Search Results - "Little, Thomas L"
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A Simple and Practical Synthesis of 2-Aminoimidazoles
Published in Journal of organic chemistry (01-12-1994)Get full text
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Tripeptide Aldehyde Inhibitors of Human Rhinovirus 3C Protease: Design, Synthesis, Biological Evaluation, and Cocrystal Structure Solution of P1 Glutamine Isosteric Replacements
Published in Journal of medicinal chemistry (16-07-1998)“…The investigation of tripeptide aldehydes as reversible covalent inhibitors of human rhinovirus (HRV) 3C protease (3CP) is reported. Molecular models based on…”
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Analogs of poison ivy urushiol. Synthesis and biological activity of disubstituted n-alkylbenzenes
Published in Journal of medicinal chemistry (01-05-1986)“…The total synthesis of different isomers and analogues of poison ivy urushiol is described. These include the positional isomers 1-5 and the…”
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Metabolism of phencyclidine. The role of the carbinolamine intermediate in the formation of lactam and amino acid metabolites of nitrogen heterocycles
Published in Journal of medicinal chemistry (01-01-1985)“…The transformation of phencyclidine in a mouse liver microsome preparation to several oxidative metabolites was studied. With use of GLC and HPLC methods with…”
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GC/MS analysis of phencyclidine acid metabolite in human urine
Published in Journal of analytical toxicology (01-07-1988)“…Available methods for determining PCP use are based on the presence of the parent drug in urine. PCP, however, is very potent and is extensively metabolized;…”
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Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 2. Peptide Structure−Activity Studies
Published in Journal of medicinal chemistry (16-07-1998)“…The structure-based design, chemical synthesis, and biological evaluation of various peptide-derived human rhinovirus (HRV) 3C protease (3CP) inhibitors are…”
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Rectal bioavailability of delta-9-tetrahydrocannabinol from the hemisuccinate ester in monkeys
Published in Journal of pharmaceutical sciences (01-10-1991)“…Oral administration of delta-9-tetrahydrocannabinal (delta 9-THC) was shown to result in low and erratic bioavailability, while the drug showed no…”
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Rectal bioavailability of delta-9-tetrahydrocannabinol from various esters
Published in Pharmacology, biochemistry and behavior (01-11-1991)“…The bioavailability of delta-9-tetrahydrocannabinol (delta 9-THC) from suppository formulations containing several polar esters was studied. The esters tested…”
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The Teacher-Consultant Model--A Different Perspective: A Reaction to Symposium 13
Published in Journal of Special Education (1978)“…The article reacts to and expands a symposium on the desirability of a transition from the traditional diagnostic-remedial model to the teacher-consultant…”
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Training Special Education Support Personnel
Published in Teacher Educator (1977)“…University preparation programs must be developed for the instruction of educational support personnel for teachers who are operating in special education…”
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2H6-11-nor-delta-8-thc-9-COOH: a new internal standard for the analysis of THC metabolite in biological fluids
Published in Journal of analytical toxicology (01-01-1988)Get more information
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Stability of methadone pain cocktails
Published in American journal of hospital pharmacy (01-04-1982)Get more information
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Continuity of care and poisoning prevention education
Published in Patient counselling and health education (01-01-1980)Get more information
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