Search Results - "Litvak, David A"

Laparoscopic Splenectomy in Colorectal Cancer Patients with Chemotherapy-Associated Thrombocytopenia due to Hypersplenism by Litvak, David A., Malad, Salman, Wascher, Robert A., Markman, Maurie, Niu, Jiaxin

“…Background: Hypersplenism due to chemotherapy-related liver injury has been associated with severe thrombocytopenia that may preclude continuation of systemic…”
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Targeting Ceramide Metabolism—a Strategy for Overcoming Drug Resistance by Senchenkov, Alex, Litvak, David A., Cabot, Myles C.

“…Inherent or acquired drug resistance, which frequently characterizes cancer cells, is caused by multiple mechanisms, including dysfunctional metabolism of the…”
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Endogenous immune response to early- and intermediate-stage melanoma is correlated with outcomes and is independent of locoregional relapse and standard prognostic factors by Litvak, David A, Gupta, Rishab K, Yee, Reynold, Wanek, Leslie A, Ye, Wei, Morton, Donald L

“…Standard prognostic factors, including precise staging of the regional lymph nodes, cannot accurately determine which early-stage melanomas will metastasize…”
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Modulators of Ceramide Metabolism Sensitize Colorectal Cancer Cells to Chemotherapy: A Novel Treatment Strategy by Litvak, David A, Bilchik, Anton J, Cabot, Myles C

“…Irinotecan is a first-line chemotherapeutic agent for patients with metastatic colorectal cancer (CRC). Response rates of less than 40% underscore the problem…”
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Treatment of elderly breast cancer patients in a community hospital setting by Litvak, David A, Arora, Rajeev

“…Elderly breast cancer patients are underdiagnosed and undertreated in a community hospital setting. Retrospective study of tumor registry patients. Community…”
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The results of the Department of Defense's breast lymphatic mapping study by Litvak, David A, Giuliano, Armando E

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Signaling mechanisms regulating bombesin-mediated AP-1 gene induction in the human gastric cancer SIIA by Kim, H J, Evers, B M, Litvak, D A, Hellmich, M R, Townsend, Jr, C M

“…The hormone bombesin (BBS) and its mammalian equivalent gastrin-releasing peptide (GRP) act through specific GRP receptors (GRP-R) to affect multiple cellular…”
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Surgery in the aged population: surgical oncology by Monson, Keith, Litvak, David A, Bold, Richard J

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Glucagon-like peptide 2 is a potent growth factor for small intestine and colon by Litvak, David A., Hellmich, Mark R., Evers, B.Mark, Banker, Nitesh A., Townsend, Courtney M.

“…Factors that stimulate gut mucosal proliferation may be beneficial during periods of gut disuse or atrophy. Recently glucagon-like peptide 2 (GLP-2) has been…”
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Systemic irinotecan and regional floxuridine after hepatic cytoreduction in 185 patients with unresectable colorectal cancer metastases by Litvak, David A, Wood, Thomas F, Tsioulias, George J, Chung, Mathew, Chawla, Sant P, Foshag, Leland J, Morton, Donald L, Ramming, Kenneth P, Bilchik, Anton J

“…This study evaluated our 7-year experience treating unresectable colorectal cancer (CRC) hepatic metastases refractory to systemic 5-fluorouracil. A total of…”
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Enterotrophic effects of glucagon-like peptide 2 are enhanced by neurotensin by Litvak, David A., Evers, B.Mark, Hellmich, Mark R., Townsend, Courtney M.

“…Combination therapy with enterotrophic agents may be useful in patients with the short bowel syndrome. The gut hormones neurotensin (NT) and glucagon-like…”
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Targeting molecular pathways with camptothecin as novel therapy for gastric cancer by Litvak, David A., Papaconstantinou, Harry T., Evers, B.Mark, Townsend, Courtney M.

“…Novel chemotherapeutic agents are needed to treat gastric cancer for which the prognosis remains dismal. The antitumor alkaloid camptothecin (CPT) may be…”
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Characterization of two novel proabsorptive peptide YY analogs, BIM-43073D and BIM-43004C by LITVAK, D. A, ISEKI, H, EVERS, B. M, GREELEY, G. H, HELLMICH, M. R, IWASE, K, BALASUBRAMANIAM, A, TOWNSEND, C. M

“…Effective clinical therapy to augment intestinal absorption of water and electrolytes does not exist; the gut hormone, peptide YY (PYY), is a potent…”
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Cytoreductive surgery (CRC) and heated intraperitoneal chemotherapy (HIPEC) in patients with platinum resistant epithelial ovarian cancer (PROC) by El Halabi, Hatem M., Williams, Sybilann, Huss, Harold Theodore, Bieligk, Samuel C., Flynn, Rod, Del Priore, Giuseppe, Gupta, Digant, Taha, Mahdi, Litvak, David A., Markman, Maurie, Gilmore, Laura, Brown, Charles K.

“…Abstract only…”
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The Results of the Department of Defense's Breast Lymphatic Mapping Study by Litvak, D. A.

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Modulators of Ceramide Metabolism Sensitize Colorectal Cancer Cells to Chemotherapy by Litvak, David A, Bilchik, Anton J, Cabot, Myles C

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Targeting Ceramide Metabolism--a Strategy for Overcoming Drug Resistance: p. 388 by Senchenkov, Alex, Litvak, David A, Cabot, Myles C

“…Inherent or acquired drug resistance, which frequently characterizes cancer cells, is caused by multiple mechanisms, including dysfunctional metabolism of the…”
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Induction of apoptosis in human gastric cancer by sodium butyrate by Litvak, D A, Hwang, K O, Evers, B M, Townsend, Jr, C M

“…Novel therapeutic agents are needed in the adjuvant treatment of gastric cancer. The differentiating agent sodium butyrate (NaBT) inhibits the growth of colon…”
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Intestinal adaptation and enterocyte apoptosis following small bowel resection is p53 independent by Shin, C E, Falcone, Jr, R A, Kemp, C J, Erwin, C R, Litvak, D A, Evers, B M, Warner, B W

“…Adaptation following small bowel resection (SBR) signals enterocyte proliferation and apoptosis. Because p53-induced p21(waf1/cip1) may be important for…”
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Inhibition of gastric cancer by camptothecin involves apoptosis and multiple cellular pathways by Litvak, David A., Papaconstantinou, Harry T., Hwang, Kevin O., Kim, Mimi, Evers, B.Mark, Townsend, Courtney M.

“…Background: The prognosis for gastric cancer remains dismal; novel agents that target specific molecular pathways are needed as adjuvant therapy. Camptothecin…”
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