Search Results - "Litak, Jakub"
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1
PD-L1/PD-1 Axis in Glioblastoma Multiforme
Published in International journal of molecular sciences (28-10-2019)“…Glioblastoma (GBM) is the most popular primary central nervous system cancer and has an extremely expansive course. Aggressive tumor growth correlates with…”
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2
Cerebral Small Vessel Disease
Published in International journal of molecular sciences (20-12-2020)“…Cerebral small vessel disease (CSVD) represents a cluster of various vascular disorders with different pathological backgrounds. The advanced vasculature net…”
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3
Aquaporins: Gatekeepers of Fluid Dynamics in Traumatic Brain Injury
Published in International journal of molecular sciences (01-06-2024)“…Aquaporins (AQPs), particularly AQP4, play a crucial role in regulating fluid dynamics in the brain, impacting the development and resolution of edema…”
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4
Metformin as Potential Therapy for High-Grade Glioma
Published in Cancers (15-01-2020)“…Metformin (MET), 1,1-dimethylbiguanide hydrochloride, is a biguanide drug used as the first-line medication in the treatment of type 2 diabetes. The recent…”
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5
Hydroxyapatite Use in Spine Surgery-Molecular and Clinical Aspect
Published in Materials (15-04-2022)“…Hydroxyapatite possesses desirable properties as a scaffold in tissue engineering: it is biocompatible at a site of implantation, and it is degradable to…”
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6
Recent Trends of microRNA Significance in Pediatric Population Glioblastoma and Current Knowledge of Micro RNA Function in Glioblastoma Multiforme
Published in International journal of molecular sciences (27-04-2020)“…Central nervous system tumors are a significant problem for modern medicine because of their location. The explanation of the importance of microRNA (miRNA) in…”
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7
TLR-4 Signaling vs. Immune Checkpoints, miRNAs Molecules, Cancer Stem Cells, and Wingless-Signaling Interplay in Glioblastoma Multiforme-Future Perspectives
Published in International journal of molecular sciences (28-04-2020)“…Toll-like-receptor (TLR) family members were detected in the central nervous system (CNS). TLR occurrence was noticed and widely described in…”
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8
Low-Cost Cranioplasty-A Systematic Review of 3D Printing in Medicine
Published in Materials (06-07-2022)“…The high cost of biofabricated titanium mesh plates can make them out of reach for hospitals in low-income countries. To increase the availability of…”
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Micro RNA Molecules as Modulators of Treatment Resistance, Immune Checkpoints Controllers and Sensitive Biomarkers in Glioblastoma Multiforme
Published in International journal of molecular sciences (22-02-2020)“…Based on genome sequencing, it is estimated that over 90% of genes stored in human genetic material are transcribed, but only 3% of them contain the…”
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10
Aquaporin 2 in Cerebral Edema: Potential Prognostic Marker in Craniocerebral Injuries
Published in International journal of molecular sciences (01-06-2024)“…Despite continuous medical advancements, traumatic brain injury (TBI) remains a leading cause of death and disability worldwide. Consequently, there is a…”
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11
Metallic Implants Used in Lumbar Interbody Fusion
Published in Materials (20-05-2022)“…Over the last decade, pedicle fixation systems have evolved and modifications in spinal fusion techniques have been developed to increase fusion rates and…”
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12
Molecular Mechanisms and Clinical Application of Multipotent Stem Cells for Spinal Cord Injury
Published in Cells (Basel, Switzerland) (28-12-2022)“…Spinal Cord Injury (SCI) is a common neurological disorder with devastating psychical and psychosocial sequelae. The majority of patients after SCI suffer from…”
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13
Increased Aluminum Content in Certain Brain Structures is Correlated with Higher Silicon Concentration in Alcoholic Use Disorder
Published in Molecules (Basel, Switzerland) (03-05-2019)“…Alcohol overuse may be related to increased aluminum (Al) exposure, the brain accumulation of which contributes to dementia. However, some reports indicate…”
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14
Correlations Between Trace Elements in Selected Locations of the Human Brain in Individuals with Alcohol Use Disorder
Published in Molecules (Basel, Switzerland) (15-01-2020)“…Trace element distribution varies in different locations of the human brain. Several elements were found to cause various negative effects, such as…”
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15
New Horizons for Hydroxyapatite Supported by DXA Assessment-A Preliminary Study
Published in Materials (26-01-2022)“…Dual Energy X-ray Absorptiometry (DXA) is a tool that allows the assessment of bone density. It was first presented by Cameron and Sorenson in 1963 and was…”
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16
Initial Factors Affecting 6-month Outcome of Patients Undergoing Surgery for Acute Post-traumatic Subdural and Epidural Hematoma
Published in Folia Medica (31-03-2020)“…Introduction: The most frequent consequences of a traumatic brain injury are acute subdural (SDH) and epidural hematoma (EDH), which usually require a surgical…”
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17
Astroglial Cells: Emerging Therapeutic Targets in the Management of Traumatic Brain Injury
Published in Cells (Basel, Switzerland) (01-01-2024)“…Traumatic Brain Injury (TBI) represents a significant health concern, necessitating advanced therapeutic interventions. This detailed review explores the…”
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18
Diagnostic and Therapeutic Insights into Spinal Glomangioma of a Unique Intradural, Extramedullary Presentation-Systematic Review
Published in Diseases (20-06-2024)“…Contemporary literature lacks examples of intradural, extramedullary spinal glomangiomas. Moreover, glomus tumors in general are exceedingly rare among benign…”
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The Initial Factors with Strong Predictive Value in Relation to Six-Month Outcome among Patients Operated due to Extra-Axial Hematomas
Published in Diagnostics (Basel) (23-03-2020)“…Traumatic brain injuries (TBI) are a real social problem, with an upward trend worldwide. The most frequent consequence of a traumatic brain injury is…”
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PD-L1 Expression Correlated with p53 Expression in Pediatric Glioblastoma Multiforme
Published in Brain sciences (19-02-2021)“…High-grade gliomas are infrequent in the pediatric population compared to adults, nevertheless, mortality and morbidity caused by malignant gliomas in this…”
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