Search Results - "Little, B. J."

Low-dose radiation exposure induces a HIF-1-mediated adaptive and protective metabolic response by Lall, R, Ganapathy, S, Yang, M, Xiao, S, Xu, T, Su, H, Shadfan, M, Asara, J M, Ha, C S, Ben-Sahra, I, Manning, B D, Little, J B, Yuan, Z-M

“…Because of insufficient understanding of the molecular effects of low levels of radiation exposure, there is a great uncertainty regarding its health risks. We…”
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Radiation carcinogenesis by LITTLE, J. B

“…Research on radiation carcinogenesis during the past 2 decades has focused on cellular and molecular mechanisms for the effects of radiation in mammalian…”
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Diagnosing microbiologically influenced corrosion : A state-of-the-art review by LITTLE, B. J, LEE, J. S, RAY, R. I

“…Diagnosing microbiotogically influenced corrosion (MIC) after it has occurred requires a combination of microbiological, metallurgical, and chemical analyses…”
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The Bystander Effect in Radiation Oncogenesis: II. A Quantitative Model by Brenner, D. J., Little, J. B., Sachs, R. K.

“…Brenner, D. J., Little, J. B. and Sachs, R. K. The Bystander Effect in Radiation Oncogenesis: II. A Quantitative Model. There is strong evidence that…”
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Technical Note: Influence of Experimental Conditions on the Outcome of Laboratory Investigations Using Natural Coastal Seawaters by LEE, J. S, RAY, R. I, LITTLE, B. J

“…Methods for handling and storing natural coastal seawater, particularly methods for deaeration over time, influenced the chemistry and microflora. Bubbling…”
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Increased bystander mutagenic effect in DNA double-strand break repair-deficient mammalian cells by Nagasawa, H., Huo, L., Little, J. B.

“…Purpose : We have shown previously that when monolayer cultures of Chinese hamster ovary (CHO) cells are exposed to very low fluences of alpha-particles, HPRT…”
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Radiation-induced genomic instability by LITTLE, J. B.

“…Purpose: This report reviews the data obtained in the author's laboratory over the past two decades, which support the hypothesis that radiation can induce a…”
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Induction of sister chromatid exchanges by extremely low doses of α-particles by NAGASAWA, H, LITTLE, J. B

“…The induction of sister chromatid exchanges (SCE) was examined in Chinese hamster ovary cells irradiated in the G1 phase of the cell cycle with alpha-particles…”
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Bystander Effects: Intercellular Transmission of Radiation Damage Signals by LITTLE, J. B, AZZAM, E. I, DE TOLEDO, S. M, NAGASAWA, H

“…Biological effects were examined in confluent cultures of fibroblasts and epithelial cells exposed to very low mean doses of alpha radiation, doses by which…”
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Unexpected Sensitivity to the Induction of Mutations by Very Low Doses of Alpha-Particle Radiation: Evidence for a Bystander Effect by Nagasawa, Hatsumi, Little, John B.

“…We examined the induction of HPRT mutations in CHO cells exposed to low fluences of ^{238}{\rm Pu}$ α particles from a specially constructed irradiator. The…”
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Intercellular Communication Is Involved in the Bystander Regulation of Gene Expression in Human Cells Exposed to Very Low Fluences of Alpha Particles by Azzam, Edouard I., de Toledo, Sonia M., Gooding, Tamara, Little, John B.

“…We demonstrate by western analysis that the expression levels of TP53 (formerly known as p53), CDKN1A (formerly known as ${\rm p}21^{{\rm Waf1}}$), CDC2…”
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Can Dynamic Bubble Templating Play a Role in Corrosion Product Morphology? by GERKE, T. L, SCHECKEL, K. G, RAY, R. I, LITTLE, B. J

“…Dynamic templating as a result of cathodic hydrogen gas production is suggested as a possible mechanism for the formation of tube-like corrosion products on an…”
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Relationship Between Corrosion and the Biological Sulfur Cycle: A Review by Little, B.J., Ray, R.I., Pope, R.K.

“…ABSTRACTMost microbiologically influenced corrosion (MIC) takes place in the presence of microbial consortia in which many different physiological types of…”
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Role of Homologous Recombination in the Alpha-Particle-Induced Bystander Effect for Sister Chromatid Exchanges and Chromosomal Aberrations by Nagasawa, H., Peng, Y., Wilson, P. F., Lio, Y-C., Chen, D. J., Bedford, J. S., Little, J. B.

“…Nagasawa, H., Peng, Y., Wilson, P. F., Lio, Y-C., Chen, D. J., Bedford, J. S. and Little, J. B. Role of Homologous Recombination in the Alpha-Particle-Induced…”
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Regulation of normal cell cycle progression by flavin-containing oxidases by Venkatachalam, P, de Toledo, S M, Pandey, B N, Tephly, L A, Carter, A B, Little, J B, Spitz, D R, Azzam, E I

“…Mechanisms underlying the role of reactive oxygen species (ROS) generated by flavin-containing oxidases in regulating cell cycle progression were examined in…”
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HPRT Mutants Induced in Bystander Cells by Very Low Fluences of Alpha Particles Result Primarily from Point Mutations by Huo, Lihong, Nagasawa, Hatsumi, Little, John B.

“…Huo, L., Nagasawa, H. and Little, J. B. HPRT Mutants Induced in Bystander Cells by Very Low Fluences of Alpha Particles Result Primarily from Point Mutations…”
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Microbially influenced corrosion—Any progress? by Little, B.J., Blackwood, D.J., Hinks, J., Lauro, F.M., Marsili, E., Okamoto, A., Rice, S.A., Wade, S.A., Flemming, H.-C.

“…•After over 50 years, research has failed to answer fundamental questions related to MIC.•Research has not provided tools for detection of MIC in the…”
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Low dose ionizing radiation-induced activation of connexin 43 expression by Glover, D., Little, J. B., Lavin, M. F., Gueven, N.

“…Purpose: Connexin 43 has been implicated in the cellular response to ionizing radiation by enabling cell-to-cell communication. It is established here that the…”
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Radiation-Induced Genomic Instability: Delayed Mutagenic and Cytogenetic Effects of X Rays and Alpha Particles by Little, John B., Nagasawa, Hatsumi, Pfenning, Tracy, Vetrovs, Helen

“…The frequency of mutations at the Hprt locus was measured in clonal populations of Chinese hamster ovary cells derived from single cells surviving exposure to…”
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Evaluation of Deoxygenation as a Corrosion Control Measure for Ballast Tanks by Lee, J.S., Ray, R.I., Little, B.J., Lemieux, E.J.

“…ABSTRACTField experiments designed to evaluate deoxygenation of natural seawater as a corrosion control measure for unprotected carbon steel seawater ballast…”
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