Search Results - "Lithgo, Ryan"

Defining the mechanism of galectin-3–mediated TGF-β1 activation and its role in lung fibrosis by Calver, Jessica F., Parmar, Nimesh R., Harris, Gemma, Lithgo, Ryan M., Stylianou, Panayiota, Zetterberg, Fredrik R., Gooptu, Bibek, Mackinnon, Alison C., Carr, Stephen B., Borthwick, Lee A., Scott, David J., Stewart, Iain D., Slack, Robert J., Jenkins, R. Gisli, John, Alison E.

“…Integrin-mediated activation of the profibrotic mediator transforming growth factor-β1 (TGF-β1), plays a critical role in idiopathic pulmonary fibrosis (IPF)…”
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The adaptability of the ion-binding site by the Ag(I)/Cu(I) periplasmic chaperone SilF by Lithgo, Ryan M, Hanževački, Marko, Harris, Gemma, Kamps, Jos J A G, Holden, Ellie, Gianga, Tiberiu-Marius, Benesch, Justin L P, Jäger, Christof M, Croft, Anna K, Hussain, Rohannah, Hobman, Jon L, Orville, Allen M, Quigley, Andrew, Carr, Stephen B, Scott, David J

“…The periplasmic chaperone SilF has been identified as part of an Ag(I) detoxification system in Gram-negative bacteria. Sil proteins also bind Cu(I) but with…”
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The antibiotic vancomycin induces complexation and aggregation of gastrointestinal and submaxillary mucins by Dinu, Vlad, Lu, Yudong, Weston, Nicola, Lithgo, Ryan, Coupe, Hayley, Channell, Guy, Adams, Gary G., Torcello Gómez, Amelia, Sabater, Carlos, Mackie, Alan, Parmenter, Christopher, Fisk, Ian, Phillips-Jones, Mary K., Harding, Stephen E.

“…Vancomycin, a branched tricyclic glycosylated peptide antibiotic, is a last-line defence against serious infections caused by staphylococci, enterococci and…”
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Full hydrodynamic reversibility of the weak dimerization of vancomycin and elucidation of its interaction with VanS monomers at clinical concentration by Phillips-Jones, Mary K., Lithgo, Ryan, Dinu, Vlad, Gillis, Richard B., Harding, John E., Adams, Gary G., Harding, Stephen E.

“…The reversibility and strength of the previously established dimerization of the important glycopeptide antibiotic vancomycin in four different aqueous…”
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Changes in Membrane Protein Structural Biology by Birch, James, Cheruvara, Harish, Gamage, Nadisha, Harrison, Peter J, Lithgo, Ryan, Quigley, Andrew

“…Membrane proteins are essential components of many biochemical processes and are important pharmaceutical targets. Membrane protein structural biology provides…”
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Characterisation of insulin analogues therapeutically available to patients by Adams, Gary G, Meal, Andrew, Morgan, Paul S, Alzahrani, Qushmua E, Zobel, Hanne, Lithgo, Ryan, Kok, M Samil, Besong, David T M, Jiwani, Shahwar I, Ballance, Simon, Harding, Stephen E, Chayen, Naomi, Gillis, Richard B

“…The structure and function of clinical dosage insulin and its analogues were assessed. This included 'native insulins' (human recombinant, bovine, porcine),…”
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Exploring the Molecular Mechanisms of Ag(I) Transporters Involved in Bacterial Ag(I) Resistance by Lithgo, Ryan

“…Silver (Ag(I)) displays multiple antimicrobial properties that have led to its widespread use in the medical field. However, extensive use of Ag(I) has led to…”
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Flavour compounds affect protein structure: The effect of methyl anthranilate on bovine serum albumin conformation by Dinu, Vlad, Borah, Pallab Kumar, Muleya, Molly, Scott, David J, Lithgo, Ryan, Pattem, Jacob, Harding, Stephen E., Yakubov, Gleb E., Fisk, Ian D.

“…•The binding of methyl anthranilate with bovine serum albumin (BSA) was investigated.•Methyl anthranilate binds to BSA, resulting in protein…”
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