Search Results - "Liu, Alan King Lun"

Nucleus basalis of Meynert revisited: anatomy, history and differential involvement in Alzheimer’s and Parkinson’s disease by Liu, Alan King Lun, Chang, Raymond Chuen-Chung, Pearce, Ronald K. B., Gentleman, Steve M.

“…It has been well established that neuronal loss within the cholinergic nucleus basalis of Meynert (nbM) correlates with cognitive decline in dementing…”
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Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues by Lai, Hei Ming, Liu, Alan King Lun, Ng, Harry Ho Man, Goldfinger, Marc H., Chau, Tsz Wing, DeFelice, John, Tilley, Bension S., Wong, Wai Man, Wu, Wutian, Gentleman, Steve M.

“…Modern clearing techniques for the three-dimensional (3D) visualisation of neural tissue microstructure have been very effective when used on rodent brain but…”
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Prominent astrocytic alpha-synuclein pathology with unique post-translational modification signatures unveiled across Lewy body disorders by Altay, Melek Firat, Liu, Alan King Lun, Holton, Janice L, Parkkinen, Laura, Lashuel, Hilal A

“…Alpha-synuclein (aSyn) is a pre-synaptic monomeric protein that can form aggregates in neurons in Parkinson's disease (PD), Parkinson's disease with dementia…”
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Hippocampal CA2 Lewy pathology is associated with cholinergic degeneration in Parkinson's disease with cognitive decline by Liu, Alan King Lun, Chau, Tsz Wing, Lim, Ernest Junwei, Ahmed, Idil, Chang, Raymond Chuen-Chung, Kalaitzakis, Michail E, Graeber, Manuel B, Gentleman, Steve M, Pearce, Ronald K B

“…Although the precise neuropathological substrates of cognitive decline in Parkinson's disease (PD) remain elusive, it has long been regarded that pathology in…”
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Rationalisation and Validation of an Acrylamide-Free Procedure in Three-Dimensional Histological Imaging by Lai, Hei Ming, Liu, Alan King Lun, Ng, Wai-Lung, DeFelice, John, Lee, Wing Sang, Li, Heng, Li, Wen, Ng, Ho Man, Chang, Raymond Chuen-Chung, Lin, Bin, Wu, Wutian, Gentleman, Steve M

“…Three-dimensional visualization of intact tissues is now being achieved by turning tissues transparent. CLARITY is a unique tissue clearing technique, which…”
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Author Correction: Next generation histology methods for three-dimensional imaging of fresh and archival human brain tissues by Lai, Hei Ming, Liu, Alan King Lun, Ng, Harry Ho Man, Goldfinger, Marc H., Chau, Tsz Wing, DeFelice, John, Tilley, Bension S., Wong, Wai Man, Wu, Wutian, Gentleman, Steve M.

“…In the original version of this Article, the concentration of boric acid buffer for the SDS clearing solution was given incorrectly as ‘1 M sodium borate’ and…”
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ARTAG in the basal forebrain: widening the constellation of astrocytic tau pathology by Liu, Alan King Lun, Goldfinger, Marc H, Questari, Hayleigh E, Pearce, Ronald K B, Gentleman, Steve M

“…Keywords: Chronic traumatic encephalopathy, Aging-related tau astrogliopathy, Basal forebrain, Tauopathy…”
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Differential expression of galanin in the cholinergic basal forebrain of patients with Lewy body disorders by Alexandris, Athanasios, Liu, Alan King Lun, Chang, Raymond Chuen-Chung, Pearce, Ronald K B, Gentleman, Steve M

“…Depletion of cholinergic neurons within the nucleus basalis of Meynert (nbM) is thought to contribute to the development of cognitive impairments in both…”
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Neuropathological Assessment as an Endpoint in Clinical Trial Design by Gentleman, Steve, Liu, Alan King Lun

“…Different neurodegenerative conditions can have complex, overlapping clinical presentations that make accurate diagnosis during life very challenging. For this…”
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Possible Contribution of Altered Cholinergic Activity in the Visual Cortex in Visual Hallucinations in Parkinson’s Disease by Sinclair, Lindsey, Brenton, Jake, Liu, Alan King Lun, MacLachlan, Rob, Gentleman, Steve M, Love, Seth

“…Objective:Up to one-third of patients with Parkinson’s disease (PD) experience visual hallucinations (VHs). Lewy bodies are sparse in the visual cortices and…”
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Neuropathological Assessment as an Endpoint in Clinical Trial Design by Gentleman, Steve M, Liu, Alan King Lun

“…Different neurodegenerative conditions can have complex, overlapping clinical presentations that make accurate diagnosis during life very challenging. For this…”
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12.30 Do anticholinergic drugs increase alzheimer’s pathology in parkinson’s patients? A retrospective post-mortem investigation by Lim, Yau Mun, Pearce, Ronald KB, Gentleman, Steve M

“…IntroductionRecent studies have highlighted the accumulated use of anticholinergic drugs is associated with an increased risk of dementia, and many of those…”
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Acute urinary retention in a 27-year-old male secondary to benign prostatic hyperplasia treated with Holmium Enucleation of the Prostate (HOLEP) by Napier-Hemy, Timothy P, Liu, Alan King Lun, Floyd, Michael S, McNulty, Sid, Omar, Ahmad M, Mistry, Rahul, Gana, Hosea BY

“…Introduction: Benign prostatic hyperplasia (BPH) is common in the ageing male. Clinical manifestations like retention impact on a patient’s quality of life…”
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Stem cell therapy for Alzheimer's disease: hype or hope? by Liu, A. K. L.

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Clinicopathological investigations of the cholinergic basal forebrain in lewy body disorders and ageing by Liu, Alan King Lun

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