Search Results - "Littman, BH"

The ultimate model organism: progress in experimental medicine by Williams, Stephen A, Littman, Bruce H

“…Experimental medicine is the use of innovative measurements, models and designs in studying human subjects for establishing proof of mechanism and concept of…”
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What's next in translational medicine? by Littman, Bruce H, Di Mario, Linda, Plebani, Mario, Marincola, Francesco M

“…Translational medicine is the integrated application of innovative pharmacology tools, biomarkers, clinical methods, clinical technologies and study designs to…”
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Analysis of changes in acute-phase plasma proteins in an acute inflammatory response and in rheumatoid arthritis using two-dimensional gel electrophoresis by Doherty, N S, Littman, B H, Reilly, K, Swindell, A C, Buss, J M, Anderson, N L

“…Two-dimensional (2-D) gel analysis was used to examine differences in the levels of 19 plasma proteins: before and after an acute inflammatory reaction…”
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Linear scleroderma: a response to neurologic injury? Report and literature review by Littman, B H

“…A 28-year-old white man presented with neurologic symptoms and skin changes. Subsequent evaluation led to the diagnosis of transverse myelitis of the cervical…”
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The fibrinogenolytic activity of purified tryptase from human lung mast cells by Schwartz, LB, Bradford, TR, Littman, BH, Wintroub, BU

“…The capacity of purified tryptase from human lung mast cells to metabolize human fibrinogen, fibrin, and plasminogen was evaluated. Tryptase (5 micrograms/ml)…”
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Regulation of monocyte/macrophage C2 production and HLA-DR expression by IL-4 (BSF-1) and IFN-gamma by Littman, BH, Dastvan, FF, Carlson, PL, Sanders, KM

“…IL-4 was originally described on the basis of its ability to co-stimulate the proliferation of resting B cells treated with anti-IgM. Recently, this cytokine…”
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Steroid sparing activity of tenidap in patients with polymyalgia rheumatica: a multicenter double blind randomized placebo controlled study by Littman, B H, Bjarnason, D, Bryant, G, Engelbrecht, J, Cohen, M, Mertz, L, Weaver, A, Hunder, G G

“…To determine whether tenidap treatment would allow reduction or replacement of systemic corticosteroid treatment in patients with polymyalgia rheumatica (PMR)…”
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Production of the second component of complement by human monocytes: stimulation by antigen-activated lymphocytes or lymphokines by Littman, B H, Ruddy, S

“…Human peripheral blood mononuclear cells cultured in the presence of antigen produced hemolytically active second complement component earlier and in larger…”
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Lymphokine stimulation of human macrophage C2 production is partially due to interferon-gamma by Sanders, KM, Littman, BH

“…Monocyte complement stimulator (MCS), a product of T lymphocytes, is defined by its ability to stimulate the synthesis and secretion of the second complement…”
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Ibuprofen-Induced Meningitis in Systemic Lupus Erythematosus by Widener, Herbert L, Littman, Bruce H

“…A patient with systemic lupus erythematosus had chills, fever, and headache on four separate occasions after ibuprofen ingestion. One such episode was…”
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Effects of vitamin D3 and IFN-gamma on the synthesis of the second complement component, C2, by a human myeloid leukemia (HL-60) cell line by Littman, BH, Sanders, KM

“…HL-60 cells, a human promyelocytic cell line, can be induced to differentiate along either monocytic or granulocytic pathways. The production of the second…”
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Asymptomatic hyperuricemia. The case for benign neglect by Littman, B H

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Correlation of immunoglobulin and C reactive protein levels in ankylosing spondylitis and rheumatoid arthritis by Sanders, K M, Hertzman, A, Escobar, M R, Littman, B H

“…Serum C reactive protein (CRP), IgG, and IgA levels were measured in 22 patients with ankylosing spondylitis (AS) and in 20 patients with rheumatoid arthritis…”
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Gene expression (collagenase, tissue inhibitor of metalloproteinases, complement, and HLA-DR) in rheumatoid arthritis and osteoarthritis synovium. Quantitative analysis and effect of intraarticular corticosteroids by Firestein, G S, Paine, M M, Littman, B H

“…In situ hybridization was used to localize and quantify gene expression in rheumatoid arthritis (RA) and osteoarthritis (OA) synovial tissue. Collagenase,…”
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Monoclonal lupus autoantibody secretion by human-human hybridomas: selection of hybrids by conventional and novel techniques by LITTMAN, B. H, MUCHMORE, A. V, STEINBERG, A. D, GREENE, W. C

“…Autoantibody-secreting hybridomas were produced by somatic cell fusion of B lymphocytes from a patient with systemic lupus erythematosus with two different…”
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Lymphokine and phorbol (PMA) regulation of complement (C2) synthesis using U937 by Littman, B H, Hall, R E, Muchmore, A V

“…Human monocytes synthesize large amounts of the second complement component (C2) after incubation with a T-lymphocyte product called monocyte complement…”
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Migration inhibitory factor (MIF) and proliferative responses by human lymphocyte subpopulations separated by sheep erythrocyte rosette formation by Littman, B H, David, J R, Rocklin, R E

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Cell-mediated tumor immunity measured in vitro and in vivo with soluble tumor-specific antigens by Meltzer, M S, Oppenheim, J J, Littman, B H, Leonard, E J, Rapp, H J

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Gold inhibition of the production of the second complement component by lymphokine-stimulated human monocytes by Littman, B H, Schwartz, P

“…The ability of gold sodium thiomalate to inhibit production of the second complement component (C2) by monocytes stimulated by a lymphokine (monocyte…”
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Rheumatoid arthritis treated with tenidap and piroxicam. Clinical associations with cytokine modulation by tenidap by Littman, B H, Drury, C E, Zimmerer, R O, Stack, C B, Law, C G

“…To compare the effects of tenidap and piroxicam on acute-phase protein and cytokine levels in the blood of rheumatoid arthritis (RA) patients and to explore…”
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