Search Results - "Litzky, L A"

Evaluation of EGFR mutation status in cytology specimens: An institutional experience by Aisner, D. L., Deshpande, C., Baloch, Z., Watt, C. D., Litzky, L. A., Malhotra, B., Sepulveda, A. R., Langer, C., Evans, T., Van Deerlin, V. M.

“…Epidermal growth factor receptor (EGFR) mutation status has been shown to predict response to anti‐EGFR tyrosine kinase inhibitors in non‐small cell lung…”
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Predicted Rate of Secondary Malignancies Following Adjuvant Proton Versus Photon Radiation Therapy for Thymoma by Vogel, J, Lin, L, Litzky, L.A, Berman, A.T, Simone, C.B

“…Purpose Thymic malignanices are the most common tumors of the anterior mediastinum. The benefit of adjuvant radiation for stage II disease remains…”
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Telomerase expression in respiratory epithelium during the multistage pathogenesis of lung carcinomas by YASHIMA, K, LITZKY, L. A, GAZDAR, A. F, KAISER, L, ROGERS, T, LAM, S, WISTUBA, I. I, MILCHGRUB, S, SRIVASTAVA, S, PIATYSZEK, M. A, SHAY, J. W

“…To investigate the role of telomerase in the multistage pathogenesis of lung cancer, we examined 205 fresh and archival tissue samples obtained from 40…”
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Wilms' tumor 1 susceptibility (WT1) gene products are selectively expressed in malignant mesothelioma by Amin, KM, Litzky, LA, Smythe, WR, Mooney, AM, Morris, JM, Mews, DJ, Pass, HI, Kari, C, Rodeck, U, Rauscher, FJ, 3rd

“…The distinction between malignant mesothelioma and other neoplastic processes involving the pleura is difficult, partly due to the lack of specific markers…”
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Gene therapy using adenovirus carrying the herpes simplex-thymidine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer by Hwang, H C, Smythe, W R, Elshami, A A, Kucharczuk, J C, Amin, K M, Williams, J P, Litzky, L A, Kaiser, L R, Albelda, S M

“…Previous studies have shown adenoviral transfer of the herpes simplex virus thymidine kinase (HSVtk) gene followed by the anti-viral drug ganciclovir (GCV) can…”
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Analysis of Epstein-Barr virus-associated posttransplantation lymphoproliferative disorder after lung transplantation by Montone, Kathleen T., Litzky, Leslie A., Wurster, Angela, Kaiser, Larry, Bavaria, Joseph, Kotloff, Robert, Palevsky, Harold, Pietra, Giuseppe G., Tomaszewski, John E.

“…Background. Epstein-Barr virus (EBV)-associated posttransplantation lymphoproliferative disorder (PTLD) is a serious complication of lung transplantation…”
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Successful Liver, Kidney, and Pancreas Transplantation From a Donor With Cerebral Emboli From a Left Atrial Myxoma by Canter, R.J., Abt, P.L., Litzky, L.A., Frank, A., Abt, A.B., Sellers, M.T., Markmann, J.F., Olthoff, K.M., Naji, A., Shaked, A.

“…Although transmission and engraftment of donor-derived malignancies is rare in recipients of solid organ transplants, it is associated with unfavorable…”
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Rapid method for detection of Aspergillus 5S ribosomal RNA using a genus-specific oligonucleotide probe by Montone, K T, Litzky, L A

“…Ribosomal RNA (rRNA) is present in all prokaryotic and eukaryotic cells. Although sequences are conserved, variations in nucleic acid composition are known to…”
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Use of a replication-restricted herpes virus to treat experimental human malignant mesothelioma by KUCHARCZUK, J. C, RANDAZZO, B, LITZKY, L. A, FRASER, N. W, ALBELDA, S. M, KAISER, L. R, CHANG, M. Y, AMIN, K. M, ELSHAMI, A. A, STERMAN, D. H, RIZK, N. P, MOLNAR-KIMBER, K. L, BROWN, S. M, MACLEAN, A. R

“…Modified, nonneurovirulent herpes simplex viruses (HSVs) have shown promise in the treatment of brain tumors. However, HSV-1 can infect and lyse a wide range…”
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Adenovirus-mediated herpes simplex virus thymidine kinase/ganciclovir gene therapy in patients with localized malignancy: results of a phase I clinical trial in malignant mesothelioma by Sterman, D H, Treat, J, Litzky, L A, Amin, K M, Coonrod, L, Molnar-Kimber, K, Recio, A, Knox, L, Wilson, J M, Albelda, S M, Kaiser, L R

