Search Results - "Liu, Cheri Z."
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Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity
Published in European journal of pharmacology (05-09-2021)“…Sigma-2 receptor/transmembrane protein 97 (TMEM97) is upregulated in cancer cells compared to normal cells. Traditional sigma-2 receptor agonists induce…”
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Abstract 1279: Sigma-2 receptor-mediated cell death is altered by cell density in human SK-N-SH neuroblastoma 2-D and 3-D cultures
Published in Cancer research (Chicago, Ill.) (15-07-2016)“…Abstract Sigma-2 receptors are highly expressed in tumor cell lines compared to normal cells and are more highly upregulated in proliferative than in quiescent…”
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Abstract 2017: The role of ceramide in the dual cytotoxic and metabolic stimulative effects of sigma-2 receptors
Published in Cancer research (Chicago, Ill.) (01-07-2017)“…Abstract Sigma-2 receptors are highly overexpressed in cancer cells compared to normal cells, as well as in proliferative versus quiescent cells. Sigma-2…”
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Abstract 2559: Pharmacological characterization of sigma-2 receptor ligand-induced metabolic stimulation in human SK-N-SH neuroblastoma cells
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract We have previously reported a novel metabolically stimulative function of the sigma-2 receptor, with stimulation of glycolytic hallmarks; effects…”
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Abstract 1671: Identification and characterization of MAM03055A, a novel bivalent sigma-2 receptor agonist
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Sigma-2 receptors are highly expressed in various types of cancer and mediate dual effects on cancer cell viability. Agonists induce programmed cell…”
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Abstract 1294: Differential sigma-2 receptor-mediated metabolic stimulative and apoptotic effects of monovalent CM571 and its homo-bivalent counterpart, MAM03055A
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Sigma-2 receptors, recently identified as TMEM97, are highly expressed in various types of cancer cells. Sigma-2 receptor agonists have traditionally…”
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