Search Results - "Liu, Bohao"
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PANI nanofibers-supported Nb2CTx nanosheets-enabled selective NH3 detection driven by TENG at room temperature
Published in Sensors and actuators. B, Chemical (15-01-2021)“…•A novel Nb2CTx/PANI-based NH3 sensor directly driven by a facile TENG is proposed.•The Nb2CTx/PANI-2 sensor exhibits a superior sensitivity (2.87 % ppm−1)…”
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Itaconate inhibits ferroptosis of macrophage via Nrf2 pathways against sepsis-induced acute lung injury
Published in Cell death discovery (02-02-2022)“…Itaconate, a metabolite produced during inflammatory macrophage activation, has been extensively described to be involved in immunoregulation, oxidative…”
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PM2.5-induced lung injury is attenuated in macrophage-specific NLRP3 deficient mice
Published in Ecotoxicology and environmental safety (15-09-2021)“…Fine particulate matter (PM2.5) is one of the most important components of environmental pollutants and is associated with lung injury. Pyroptosis, a form of…”
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Facilely constructed two-sided microstructure interfaces between electrodes and cellulose paper active layer: eco-friendly, low-cost and high-performance piezoresistive sensor
Published in Cellulose (London) (01-07-2021)“…The microstructure plays an important role in improving the sensing performance of pressure sensor. However, the design of microstructural active layer of…”
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Inflammatory Caspases Drive Pyroptosis in Acute Lung Injury
Published in Frontiers in pharmacology (05-02-2021)“…Acute lung injury (ALI), a critical respiratory disorder that causes diffuse alveolar injury leads to high mortality rates with no effective treatment. ALI is…”
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Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells
Published in Nature biomedical engineering (01-05-2018)“…The ability of extracellular vesicles (EVs) to regulate a broad range of cellular processes has recently been exploited for the treatment of diseases. For…”
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Cell type-specific microRNA therapies for myocardial infarction
Published in Science translational medicine (10-02-2021)“…Current interventions fail to recover injured myocardium after infarction and prompt the need for development of cardioprotective strategies. Of increasing…”
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DsbA-L mediated renal tubulointerstitial fibrosis in UUO mice
Published in Nature communications (18-09-2020)“…Recent studies have reported that upregulation of disulfide-bond A oxidoreductase-like protein (DsbA-L) prevented lipid-induced renal injury in diabetic…”
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HDAC3 deficiency protects against acute lung injury by maintaining epithelial barrier integrity through preserving mitochondrial quality control
Published in Redox biology (01-07-2023)“…Sepsis is one common cause of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), which is closely associated with high mortality in…”
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SIRT7 protects against liver fibrosis by suppressing stellate cell activation via TGF-β/SMAD2/3 pathway
Published in Biomedicine & pharmacotherapy (01-11-2024)“…SIRT7 is a class III HDACs deacetylase which plays critical roles in various biological processes. Aberrant SIRT7 expression is associated with tumorigenesis…”
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The Role of Histone Deacetylases in Acute Lung Injury-Friend or Foe
Published in International journal of molecular sciences (26-04-2023)“…Acute lung injury (ALI), caused by intrapulmonary or extrapulmonary factors such as pneumonia, shock, and sepsis, eventually disrupts the alveolar-capillary…”
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12
Opportunities and challenges in cardiac tissue engineering from an analysis of two decades of advances
Published in Nature biomedical engineering (01-04-2022)“…Engineered human cardiac tissues facilitate progress in regenerative medicine, disease modelling and drug development. In this Perspective, we reflect on the…”
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13
High performance ethylene sensor based on palladium-loaded tin oxide: Application in fruit quality detection
Published in Chinese chemical letters (01-08-2020)“…Ethylene (C2H4) is a crucial parameter to monitor due to its modulation of fruit ripening and its intrinsic significance to intelligent agriculture. In this…”
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14
Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy
Published in Cell death & disease (23-04-2022)“…Previous studies reported that RAGE participated in the process of kidney fibrosis, but the function and regulation pathway of RAGE in proximal tubular cells…”
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15
Pro-resolving lipid mediator ameliorates obesity induced osteoarthritis by regulating synovial macrophage polarisation
Published in Scientific reports (23-01-2019)“…Non-resolved persistent macrophage-mediated synovial inflammation is considered as one of the main drivers of both the establishment and progression of…”
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The role of HDAC3 and its inhibitors in regulation of oxidative stress and chronic diseases
Published in Cell death discovery (18-04-2023)“…HDAC3 is a specific and crucial member of the HDAC family. It is required for embryonic growth, development, and physiological function. The regulation of…”
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Comprehensive analysis of m6A modification in lipopolysaccharide-induced acute lung injury in mice
Published in Molecular medicine (Cambridge, Mass.) (22-01-2024)“…N6-Methyladenosine (m6A) methylation is the most prevalent post-transcriptional modification in mRNA, and plays significant roles in various diseases…”
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The role and therapeutic potential of itaconate in lung disease
Published in Cellular & molecular biology letters (01-10-2024)“…Lung diseases triggered by endogenous or exogenous factors have become a major concern, with high morbidity and mortality rates, especially after the…”
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Sorafenib/2800Z Co-Loaded into Cholesterol and PEG Grafted Polylysine NPs for Liver Cancer Treatment
Published in Pharmaceuticals (Basel, Switzerland) (13-01-2023)“…The treatment of liver cancer remains challenging due to the low responsiveness of advanced cancer to therapeutic options. Sorafenib is the first line…”
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Discovery of SIRT7 Inhibitor as New Therapeutic Options Against Liver Cancer
Published in Frontiers in cell and developmental biology (31-01-2022)“…Optimal therapeutic strategies for liver cancer patients remain challenging due to the high recurrence rate after surgical resection and chemotherapy…”
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