Search Results - "Liu, Cunbao"

SARS‐CoV‐2 S1 is superior to the RBD as a COVID‐19 subunit vaccine antigen by Wang, Yunfei, Wang, Lichun, Cao, Han, Liu, Cunbao

“…Since its emergence in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has developed into a global pandemic within a matter of…”
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Tachyplesin Causes Membrane Instability That Kills Multidrug-Resistant Bacteria by Inhibiting the 3-Ketoacyl Carrier Protein Reductase FabG by Liu, Cunbao, Qi, Jialong, Shan, Bin, Ma, Yanbing

“…Tachyplesin is a type of cationic β-hairpin antimicrobial peptide discovered in horseshoe crab approximately 30 years ago that is well known for both its…”
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Employing Escherichia coli-derived outer membrane vesicles as an antigen delivery platform elicits protective immunity against Acinetobacter baumannii infection by Huang, Weiwei, Wang, Shijie, Yao, Yufeng, Xia, Ye, Yang, Xu, Li, Kui, Sun, Pengyan, Liu, Cunbao, Sun, Wenjia, Bai, Hongmei, Chu, Xiaojie, Li, Yang, Ma, Yanbing

“…Outer membrane vesicles (OMVs) have proven to be highly immunogenic and induced an immune response against bacterial infection in human clinics and animal…”
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ShSPI Inhibits Thrombosis Formation and Ischemic Stroke In Vivo by Luan, Ning, Cao, Han, Wang, Yunfei, Zhang, Haihao, Lin, Kangyang, Hu, Jingping, Rong, Mingqiang, Liu, Cunbao

“…Thrombotic diseases, emerging as a global public health hazard with high mortality and disability rates, pose a significant threat to human health and…”
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Immune Responses to Varicella-Zoster Virus Glycoprotein E Formulated with Poly(Lactic-co-Glycolic Acid) Nanoparticles and Nucleic Acid Adjuvants in Mice by Wang, Yunfei, Qi, Jialong, Cao, Han, Liu, Cunbao

“…The subunit herpes zoster vaccine Shingrix is superior to attenuated vaccine Zostavax in both safety and efficacy, yet its unlyophilizable liposome delivery…”
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Immunization against multidrug-resistant Acinetobacter baumannii effectively protects mice in both pneumonia and sepsis models by Huang, Weiwei, Yao, Yufeng, Long, Qiong, Yang, Xu, Sun, Wenjia, Liu, Cunbao, Jin, Xiaomei, Li, Yang, Chu, Xiaojie, Chen, Bin, Ma, Yanbing

“…Acinetobacter baumannii is considered the prototypical example of a multi- or pan- drug-resistant bacterium. It has been increasingly implicated as a major…”
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Comparison of Immune Responses between Inactivated and mRNA SARS-CoV-2 Vaccines Used for a Booster Dose in Mice by Luan, Ning, Cao, Han, Wang, Yunfei, Lin, Kangyang, Hu, Jingping, Liu, Cunbao

“…A large amount of real-world data suggests that the emergence of variants of concern (VOCs) has brought new challenges to the fight against SARS-CoV-2 because…”
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Encapsulation of Poly I:C and the natural phosphodiester CpG ODN enhanced the efficacy of a hyaluronic acid-modified cationic lipid-PLGA hybrid nanoparticle vaccine in TC-1-grafted tumors by Liu, Cunbao, Chu, Xiaojie, Yan, Mengmeng, Qi, Jialong, Liu, Hongxian, Gao, Fulan, Gao, Ruiyu, Ma, Guilei, Ma, Yanbing

“…[Display omitted] FDA approval of CpG oligodeoxynucleotide (CpG ODN) adjuvants for a human hepatitis B virus vaccine has been delayed until late 2017 because…”
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Immunogenicity of Varicella-Zoster Virus Glycoprotein E Formulated with Lipid Nanoparticles and Nucleic Immunostimulators in Mice by Cao, Han, Wang, Yunfei, Luan, Ning, Liu, Cunbao

“…Theoretically, the subunit herpes zoster vaccine Shingrix could be used as a varicella vaccine that avoids the risk of developing shingles from vaccination,…”
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Ionizable Lipid Nanoparticles Enhanced the Synergistic Adjuvant Effect of CpG ODNs and QS21 in a Varicella Zoster Virus Glycoprotein E Subunit Vaccine by Luan, Ning, Cao, Han, Wang, Yunfei, Lin, Kangyang, Liu, Cunbao

“…Varicella zoster virus (VZV) causes two diseases: varicella upon primary infection and herpes zoster when latent viruses in the sensory ganglia reactivate…”
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Th2-Oriented Immune Serum After SARS-CoV-2 Vaccination Does Not Enhance Infection In Vitro by Luan, Ning, Li, Tao, Wang, Yunfei, Cao, Han, Yin, Xingxiao, Lin, Kangyang, Liu, Cunbao

