Search Results - "Litersky, J M"

Phosphorylation by cAMP-dependent protein kinase inhibits the degradation of tau by calpain by Litersky, J M, Johnson, G V

“…The effects of cAMP-dependent protein kinase (cAMP-PK) phosphorylation on the degradation of the microtubule-associated protein tau by calpain were studied…”
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Phosphorylation of Tau by Fyn: Implications for Alzheimer's Disease by Lee, Gloria, Thangavel, Ramasamy, Sharma, Vandana M, Litersky, Joel M, Bhaskar, Kiran, Fang, Sandy M, Do, Lana H, Andreadis, Athena, Van Hoesen, Gary, Ksiezak-Reding, Hanna

“…The abnormal phosphorylation of tau protein on serines and threonines is a hallmark characteristic of the neurofibrillary tangles of Alzheimer's disease (AD)…”
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The interrelationship between selective tau phosphorylation and microtubule association by Xie, Han-qing, Litersky, Joel M, Hartigan, Judith A, Jope, Richard S, Johnson, Gail V.W

“…The purpose of this study was to examine the modulation of tau phosphorylation mediated by protein kinase A, a kinase with low intrinsic activity, and by the…”
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Degradation of microtubule-associated protein 2 and brain spectrin by calpain: a comparative study by Johnson, G V, Litersky, J M, Jope, R S

“…The in vitro degradation of microtubule-associated protein 2 (MAP-2) and spectrin by the calcium-dependent neutral protease calpain was studied. Five major…”
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Phosphorylation of tau in situ: inhibition of calcium-dependent proteolysis by Litersky, J M, Johnson, G V

“…In this study, the in situ phosphorylation and subsequent calcium-activated proteolysis of tau protein were examined in human neuroblastoma (LA-N-5) cells,…”
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Phosphorylation, calpain proteolysis and tubulin binding of recombinant human tau isoforms by Litersky, J M, Scott, C W, Johnson, G V

“…In this study, the phosphorylation, calpain hydrolysis and tubulin binding of three recombinant human tau isoforms were examined. The three isoforms used in…”
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Proteolysis of microtubule-associated protein 2 and tubulin by cathepsin D by Johnson, G V, Litersky, J M, Whitaker, J N

“…The in vitro degradation of microtubule-associated protein 2 (MAP-2) and tubulin by the lysosomal aspartyl endopeptidase cathepsin D was studied. MAP-2 was…”
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Tau protein is phosphorylated by cyclic AMP-dependent protein kinase and calcium/calmodulin-dependent protein kinase II within its microtubule-binding domains at Ser-262 and Ser-356 by Litersky, J M, Johnson, G V, Jakes, R, Goedert, M, Lee, M, Seubert, P

“…Phosphorylation of tau protein at Ser-262 has been shown to diminish its ability to bind to taxol-stabilized microtubules. The paired helical filaments (PHFs)…”
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Detection of Phosphorylated Ser in Fetal Tau, Adult Tau, and Paired Helical Filament Tau by Peter Seubert, Madhumalti Mawal-Dewan, Robin Barbour, Ross Jakes, Michel Goedert, Gail V. W. Johnson, Joel M. Litersky, Dale Schenk, Ivan Lieberburg, John Q. Trojanowski, Virginia M.-Y. Lee

“…Paired helical filaments (PHFs) are the major structural elements of Alzheimer's disease neurofibrillary lesions, and these filaments are formed from…”
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Detection of phosphorylated Ser super(262) in fetal tau, adult tau, and paired helical filament tau by Seubert, P, Mawal-Dewan, M, Barbour, R, Jakes, R, Goedert, M, Johnson, GVW, Litersky, J M, Schenk, D, Lieberburg, I, Trojanowski, J Q, Lee, VM-Y

“…Paired helical filaments (PHFs) are the major structural elements of Alzheimer's disease neurofibrillary lesions, and these filaments are formed from…”
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Detection of Phosphorylated Ser262 in Fetal Tau, Adult Tau, and Paired Helical Filament Tau (∗) by Seubert, Peter, Mawal-Dewan, Madhumalti, Barbour, Robin, Jakes, Ross, Goedert, Michel, Johnson, Gail V.W., Litersky, Joel M., Schenk, Dale, Lieberburg, Ivan, Trojanowski, John Q., Lee, Virginia M.-Y.

“…Paired helical filaments (PHFs) are the major structural elements of Alzheimer's disease neurofibrillary lesions, and these filaments are formed from…”
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