (01-12-2021)“…The cell‐to‐cell transfer of α‐synuclein (α‐Syn) greatly contributes to Parkinson's disease (PD) pathogenesis and underlies the spread of α‐Syn pathology…”
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BMAL1 regulation of microglia‐mediated neuroinflammation in MPTP‐induced Parkinson's disease mouse model
Published in The FASEB journal (01-05-2020)“…Dysfunction of the circadian rhythm is one of most common nonmotor symptoms in Parkinson's disease (PD), but the molecular role of the circadian rhythm in PD…”
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Hydrogen sulfide protects blood–brain barrier integrity following cerebral ischemia
Published in Journal of neurochemistry (01-06-2014)“…By using two structurally unrelated hydrogen sulfide (H2S) donors 5‐(4‐methoxyphenyl) ‐3H‐1, 2‐dithiole‐3‐thione (ADT) and sodium hydrosulfide (NaHS), this…”
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6
Advances of Zebrafish in Neurodegenerative Disease: From Models to Drug Discovery
Published in Frontiers in pharmacology (14-07-2021)“…Neurodegenerative disease (NDD), including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis, are characterized by the progressive…”
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Roles of protein post-translational modifications in glucose and lipid metabolism: mechanisms and perspectives
Published in Molecular medicine (Cambridge, Mass.) (06-07-2023)“…The metabolism of glucose and lipids is essential for energy production in the body, and dysregulation of the metabolic pathways of these molecules is…”
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Application and interpretation of current autophagy inhibitors and activators
Published in Acta pharmacologica Sinica (01-05-2013)“…is the major intracellular degradation system, by which cytoplasmic materials are delivered to and degraded in the lyso- some. As a quality control mechanism…”
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Free thyroxine, brain frailty and clock drawing test performance in patients with acute minor stroke or transient ischaemic attack
Published in Clinical endocrinology (Oxford) (01-02-2022)“…Objective Thyroid dysfunction is associated with an elevated risk of cognitive decline, but the mechanism underlying this relationship is elusive. In this…”
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10
Overexpression of miR-150-5p Alleviates Apoptosis in Sepsis-Induced Myocardial Depression
Published in BioMed research international (2020)“…Sepsis-induced myocardial depression has high mortality and is very common in intensive care units. Previous studies have found that microRNAs play an…”
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Clinical and electroencephalogram characteristics of methylmalonic acidemia with MMACHC and MUT gene mutations
Published in BMC pediatrics (14-02-2024)“…This study investigated the clinical, imaging, and electroencephalogram (EEG) characteristics of methylmalonic acidemia (MMA) with nervous system damage as the…”
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12
Unraveling the interplay between dyskinesia and overactive bladder symptoms in Parkinson's disease: a comprehensive cohort study based on the long-term follow-up database of Parkinson's disease
Published in BMC neurology (12-03-2024)“…Overactive bladder (OAB) and dyskinesia are frequent complications in patients with Parkinson's disease (PD). However, the correlation between OAB and…”
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13
Melatonin alleviates lipopolysaccharide‐compromised integrity of blood–brain barrier through activating AMP‐activated protein kinase in old mice
Published in Aging cell (01-04-2017)“…Summary Blood–brain barrier (BBB) dysfunction is considered to be an early event in the pathogenesis of a variety of neurological diseases in old patients, and…”
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14
Changes in Olfactory Bulb Volume in Parkinson's Disease: A Systematic Review and Meta-Analysis
Published in PloS one (22-02-2016)“…The changes in olfactory bulb (OB) volume in Parkinson's disease (PD) patients have not yet been comprehensively evaluated. The purpose of this meta-analysis…”
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15
A Critical Role of Autophagy in Regulating Microglia Polarization in Neurodegeneration
Published in Frontiers in aging neuroscience (20-11-2018)“…Neuroinflammation and autophagy dysfunction are closely related to the development of neurodegeneration such as Parkinson's disease (PD). However, the role of…”
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Cellular and molecular biology of sirtuins in cardiovascular disease
Published in Biomedicine & pharmacotherapy (01-08-2023)“…Sirtuins (SIRTs) are a nicotinic adenine dinucleotide (+) -dependent histone deacetylase that regulates critical signaling pathways in prokaryotes and…”
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Restless legs syndrome and perceived olfactory and taste dysfunction: A community‐based study
Published in European journal of neurology (01-08-2021)“…Background and purpose Restless legs syndrome (RLS) has been suggested as a prodromal symptom of Parkinson disease (PD). Olfactory or taste dysfunction can…”
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18
Prognostic Significance of Blood Urea Nitrogen in Acute Ischemic Stroke
Published in Circulation Journal (2018)“…Background:Prior studies have shown an association between high blood urea nitrogen (BUN) and an elevated risk of mortality in heart failure patients, but data…”
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Relationship between 25‐Hydroxyvitamin D, bone density, and Parkinson’s disease symptoms
Published in Acta neurologica Scandinavica (01-10-2019)“…Objectives Vitamin D deficiency is widespread in patients with Parkinson's disease (PD). Our aim was to determine whether serum vitamin D levels correlated…”
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Targeting epigenetic and post-translational modifications regulating pyroptosis for the treatment of inflammatory diseases
Published in Pharmacological research (01-05-2024)“…Inflammatory diseases, including infectious diseases, diabetes-related diseases, arthritis-related diseases, neurological diseases, digestive diseases, and…”
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