Search Results - "Little, P.F.R."

Disruption of a Novel Imprinted Zinc-Finger Gene, ZNF215, in Beckwith-Wiedemann Syndrome by Alders, M., Ryan, A., Hodges, M., Bliek, J., Feinberg, A.P., Privitera, O., Westerveld, A., Little, P.F.R., Mannens, M.

“…The genetics of Beckwith-Wiedemann syndrome (BWS) is complex and is thought to involve multiple genes. It is known that three regions on chromosome 11p15 (…”
Get full text

Molecular Medicine by Little, P.F.R

Get full text

Sequencing techniques: A close look at the genome by Little, P.F.R

Get full text

Tumor Cell Growth Arrest Caused by Subchromosomal Transferable DNA Fragments from Chromosome 11 by Koi, Minoru, Johnson, Laura A., Kalikin, Linda M., Peter F. R. Little, Nakamura, Yusuke, Feinberg, Andrew P.

“…A fundamental problem in the identification and isolation of tumor suppressor and other growth-inhibiting genes is the loss of power of genetic complementation…”
Get full text

High-resolution localization of 69 potential human zinc finger protein genes: a number are clustered by Hoovers, J M, Mannens, M, John, R, Bliek, J, van Heyningen, V, Porteous, D J, Leschot, N J, Westerveld, A, Little, P F

“…In this study, we describe the identification and partial characterization of 101 potential human zinc finger protein genes (ZnFPs). These sequences were…”
Get more information

Human nicotinamide N-methyltransferase gene : molecular cloning, structural characterization and chromosomal localization by AKSOY, S, BRANDRIFF, B. F, WARD, A, LITTLE, P. F. R, WEINSHILBOUM, R. M

“…Genomic DNA clones for nicotinamide N-methyltransferase (NNMT), an enzyme that catalyzes drug and xenobiotic metabolism, were isolated from a human chromosome…”
Get full text

The flamingo-related mouse Celsr family ( Celsr1– 3) genes exhibit distinct patterns of expression during embryonic development by Formstone, C.J., Little, P.F.R.

“…We have isolated cDNAs for three members of a family of seven-pass transmembrane cadherins in mouse ( Celsr1, 2 and 3). These three genes represent vertebrate…”
Get full text

A Sequence-Ready 3-Mb PAC Contig Covering 16 Breakpoints of the Wilms Tumor/Anirida Region of Human Chromosome 11p13 by Niederführ, A., Hummerich, H., Gawin, B., Boyle, S., Little, P.F.R., Gessler, M.

“…A large body of evidence that links alterations of chromosome 11p13 to tumor formation and various developmental disorders has been accumulated. To address the…”
Get full text

Genomic Organization and Chromosomal Localization of a Member of the MAP Kinase Phosphatase Gene Family to Human Chromosome 11p15.5 and a Pseudogene to 10q11.2 by Nesbit, M.A., Hodges, M.D., Campbell, L., de Meulemeester, T.M.A.M.O., Alders, M., Rodrigues, N.R., Talbot, K., Theodosiou, A.M., Mannens, M.A., Nakamura, Y., Little, P.F.R., Davies, K.E.

“…Mitogen-activated protein kinase phosphatases (MKPs) play a central role in a variety of signaling pathways. We recently described a novel murine MKP, M3/6,…”
Get full text

An integrated physical map of 210 markers assigned to the short arm of human chromosome 11 by Redeker, E, Hoovers, J M, Alders, M, van Moorsel, C J, Ivens, A C, Gregory, S, Kalikin, L, Bliek, J, de Galan, L, van den Bogaard, R

“…Using a panel of patient cell lines with chromosomal breakpoints, we constructed a physical map for the short arm of human chromosome 11. We focused on 11p15,…”
Get more information

Molecular organisation of an A mating type factor of the basidiomycete fungus Coprinus cinereus by Mutasa, E.S, Tymon, A.M, Gottgens, B, Mellon, F.M, Little, P.F.R, Casselton, L.A

“…The A alpha 3 and A beta 3 genes, which together constitute the A42 mating type factor of Coprinus cinereus , were isolated from a cosmid genomic library by…”
Get full text

Gene mapping and the human genome mapping project by Little, P F

Get more information

A cosmid vector for systematic chromosome walking by Cross, S H, Little, P F

“…We describe the construction of a cosmid, LoristB, that contains SP6 and T7 phage-encoded RNA polymerase promoter sequences that are oriented towards and…”
Get more information

Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: direct determination of gene linkage and intergene distance by Flavell, R A, Kooter, J M, De Boer, E, Little, P F, Williamson, R

“…Total human DNA was cleaved with a variety of restriction enzymes, and the fragments were fractionated by gel electrophoresis and transferred to nitrocellulose…”
Get more information

Seven genes on the short arm of human chromosome 3 map to two regions on Macropus eugenii (tammar wallaby) chromosome 2 by Miller, D A, Miller, O J, Francis, D, Little, P F, Graves, J A

“…Seven genes were mapped by in situ hybridization to metaphase chromosomes of the marsupial species Macropus eugenii, using a series of human-derived cloned…”
Get more information

A cosmid clone map derived from a small region of human chromosome 11 by Harrison-Lavoie, K J, John, R M, Porteous, D J, Little, P F

“…We have used cosmid "fingerprinting" to construct an overlapping DNA clone "map" of the human DNA in a mouse/human hybrid cell line, E65-9, that contains about…”
Get more information

Physical and genetic analysis of cosmids from the vicinity of the cystic fibrosis locus by SCAMBLER, P. J, ESTIVILL, X, LENCH, N. J, BELL, G, FARRALL, M, MCLEAN, C, LITTLE, P. F. R, FREDERICK, P, HAWLEY, K, WAINWRIGHT, B. J, WILLIAMSON, R

“…Cosmid libraries have been constructed from DNA of somatic cell hybrid cell lines, each containing a fragment of human chromosome seven and including sequences…”
Get full text

The structure of the human β-globin gene in β-thalassaemia by Flavell, R.A., Bernards, R., Kooter, J.M., de Boer, E., Little, P.F.R., Annison, G., Williamson, R.

“…Twenty-one cases of β0- and β+ -thalassaemia have been analysed by restriction endonuclease mapping. In most cases no deletion in the regions surrounding the…”
Get full text