Search Results - "Littlefield, Ethel S"

Rational design of azepane-glycoside antibiotics targeting the bacterial ribosome by Barluenga, Sofia, Simonsen, Klaus B., Littlefield, Ethel S., Ayida, Benjamin K., Vourloumis, Dionisios, Winters, Geoffrey C., Takahashi, Masayuki, Shandrick, Sarah, Zhao, Qiang, Han, Qing, Hermann, Thomas

“…RNA recognition by natural aminoglycoside antibiotics depends on the 2-deoxystreptamine (2-DOS) scaffold which participates in specific hydrogen bonds with the…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 1. Michael Acceptor Structure−Activity Studies by Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Lee, Caroline A, Reich, Siegfried H, Prins, Thomas J, Marakovits, Joseph T, Littlefield, Ethel S, Zhou, Ru, Tikhe, Jayashree, Ford, Clifford E, Wallace, Michael B, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, Harr, James E. V, DeLisle, Dorothy M, Worland, Stephen T

“…The structure-based design, chemical synthesis, and biological evaluation of peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are described…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies by Dragovich, Peter S, Webber, Stephen E, Babine, Robert E, Fuhrman, Shella A, Patick, Amy K, Matthews, David A, Reich, Siegfried H, Marakovits, Joseph T, Prins, Thomas J, Zhou, Ru, Tikhe, Jayashree, Littlefield, Ethel S, Bleckman, Ted M, Wallace, Michael B, Little, Thomas L, Ford, Clifford E, Meador, James W, Ferre, Rose Ann, Brown, Edward L, Binford, Susan L, DeLisle, Dorothy M, Worland, Stephen T

“…The structure-based design, chemical synthesis, and biological evaluation of various peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are…”
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Comparison of desmethylsertraline with sertraline as a monoamine uptake inhibitor in vivo by Fuller, Ray W., Hemrick-Luecke, Susan K., Littlefield, Ethel S., Audia, James E.

“…1. 1. Desmethylsertraline, a metabolite of the antidepressant drug sertraline, was compared with sertraline for its ability to produce effects characteristic…”
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Design, synthesis and X-ray crystallographic studies of [7.3.1] and [8.3.1] macrocyclic FKBP-12 ligands by Babine, Robert E., Bleckman, T.M., Littlefield, Ethel S., Parge, Hans E., Pelletier, L.A.K., Lewis, Cristina T., French, Judy V., Imbacuan, Michael, Katoh, Susumo, Tatlock, John H., Showalter, Richard E., Villafranca, J.Ernest

“…The design, synthesis, and structure activity relationships of a series of novel macrocyclic FKBP-12 ligands 1 are reported. The crystal structure of the…”
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