Search Results - "Liu, Erdong"
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1
Potential of Staphylea holocarpa Wood for Renewable Bioenergy
Published in Molecules (Basel, Switzerland) (30-12-2022)“…Energy is indispensable in human life and social development, but this has led to an overconsumption of non-renewable energy. Sustainable energy is needed to…”
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2
Efficacy and long-term safety of CRISPR/Cas9 genome editing in the SOD1-linked mouse models of ALS
Published in Communications biology (25-03-2021)“…CRISPR/Cas9-mediated genome editing provides potential for therapeutic development. Efficacy and long-term safety represent major concerns that remain to be…”
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3
Hyperactive Intracellular Calcium Signaling Associated with Localized Mitochondrial Defects in Skeletal Muscle of an Animal Model of Amyotrophic Lateral Sclerosis
Published in The Journal of biological chemistry (01-01-2010)“…Amyotrophic lateral sclerosis (ALS) is a fatal neuromuscular disorder characterized by degeneration of motor neurons and atrophy of skeletal muscle. Mutations…”
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4
Patient‐derived organoids for personalized gallbladder cancer modelling and drug screening
Published in Clinical and translational medicine (01-01-2022)“…Background Gallbladder carcinoma (GBC) is a relatively rare but highly aggressive cancer with late clinical detection and a poor prognosis. However, the lack…”
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5
Dendritic spinopathy in transgenic mice expressing ALS/dementia-linked mutant UBQLN2
Published in Proceedings of the National Academy of Sciences - PNAS (07-10-2014)“…Mutations in the gene encoding ubiquilin2 ( UBQLN2 ) cause amyotrophic lateral sclerosis (ALS), frontotemporal type of dementia, or both. However, the…”
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Conversion to the Amyotrophic Lateral Sclerosis Phenotype Is Associated with Intermolecular Linked Insoluble Aggregates of SOD1 in Mitochondria
Published in Proceedings of the National Academy of Sciences - PNAS (02-05-2006)“…Twenty percent of the familial form of amyotrophic lateral sclerosis (ALS) is caused by mutations in the Cu, Zn-superoxide dismutase gene (SOD1) through the…”
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7
Single-cell dissection of remodeled inflammatory ecosystem in primary and metastatic gallbladder carcinoma
Published in Cell discovery (05-10-2022)“…Gallbladder carcinoma (GBC) is the most common biliary tract malignancy with the lowest survival rate, primarily arising from chronic inflammation. To better…”
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Novel transketolase inhibitor oroxylin A suppresses the non‐oxidative pentose phosphate pathway and hepatocellular carcinoma tumour growth in mice and patient‐derived organoids
Published in Clinical and translational medicine (01-11-2022)“…Background Transketolase (TKT), a key rate‐limiting enzyme in the non‐oxidative branch of the pentose phosphate pathway (PPP), provides more than 85% of the…”
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9
Early Impairment of Synaptic and Intrinsic Excitability in Mice Expressing ALS/Dementia-Linked Mutant UBQLN2
Published in Frontiers in cellular neuroscience (20-09-2016)“…Frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) are believed to represent the different outcomes of a common pathogenic mechanism…”
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10
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis
Published in Archives of neurology (Chicago) (01-11-2011)“…The SQSTM1 gene encodes p62, a major pathologic protein involved in neurodegeneration. To examine whether SQSTM1 mutations contribute to familial and sporadic…”
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11
Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology
Published in Neurobiology of disease (01-03-2008)“…Abstract Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the selective loss of motor neurons (MNs). Approximately 10% of…”
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12
Molecular dissection of ALS-associated toxicity of SOD1 in transgenic mice using an exon-fusion approach
Published in Human molecular genetics (01-08-2008)“…Mutations in Cu,Zn superoxide dismutase (SOD1) are associated with amyotrophic lateral sclerosis (ALS). Among more than 100 ALS-associated SOD1 mutations,…”
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13
Elemental Fingerprint of Herbal Medicines Formed by Inductively Coupled Plasma Atomic Emission Spectroscopy (ICP - AES)
Published in Journal of engineering science and technology review (01-07-2013)“…Herbal medicines contain multiple compounds, each of which may be relevant to the medicine's pharmacological activity. A method referred to as 'elemental…”
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14
Distal axonopathy in an alsin-deficient mouse model
Published in Human molecular genetics (01-12-2007)“…Mutations in Alsin are associated with chronic juvenile amyotrophic lateral sclerosis (ALS2), juvenile primary lateral sclerosis and infantile-onset ascending…”
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15
p53-dependent radiation-induced crypt intestinal epithelial cells apoptosis is mediated in part through TNF-TNFR1 system
Published in Oncogene (15-02-2001)“…Radiation induces apoptosis of crypt intestinal epithelial cells (IEC) through a pathway that is largely dependent on p53. However, exactly how p53 mediates…”
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Potential of IStaphylea holocarpa/I Wood for Renewable Bioenergy
Published in Molecules (Basel, Switzerland) (01-12-2022)“…Energy is indispensable in human life and social development, but this has led to an overconsumption of non-renewable energy. Sustainable energy is needed to…”
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17
Deep learning for cross-domain data fusion in urban computing: Taxonomy, advances, and outlook
Published in Information fusion (01-01-2025)“…As cities continue to burgeon, Urban Computing emerges as a pivotal discipline for sustainable development by harnessing the power of cross-domain data fusion…”
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18
Immune index: A gene and cell prognostic signature for immunotherapy response prediction in hepatocellular carcinoma
Published in Pharmacological research (01-01-2023)“…The heterogeneity of tumor immune microenvironment (TIME) plays important roles in the development and immunotherapy response of hepatocellular carcinoma…”
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19
Carbon dioxide capture and green conversion to clean energy against global warming
Published in Advanced composites and hybrid materials (01-10-2024)“…Climate change and its impact on the environment and human health have become alarming concerns in recent years. The use of traditional energy sources such as…”
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20
Progress in advanced carbon nanotubes composites for air purification
Published in Advanced composites and hybrid materials (01-06-2024)“…Haze represents a significant environmental concern, arising from particulate matter accumulated in smoke, dust, and steam, and gaseous pollutants such as…”
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