Search Results - "Liu, Cheri Z."

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  1. 1

    Identification and characterization of MAM03055A: A novel bivalent sigma-2 receptor/TMEM97 ligand with cytotoxic activity by Liu, Cheri Z., Mottinelli, Marco, Nicholson, Hilary E., McVeigh, Bridget M., Wong, Neelum K., McCurdy, Christopher R., Bowen, Wayne D.

    Published in European journal of pharmacology (05-09-2021)
    “…Sigma-2 receptor/transmembrane protein 97 (TMEM97) is upregulated in cancer cells compared to normal cells. Traditional sigma-2 receptor agonists induce…”
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    Journal Article
  2. 2

    Abstract 1279: Sigma-2 receptor-mediated cell death is altered by cell density in human SK-N-SH neuroblastoma 2-D and 3-D cultures by Liu, Cheri Z., Behnam, Vira, Bowen, Wayne D.

    Published in Cancer research (Chicago, Ill.) (15-07-2016)
    “…Abstract Sigma-2 receptors are highly expressed in tumor cell lines compared to normal cells and are more highly upregulated in proliferative than in quiescent…”
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    Journal Article
  3. 3

    Abstract 2017: The role of ceramide in the dual cytotoxic and metabolic stimulative effects of sigma-2 receptors by Liu, Cheri Z., Sukharevsky, Ellen, Bowen, Wayne D.

    Published in Cancer research (Chicago, Ill.) (01-07-2017)
    “…Abstract Sigma-2 receptors are highly overexpressed in cancer cells compared to normal cells, as well as in proliferative versus quiescent cells. Sigma-2…”
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  4. 4

    Abstract 2559: Pharmacological characterization of sigma-2 receptor ligand-induced metabolic stimulation in human SK-N-SH neuroblastoma cells by McVeigh, Bridget M., Oakes, Alissa K., Liu, Cheri Z., Mesangeau, Christophe, Alsharif, Walid F., McCurdy, Christopher R., Bowen, Wayne D.

    Published in Cancer research (Chicago, Ill.) (15-08-2020)
    “…Abstract We have previously reported a novel metabolically stimulative function of the sigma-2 receptor, with stimulation of glycolytic hallmarks; effects…”
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  5. 5

    Abstract 1671: Identification and characterization of MAM03055A, a novel bivalent sigma-2 receptor agonist by Liu, Cheri Z., Mottinelli, Marco, Nicholson, Hilary E., Zhong, Eric, McCurdy, Christopher R., Bowen, Wayne D.

    Published in Cancer research (Chicago, Ill.) (01-07-2018)
    “…Abstract Sigma-2 receptors are highly expressed in various types of cancer and mediate dual effects on cancer cell viability. Agonists induce programmed cell…”
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  6. 6

    Abstract 1294: Differential sigma-2 receptor-mediated metabolic stimulative and apoptotic effects of monovalent CM571 and its homo-bivalent counterpart, MAM03055A by Liu, Cheri Z., McVeigh, Bridget M., Mottinelli, Marco, Nicholson, Hilary E., McCurdy, Christopher R., Bowen, Wayne D.

    Published in Cancer research (Chicago, Ill.) (01-07-2019)
    “…Abstract Sigma-2 receptors, recently identified as TMEM97, are highly expressed in various types of cancer cells. Sigma-2 receptor agonists have traditionally…”
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    Journal Article