Search Results - "Litwa, E."
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Bazedoxifene and raloxifene protect neocortical neurons undergoing hypoxia via targeting ERα and PPAR-γ
Published in Molecular and cellular endocrinology (05-02-2018)“…Selective estrogen receptor modulators (SERMs) such as bazedoxifene and raloxifene are recognized to mainly act via estrogen receptors (ERs), but there is no…”
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RXRα, PXR and CAR xenobiotic receptors mediate the apoptotic and neurotoxic actions of nonylphenol in mouse hippocampal cells
Published in The Journal of steroid biochemistry and molecular biology (01-02-2016)“…•Nonylphenol (NP) induced apoptosis and toxicity in mouse hippocampal cells.•NP stimulated xenobiotic receptors RXRα, PXR and CAR-specific…”
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The key involvement of estrogen receptor β and G-protein-coupled receptor 30 in the neuroprotective action of daidzein
Published in Neuroscience (15-05-2013)“…Highlights ► This study has demonstrated a key role of ERβ and GPR30 in the neuroprotective action of daidzein. ► Daidzein inhibited glutamate-induced…”
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Selective Aryl Hydrocarbon Receptor Modulator 3,3′-Diindolylmethane Impairs AhR and ARNT Signaling and Protects Mouse Neuronal Cells Against Hypoxia
Published in Molecular neurobiology (01-10-2016)“…The neuroprotective potential of 3,3′-diindolylmethane (DIM), which is a selective aryl hydrocarbon receptor modulator, has recently been shown in cellular and…”
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Exposure to chronic stress impairs the ability to cope with an acute challenge: Modulation by lurasidone treatment
Published in European neuropsychopharmacology (01-08-2022)“…Chronic stress represents a major contributor for the development of mental illness. This study aimed to investigate how animals exposed to chronic mild stress…”
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Apoptotic and neurotoxic actions of 4-para-nonylphenol are accompanied by activation of retinoid X receptor and impairment of classical estrogen receptor signaling
Published in The Journal of steroid biochemistry and molecular biology (01-10-2014)“…•Age-dependent action of nonylphenol (NP) on mouse neuronal cells was demonstrated.•Estrogen receptor (ER) antagonists potentiated the NP-induced apoptosis and…”
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Neuroprotective action of raloxifene against hypoxia-induced damage in mouse hippocampal cells depends on ERα but not ERβ or GPR30 signalling
Published in The Journal of steroid biochemistry and molecular biology (01-02-2015)“…•Neuroprotective action of raloxifene against hypoxia-induced damage was demonstrated.•Hypoxia decreased Erα mRNA but increased Erβ and Gpr30 mRNA…”
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The Crucial Involvement of Retinoid X Receptors in DDE Neurotoxicity
Published in Neurotoxicity research (01-01-2016)“…Dichlorodiphenyldichloroethylene (DDE) is a primary environmental and metabolic degradation product of the pesticide dichlorodiphenyltrichloroethane (DDT). It…”
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Isomer-nonspecific action of dichlorodiphenyltrichloroethane on aryl hydrocarbon receptor and G-protein-coupled receptor 30 intracellular signaling in apoptotic neuronal cells
Published in Molecular and cellular endocrinology (05-07-2014)“…•DDT-induced apoptosis of neuronal cells depends on caspase-9, caspase-3, and GSK3β.•DDT-induced apoptosis involves p,p’-DDT-specific impairment of classical…”
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The effect of antidepressant treatment on the activity of liver cytochrome P450 (CYP) during chronic mild stress (CMS)
Published in European neuropsychopharmacology (01-10-2016)Get full text
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P.2.21 Effects of “pulse therapy” with imipramine in the chronic mild stress model in rats
Published in European neuropsychopharmacology (2007)Get full text
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EFFECTS OF SELECTIVE LESION OF THE VENTRAL HIPPOCAMPUS AND CHRONIC VENLAFAXINE ADMINISTRATION ON THE BEHAVIOR OF ANIMALS EXPOSED TO THE CHRONIC MILD STRESS MODEL OF DEPRESSION
Published in Acta neurobiologiae experimentalis (01-01-2022)“…Injections of ibotenic acid (IBO) to the ventral hippocampus (vHPC) results in a specific damage that changes in the activity of cortical and limbic…”
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S.16.01 Mutual activation of muscarinic and mGlu2 receptors as a new treatment of schizophrenia-related cognitive deficits
Published in European neuropsychopharmacology (01-12-2019)Get full text
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