Search Results - "Litty, Dennis"
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Butyrate production in the acetogen Eubacterium limosum is dependent on the carbon and energy source
Published in Microbial biotechnology (01-11-2021)“…Summary Eubacterium limosum KIST612 is one of the few acetogenic bacteria that has the genes encoding for butyrate synthesis from acetyl‐CoA, and indeed, E…”
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Structural Elements Involved in ATP Hydrolysis Inhibition and ATP Synthesis of Tuberculosis and Nontuberculous Mycobacterial F-ATP Synthase Decipher New Targets for Inhibitors
Published in Antimicrobial agents and chemotherapy (20-12-2022)“…The F F -ATP synthase is required for the viability of tuberculosis (TB) and nontuberculous mycobacteria (NTM) and has been validated as a drug target. Here,…”
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Targeting Mycobacterial F-ATP Synthase C-Terminal α Subunit Interaction Motif on Rotary Subunit γ
Published in Antibiotics (Basel) (26-11-2021)“…Mycobacteria regulate their energy (ATP) levels to sustain their survival even in stringent living conditions. Recent studies have shown that mycobacteria not…”
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GaMF1.39's antibiotic efficacy and its enhanced antitubercular activity in combination with clofazimine, Telacebec, ND-011992, or TBAJ-876
Published in Microbiology spectrum (12-12-2023)“…New drugs are needed to combat multidrug-resistant tuberculosis. The electron transport chain (ETC) maintains the electrochemical potential across the…”
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Enantiomer discrimination in β-phenylalanine degradation by a newly isolated Paraburkholderia strain BS115 and type strain PsJN
Published in AMB Express (21-09-2018)“…Despite their key role in numerous natural compounds, β-amino acids have rarely been studied as substrates for microbial degradation. Fermentation of the newly…”
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A Na + A 1 A O ATP synthase with a V-type c subunit in a mesophilic bacterium
Published in The FEBS journal (01-07-2020)“…A A ATP synthases with a V-type c subunit have only been found in hyperthermophilic archaea which makes bioenergetic analyses impossible due to the instability…”
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A Na+ A1AO ATP synthase with a V‐type c subunit in a mesophilic bacterium
Published in The FEBS journal (01-07-2020)“…A1AO ATP synthases with a V‐type c subunit have only been found in hyperthermophilic archaea which makes bioenergetic analyses impossible due to the…”
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One substrate, many fates: different ways of methanol utilization in the acetogen Acetobacterium woodii
Published in Environmental microbiology (01-07-2022)“…Summary Acetogenic bacteria such as Acetobacterium woodii use the Wood–Ljungdahl pathway (WLP) for fixation of CO2 and energy conservation. This pathway…”
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ATP synthesis in an ancient ATP synthase at low driving forces
Published in Proceedings of the National Academy of Sciences - PNAS (10-05-2022)“…Hyperthermophilic archaea are close to the origin of life. Some hyperthermophilic anaerobic archaea live under strong energy limitation and have to make a…”
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Biosynthesis of butyrate from methanol and carbon monoxide by recombinant Acetobacterium woodii
Published in International microbiology (01-08-2022)“…Methanol is one of the most widely produced organic substrates from syngas and can serve as a bio-feedstock to cultivate acetogenic bacteria which allows a…”
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A Na+ A1 AO ATP synthase with a V-type c subunit in a mesophilic bacterium
Published in The FEBS journal (01-07-2020)Get full text
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Mutational Analysis of Mycobacterial F‑ATP Synthase Subunit δ Leads to a Potent δ Enzyme Inhibitor
Published in ACS chemical biology (18-03-2022)“…While many bacteria are able to bypass the requirement for oxidative phosphorylation when grown on carbohydrates, Mycobacterium tuberculosis is unable to do…”
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