Search Results - "Liu, Congshan"
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Profiling of Transcriptome-Wide N6-Methyladenosine (m6A) Modifications and Identifying m6A Associated Regulation in Sperm Tail Formation in Anopheles sinensis
Published in International journal of molecular sciences (22-04-2022)“…Recent discoveries of reversible N6-methyladenosine (m6A) methylation on messenger RNA (mRNA) and mapping of m6A methylomes in many species have revealed…”
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Glycogen Phosphorylase: A Drug Target of Amino Alcohols in Echinococcus granulosus , Predicted by a Computer-Aided Method
Published in Frontiers in microbiology (23-11-2020)“…Echinococcosis is an important parasitic disease that threats human health and animal husbandry worldwide. However, the low cure rate of clinical drugs for…”
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3
Evolutionary History of RNA Modifications at N6-Adenosine Originating from the R-M System in Eukaryotes and Prokaryotes
Published in Biology (Basel, Switzerland) (28-01-2022)“…Methylation at the N6-position of adenosine (N6mA) on mRNA (m A) is one of the most widespread, highly selective and dynamically regulated RNA modifications…”
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4
Pharmacophore-Based Virtual Screening Toward the Discovery of Novel Anti-echinococcal Compounds
Published in Frontiers in cellular and infection microbiology (20-03-2020)“…Echinococcosis is a serious helminthic zoonosis with a great impact on human health and livestock husbandry. However, the clinically used drugs…”
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Silencing TUBB3 Expression Destroys the Tegument and Flame Cells of Echinococcus multilocularis Protoscoleces
Published in Animals (Basel) (19-09-2022)“…Alveolar echinococcosis (AE), caused by infection with the larvae of Echinococcus multilocularis, is a neglected tropical disease and zoonosis that causes…”
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Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model
Published in Parasites & vectors (24-01-2018)“…Cystic echinococcosis is a global public health problem; however, the drugs (albendazole and mebendazole) currently recommended by WHO for its treatment, have…”
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Improvement of Mitochondrial Activity and Fibrosis by Resveratrol Treatment in Mice with Schistosoma japonicum Infection
Published in Biomolecules (Basel, Switzerland) (25-10-2019)“…Schistosomiasis caused by is a major parasitic disease in the People's Republic of China. Liver fibrosis is the main pathological mechanism of schistosomiasis,…”
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Recombinant α- and β-tubulin from Echinococcus granulosus: expression, purification and polymerization
Published in Parasite (Paris) (2018)“…Echinococcosis, which causes a high disease burden and is of great public health significance, is caused by the larval stage of Echinococcus species. It has…”
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The proangiogenic role of polymorphonuclear myeloid-derived suppressor cells in mice infected with Echinococcus granulosus
Published in BioScience Trends (30-06-2018)“…The aim of this study was to first evaluate the proangiogenic activity of polymorphonuclear myeloid-derived suppressor cells (PMN-MDSC) in mice infected with…”
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Development and application of anthelminthic drugs in China
Published in Acta tropica (01-12-2019)“…China was once a country plagued by parasitic diseases. At the beginning of the founding of the People's Republic of China, nearly 80% of the population…”
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11
Geometrical incompatibility regulated pattern selection and morphological evolution in growing spherical soft tissues
Published in International journal of mechanical sciences (15-12-2024)“…Surface morphological patterns are widely observed in natural systems, which are closely correlated to vital biological functions and inspire surface…”
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Morphological instability of geometrically incompatible bilayer tubes
Published in International journal of mechanical sciences (01-05-2024)“…•The circumferential, 2D, and axial patterns observed in human intestine are reproduced in bilayer soft tubes by manipulating geometric…”
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13
Evaluation of PEN2-ATP6AP1 axis as an antiparasitic target for metformin based on phylogeny analysis and molecular docking
Published in Molecular and biochemical parasitology (01-09-2023)“…Metformin (Met), the first-line drug used in the treatment for type 2 diabetes mellitus, is effective against a variety of parasites. However, the molecular…”
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14
Harnessing Gravity‐Induced Instability of Soft Materials: Mechanics and Application
Published in Advanced functional materials (01-07-2024)“…This work offers a comprehensive overview of how gravity affects soft materials, with a particular emphasis on gravity‐induced instability. Soft materials,…”
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Extracellular vesicles secreted by Echinococcus multilocularis: important players in angiogenesis promotion
Published in Microbes and infection (01-09-2023)“…The involvement of Echinococcus multilocularis, and other parasitic helminths, in regulating host physiology is well recognized, but molecular mechanisms…”
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16
Wave propagation characteristics in a rotating soft cylinder
Published in International journal of solids and structures (01-03-2024)“…•Investigated the effects of the Coriolis and centrifugal forces on wave propagation.•Uncovered the discontinuous frequency change phenomena in rotating…”
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Growth and patterns of residually stressed core–shell soft sphere
Published in International journal of non-linear mechanics (01-12-2020)“…Many biological tissues and organisms are in a state of residual stress, which should be considered rather than ignored as in many previous studies. In this…”
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Prescribing patterns in growing tubular soft matter by initial residual stress
Published in Soft matter (30-10-2019)“…Initial residual stress is omnipresent in biological tissues and soft matter, and can affect growth-induced pattern selection significantly. Here we…”
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Geometrical incompatibility guides pattern selection in growing bilayer tubes
Published in Journal of the mechanics and physics of solids (01-12-2022)Get full text
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The RNA modification in Echinococcus granulosus cysts revealed by mass spectrometry
Published in Infection, genetics and evolution (01-12-2021)“…RNA modifications, as one of epigenetic mechanisms, are important and conserved mechanisms for maintaining the homeostasis of organisms. Little is known about…”
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