“…Malignant pleural mesothelioma is a fatal neoplasm that is unresponsive to standard modalities of cancer therapy. We conducted a phase I dose-escalation…”
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The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene by ELSHAMI, A. A, KUCHARCZUK, J. C, STERMAN, D. H, SMYTHE, W. R, HWANG, H. C, AMIN, K. M, LITZKY, L. A, ALBELDA, S. M, KAISER, L. R

“…To determine whether the immune system limits or improves the therapeutic efficacy of an adenovirus vector expressing the herpes simplex thymidine kinase…”
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Cytokeratin immunoreactivity in malignant fibrous histiocytoma and spindle cell tumors: comparison between frozen and paraffin-embedded tissues by Litzky, L A, Brooks, J J

“…Cytokeratin (CK) immunoreactivity in malignant fibrous histiocytoma (MFH) and other selected cases of spindle cell tumors were assessed using two cytokeratin…”
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Comparison of Molecular Changes in Lung Cancers in HIV-Positive and HIV-Indeterminate Subjects by Wistuba, Ignacio I, Behrens, Carmen, Milchgrub, Sara, Virmani, Arvind K, Jagirdar, Jaishree, Thomas, Bilue, Ioachim, Harry L, Litzky, Leslie A, Brambilla, Elisabeth M, Minna, John D, Gazdar, Adi F

“…CONTEXT.— Human immunodeficiency virus (HIV) infection has been associated with an increasing incidence of malignancy, and HIV-infected persons have an…”
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The pathology of fungal disease in the lung by Litzky, Leslie A.

“…The gross and histological appearance of pulmonary mycotic disease is rarely pathognomonic for a particular entity. Tissue obtained through an invasive…”
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Transfer of the CFTR gene to the lung of nonhuman primates with E1-deleted, E2a-defective recombinant adenoviruses: a preclinical toxicology study by Goldman, M J, Litzky, L A, Engelhardt, J F, Wilson, J M

“…This paper describes a preclinical toxicology study designed to investigate the biological efficacy and safety profile of second-generation adenovirus for CFTR…”
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Bilateral sequential lung transplantation for pulmonary alveolar microlithiasis by Edelman, J D, Bavaria, J, Kaiser, L R, Litzky, L A, Palevsky, H I, Kotloff, R M

“…Pulmonary alveolar microlithiasis (PAM) is characterized by deposition of calcium phosphate within the alveolar airspaces. There is currently no effective…”
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Treatment of pleural mesothelioma in an immunocompetent rat model utilizing adenoviral transfer of the herpes simplex virus thymidine kinase gene by Elshami, A A, Kucharczuk, J C, Zhang, H B, Smythe, W R, Hwang, H C, Litzky, L A, Kaiser, L R, Albelda, S M

“…Previously, we have treated malignant mesothelioma (MM) growing in the peritoneal cavity of immunodeficient mice utilizing a recombinant adenovirus vector…”
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Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates by Kucharczuk, J C, Raper, S, Elshami, A A, Amin, K M, Sterman, D H, Wheeldon, E B, Wilson, J M, Litzky, L A, Kaiser, L R, Albelda, S M

“…Preclinical safety and toxicity studies of intrapleural administration of recombinant adenovirus carrying the herpes simplex thymidine kinase gene…”
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Herpes simplex 1716--an ICP 34.5 mutant--is severely replication restricted in human skin xenografts in vivo by Randazzo, B P, Kucharczuk, J C, Litzky, L A, Kaiser, L R, Brown, S M, MacLean, A, Albelda, S M, Fraser, N W

“…HSV-1716 is a replication-restricted, neuroattenuated ICP 34.5 gene mutant of herpes simplex virus type 1 (HSV-1). Because of the attenuated phenotype of ICP…”
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Pleural-based mesothelioma in immune competent rats: A model to study adenoviral gene transfer by Kucharczuk, John C., Elshami, Ashraf A., Zhang, Hong Bing, Smythe, W. Roy, Hwang, Harry C., Tomlinson, James S., Amin, Kunjlata M., Litzky, Leslie A., Albelda, Steven M., Kaiser, Larry R.

“…Despite multimodality approaches, pleural-based malignant mesothelioma remains a disease with a very poor prognosis. Novel therapeutic strategies such as gene…”
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