Search Results - "Litzenberg, Kevin T."
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NNMT Silencing Activates Tumor Suppressor PP2A, Inactivates Oncogenic STKs, and Inhibits Tumor Forming Ability
Published in Clinical cancer research (01-05-2017)“…To identify potential molecular hubs that regulate oncogenic kinases and target them to improve treatment outcomes for glioblastoma patients. Data mining of…”
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Methionine and Kynurenine Activate Oncogenic Kinases in Glioblastoma, and Methionine Deprivation Compromises Proliferation
Published in Clinical cancer research (15-07-2016)“…We employed a metabolomics-based approach with the goal to better understand the molecular signatures of glioblastoma cells and tissues, with an aim toward…”
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Cancer Is an Independent Risk Factor for Acute Respiratory Distress Syndrome in Critically Ill Patients: A Single Center Retrospective Cohort Study
Published in Journal of intensive care medicine (01-03-2022)“…Background: Acute Respiratory Distress Syndrome (ARDS) is a frequent cause of respiratory failure in intensive care unit (ICU) patients and results in…”
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Lack of Constitutively Active DNA Repair Sensitizes Glioblastomas to Akt Inhibition and Induces Synthetic Lethality with Radiation Treatment in a p53-Dependent Manner
Published in Molecular cancer therapeutics (01-02-2018)“…Treatment refractory glioblastoma (GBM) remains a major clinical problem globally, and targeted therapies in GBM have not been promising to date. The Cancer…”
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Cells isolated from residual intracranial tumors after treatment express iPSC genes and possess neural lineage differentiation plasticity
Published in EBioMedicine (01-10-2018)“…The goal of this study is to identify and characterize treatment resistant tumor initiating cells (TRTICs) using orthotopic xenografts. TRTICs were enriched…”
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Cells isolated from residual intracranial tumors after treatment express iPSC genes and possess neural lineage differentiation plasticityResearch in context
Published in EBioMedicine (01-10-2018)“…Background: The goal of this study is to identify and characterize treatment resistant tumor initiating cells (TRTICs) using orthotopic xenografts. Methods:…”
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