Search Results - "Little, Nathaniel"
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Epidermal Growth Factor Receptor Controls Flat Dysplastic Aberrant Crypt Foci Development and Colon Cancer Progression in the Rat Azoxymethane Model
Published in Clinical cancer research (15-04-2008)“…Purpose: Colonic carcinogenesis deranges growth-regulating epidermal growth factor receptors (EGFR). We previously showed that EGFR signals were up-regulated…”
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A Vitamin D Analogue Inhibits Colonic Carcinogenesis in the AOM/DSS Model
Published in The Journal of surgical research (01-10-2007)“…Background The azoxymethane (AOM) model recapitulates many features of human colon cancer, lacking an inflammatory component. Dextran sulfate sodium (DSS)…”
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Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis
Published in Cancer research (Chicago, Ill.) (15-01-2007)“…Colonic carcinogenesis involves the progressive dysregulation of homeostatic mechanisms that control growth. The epidermal growth factor (EGF) receptor (EGFR)…”
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Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci
Published in Cancer research (Chicago, Ill.) (01-06-2006)“…Aberrant crypt foci (ACF) are collections of abnormal colonic crypts with heterogeneous molecular and pathologic characteristics. Large and dysplastic ACF are…”
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Abstract IA13: In the light of evolution: Why do we get more cancers in old age?
Published in Cancer research (Chicago, Ill.) (01-11-2020)“…Abstract Why do we get cancer? Why is cancer highly associated with old age? Of course, aging is associated with the accumulation of more mutations, and some…”
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Maximizing Benefits and Minimizing Harms of Lung Cancer Screening: A Teachable Moment
Published in JAMA internal medicine (01-08-2017)Get more information
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Abstract A026: Altered immune landscape in aging lungs contributes to malignant evolution
Published in Cancer research (Chicago, Ill.) (15-05-2022)“…Abstract Aging is a major risk factor in increased lung cancer incidence. While most research has focused on age-associated mutation accumulation to explain…”
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Refractory Cardiogenic Shock from Right Ventricular Infarction Successfully Managed with Inhaled Epoprostenol
Published in The American journal of case reports (16-03-2017)“…BACKGROUND Recognition and appropriate management of right ventricular (RV) infarction is essential, as RV injury increases mortality and substantially alters…”
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