“…The relatively lower protection rate of the alum-adjuvanted inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines reminds us of the…”
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Systemic Responses of Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Following Exposure to the Antimicrobial Peptide Cathelicidin-BF Imply Multiple Intracellular Targets by Liu, Cunbao, Shan, Bin, Qi, Jialong, Ma, Yanbing

“…Cathelicidin-BF, derived from the banded krait ( ), is a typically cationic, amphiphilic and α-helical antimicrobial peptide (AMP) with 30 amino acids that…”
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Pretreatment with 3-methyladenine ameliorated Pseudomonas aeruginosa-induced acute pneumonia by inhibiting cell death of neutrophils in a mouse infection model by Yue, Lei, Cao, Han, Qi, Jialong, Yuan, Jin, Wang, Xin, Wang, Yunfei, Shan, Bin, Ke, Huaxin, Li, Hua, Luan, Ning, Liu, Cunbao

“…Pseudomonas aeruginosa is one of the leading causes of nosocomial infections worldwide. Clinical isolates that are resistant to multiple antimicrobials make it…”
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Effects of Varicella-Zoster Virus Glycoprotein E Carboxyl-Terminal Mutation on mRNA Vaccine Efficacy by Cao, Han, Wang, Yunfei, Luan, Ning, Lin, Kangyang, Liu, Cunbao

“…Glycoprotein E (gE) is one of the most abundant glycoproteins in varicella-zoster virus and plays pivotal roles in virus replication and transmission between…”
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Evaluation of the Immunological Efficacy of an LNP-mRNA Vaccine Prepared from Varicella Zoster Virus Glycoprotein gE with a Double-Mutated Carboxyl Terminus in Different Untranslated Regions in Mice by Wang, Yunfei, Cao, Han, Lin, Kangyang, Hu, Jingping, Luan, Ning, Liu, Cunbao

“…Cell-mediated immunity (CMI) plays a key role in the effectiveness of varicella zoster virus (VZV) vaccines, and mRNA vaccines have an innate advantage in…”
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Comparison of the Immune Effects of an mRNA Vaccine and a Subunit Vaccine against Herpes Zoster Administered by Different Injection Methods by Lin, Kangyang, Cao, Han, Luan, Ning, Wang, Yunfei, Hu, Jingping, Liu, Cunbao

“…Previous studies have shown that the herpes zoster subunit vaccine Shingrix™ performs well in clinical trials. However, the key ingredient in its adjuvant,…”
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An Established Th2-Oriented Response to an Alum-Adjuvanted SARS-CoV-2 Subunit Vaccine Is Not Reversible by Sequential Immunization with Nucleic Acid-Adjuvanted Th1-Oriented Subunit Vaccines by Cao, Han, Yang, Shengran, Wang, Yunfei, Luan, Ning, Yin, Xingxiao, Lin, Kangyang, Liu, Cunbao

“…A recently reported parallel preclinical study between a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine and an inactivated…”
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Effects of Rotavirus NSP4 on the Immune Response and Protection of Rotavirus-Norovirus Recombinant Subunit Vaccines in Different Immune Pathways by Hu, Jingping, Wu, Jinyuan, Cao, Han, Luan, Ning, Lin, Kangyang, Zhang, Haihao, Gao, Dandan, Lei, Zhentao, Li, Hongjun, Liu, Cunbao

“…Diarrheal disease continues to be a major cause of global morbidity and mortality among children under 5 years of age. To address the current issues associated…”
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Synergy effects of Polyinosinic-polycytidylic acid, CpG oligodeoxynucleotide, and cationic peptides to adjuvant HPV E7 epitope vaccine through preventive and therapeutic immunization in a TC-1 grafted mouse model by Liu, Cunbao, Chu, Xiaojie, Sun, Pengyan, Feng, Xuejun, Huang, Weiwei, Liu, Hongxian, Ma, Yanbing

“…Cross-talk by pattern recognition receptors may facilitate the maturation of dendritic cells and fine tune the immune response. Thus, the inclusion of ligands…”
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Antioxidant Peptidomics Reveals Novel Skin Antioxidant System by Yang, Hailong, Wang, Xu, Liu, Xiuhong, Wu, Jing, Liu, Cunbao, Gong, Weiming, Zhao, Zhiqiang, Hong, Jing, Lin, Donghai, Wang, Yizheng, Lai, Ren

“…It is generally agreed that reactive oxygen species (ROS) contribute to skin aging, skin disorders, and skin diseases. Skin possesses an extremely efficient…”
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