Search Results - "Litton, M. J."

Cytokine production in synovial tissue of mice with collagen‐induced arthritis (CIA) by MU¨SSENER, Å., LITTON, M. J., LINDROOS, E., KLARESKOG, L.

“…The kinetics of cytokine production in arthritic limbs of mice with CIA was determined by using modified immunohistochemical techniques. Tissue cryostat…”
Get full text

The distinct role of CD4 and CD8 T-cells during the anti-tumour effects of targeted superantigens by LITTON, M. J, DOHLSTEN, M, ROSENDAHL, A, OHLSSON, L, SØGAARD, M, ANDERSSON, J, ANDERSSON, U

“…To target T-cells to the tumour area we created a recombinant protein of the bacterial superantigen (SAg) Staphylococcal enterotoxin A (SEA) and the…”
Get full text

Tumor therapy with an antibody-targeted superantigen generates a dichotomy between local and systemic immune responses by Litton, MJ, Dohlsten, M, Hansson, J, Rosendahl, A, Ohlsson, L, Kalland, T, Andersson, J, Andersson, U

“…Repeated injections of a fusion protein containing the superantigen staphylococcal enterotoxin A (SEA) combined with a Fab fragment of a tumor-specific…”
Get full text

Early expression of cytokines in lymph nodes after treatment in vivo with Staphylococcus enterotoxin B by Litton, M J, Sander, B, Murphy, E, O'Garra, A, Abrams, J S

“…Excessive cytokine expression induced by superantigen may be one aspect of the pathophysiology associated with Gram positive bacteremia. We have undertaken a…”
Get more information

Immunocytochemical Detection Of Cytokines In The Lymph Nodes And Brains Of Mice Resistant Or Susceptible To Toxoplasmic Encephalitis by Hunter, c. A., Litton, M. J., Remington, J. S., Abrams, J. S.

“…BALB/c mice develop toxoplasmic encephalitis (TE) but the pathology resolves; in contrast, CBA/Ca mice develop progressive TE. Immunohistochemical analysis…”
Get full text

Human placental cytotrophoblasts produce the immunosuppressive cytokine interleukin 10 by Roth, I, Corry, D B, Locksley, R M, Abrams, J S, Litton, M J, Fisher, S J

“…The mechanism by which the mammalian mother accepts the implanting fetus as an allograft remains unexplained, but is likely to be the result of a combination…”
Get full text

Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma by Litton, M J, Dohlsten, M, Lando, P A, Kalland, T, Ohlsson, L, Andersson, J, Andersson, U

“…Bacterial superantigens are the most potent known activators of human T lymphocytes. To engineer superantigens for immunotherapy of human colon carcinoma, the…”
Get more information

Genetically Engineered Superantigens as Tolerable Antitumor Agents by Hansson, Johan, Ohlsson, Lennart, Persson, Robert, Andersson, Gunnar, Ilback, Nils-Gunnar, Litton, Mark J., Kalland, Terje, Dohlsten, Mikael

“…Superantigens (SAg) are a family of bacterial and viral proteins with strong immunostimulatory properties. SAg bound to major histocompatibility complex (MHC)…”
Get full text

Antibody-targeted superantigens in cancer immunotherapy by Søgaard, Morten, Hansson, Johan, Litton, Mark J., Ohlsson, Lennart, Rosendahl, Alexander, Lando, Peter A., Antonsson, Per, Kalland, Terje, Dohlsten, Mikael

Get full text