Search Results - "Liu, Dinggang"
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1
Discovery of a new class of integrin antibodies for fibrosis
Published in Scientific reports (22-01-2021)“…Lung fibrosis, or the scarring of the lung, is a devastating disease with huge unmet medical need. There are limited treatment options and its prognosis is…”
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2
Renalase deficiency aggravates ischemic myocardial damage
Published in Kidney international (01-04-2011)“…Chronic kidney disease (CKD) leads to an 18-fold increase in cardiovascular complications not fully explained by traditional risk factors. Levels of renalase,…”
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3
Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1α–dependent function
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2012)“…Although intimately positioned between metabolic substrates in the bloodstream and the tissue parenchymal cells that require these substrates, a major role of…”
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4
Hypoxia-Inducible Factor-Dependent Degeneration, Failure, and Malignant Transformation of the Heart in the Absence of the von Hippel-Lindau Protein
Published in Molecular and Cellular Biology (01-06-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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5
Endothelial Expression of β1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling
Published in Molecular and Cellular Biology (01-01-2008)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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6
Problematic Internet use and the risk of suicide ideation in Chinese adolescents: A cross-sectional analysis
Published in Psychiatry research (01-08-2020)“…lPIU was significantly and independently associated with SI.lThe severity of PIU increased the risk of SI in adolescents.lPIU negatively interacted with…”
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7
Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis—Brief Report
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2016)“…OBJECTIVE—We hypothesized that the hypoxia-inducible factor (HIF) 1α in vascular smooth muscle contributes to the development of atherosclerosis, and links…”
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8
Cardiac myocyte‐specific HIF‐1α deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart
Published in The FASEB journal (01-07-2004)“…ABSTRACT At a resting pulse rate the heart consumes almost twice‐as much oxygen per gram tissue as the brain and more than 43 times more than resting skeletal…”
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9
Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1[alpha]-dependent function
Published in Proceedings of the National Academy of Sciences - PNAS (23-10-2012)“…Although intimately positioned between metabolic substrates in the bloodstream and the tissue parenchymal cells that require these substrates, a major role of…”
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10
Fine balance between HIF1 and HIF2 in smooth muscle is crucial for normal development and survival
Published in The FASEB journal (01-04-2011)“…Objective To investigate the role of the von Hippel‐Lindau (vHL) –hypoxia‐inducible factor (HIF)1 –HIF2 axis in vascular smooth muscle cells (SMC). Methods…”
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11
engineered VEGF-activating zinc finger protein transcription factor improves blood flow and limb salvage in advanced-age mice
Published in The FASEB journal (01-03-2006)“…Advances in understanding the relationship between protein structure and DNA binding specificity have made it possible to engineer zinc finger protein (ZFP)…”
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12
Endothelial Expression of Beta‐1 Integrin Is Required for Embryonic Vascular Patterning and Postnatal Vascular Remodeling
Published in The FASEB journal (01-03-2008)“…The largest subgroup of integrins is that containing the β1 subunit. Global deletion of β1 integrin expression results in embryonic lethality at ~E5, a…”
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13
936. Phage-Selected Motifs Internalize Via Multiple Endocytic Pathways and Facilitate Gene Delivery
Published in Molecular therapy (01-05-2004)“…The ability to direct internalization of macromolecules into cells or across endothelial barriers efficiently has tremendous therapeutic implications. Several…”
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14
Endothelial expression of beta1 integrin is required for embryonic vascular patterning and postnatal vascular remodeling
Published in Molecular and cellular biology (01-01-2008)“…The largest subgroup of integrins is that containing the beta1 subunit. beta1 integrins have been implicated in a wide array of biological processes ranging…”
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15
Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart
Published in The FASEB journal (01-07-2004)“…At a resting pulse rate the heart consumes almost twice-as much oxygen per gram tissue as the brain and more than 43 times more than resting skeletal muscle…”
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16
Histochemical study of transmyocardial laser channels in dogs
Published in Chinese medical journal (01-09-2001)“…Laser-induced myocardial injury was investigated in a canine transmyocardial laser revascularization model. A total of 23 channels were created in the left…”
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