Search Results - "Litton, MJ"
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Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B
Published in Journal of immunological methods (30-09-1994)“…Excessive cytokine expression induced by superantigen may be one aspect of the pathophysiology associated with Gram positive bacteremia. We have undertaken a…”
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Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10
Published in The Journal of experimental medicine (01-08-1996)“…The mechanism by which the mammalian mother accepts the implanting fetus as an allograft remains unexplained, but is likely to be the result of a combination…”
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Cytokine production in synovial tissue of mice with collagen‐induced arthritis (CIA)
Published in Clinical and experimental immunology (01-03-1997)“…The kinetics of cytokine production in arthritic limbs of mice with CIA was determined by using modified immunohistochemical techniques. Tissue cryostat…”
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The distinct role of CD4 and CD8 T-cells during the anti-tumour effects of targeted superantigens
Published in British Journal of Cancer (01-09-1999)“…To target T-cells to the tumour area we created a recombinant protein of the bacterial superantigen (SAg) Staphylococcal enterotoxin A (SEA) and the…”
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Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma
Published in European journal of immunology (01-01-1996)“…Bacterial superantigens are the most potent known activators of human T lymphocytes. To engineer superantigens for immunotherapy of human colon carcinoma, the…”
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Genetically Engineered Superantigens as Tolerable Antitumor Agents
Published in Proceedings of the National Academy of Sciences - PNAS (18-03-1997)“…Superantigens (SAg) are a family of bacterial and viral proteins with strong immunostimulatory properties. SAg bound to major histocompatibility complex (MHC)…”
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Tumor therapy with an antibody-targeted superantigen generates a dichotomy between local and systemic immune responses
Published in The American journal of pathology (01-05-1997)“…Repeated injections of a fusion protein containing the superantigen staphylococcal enterotoxin A (SEA) combined with a Fab fragment of a tumor-specific…”
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Immunocytochemical Detection Of Cytokines In The Lymph Nodes And Brains Of Mice Resistant Or Susceptible To Toxoplasmic Encephalitis
Published in The Journal of infectious diseases (01-10-1994)“…BALB/c mice develop toxoplasmic encephalitis (TE) but the pathology resolves; in contrast, CBA/Ca mice develop progressive TE. Immunohistochemical analysis…”
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Antibody-targeted superantigens in cancer immunotherapy
Published in Immunotechnology (01-09-1996)Get full text
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