A physical model of blood platelets shape and its effect on light scattering

Quantitative description of blood platelet shape and its dramatic change during activation is necessary for the correct interpretation of light-scattering data, routinely measured in diagnostic laboratories. We propose the model of platelet shape, based on the known information on the cell cytoskele...

Full description

Saved in:

Bibliographic Details
Published in:	2016 URSI International Symposium on Electromagnetic Theory (EMTS) pp. 583 - 585
Main Authors:	Moskalensky, Alexander E., Litvinenko, Alyona L., Nekrasov, Vyacheslav M., Yurkin, Maxim A.
Format:	Conference Proceeding
Language:	English
Published:	IEEE 01-08-2016
Subjects:	Blood platelets Geometry Light scattering Shape Shape measurement Solid modeling
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

Description
Summary:	Quantitative description of blood platelet shape and its dramatic change during activation is necessary for the correct interpretation of light-scattering data, routinely measured in diagnostic laboratories. We propose the model of platelet shape, based on the known information on the cell cytoskeleton. The model geometry is characterized by two parameters: the cell volume and the overcurvature of the internal microtubule bundle, which changes during platelet activation. We describe the procedure for the construction of a cell shape given the volume and overcurvature, and also the way for simulation of light scattering by such objects.
DOI:	10.1109/URSI-EMTS.2016.7571460