Search Results - "Lisle, Jessica E."

Evidence for a dual function of EphB4 as tumor promoter and suppressor regulated by the absence or presence of the ephrin-B2 ligand by Rutkowski, Raphael, Mertens-Walker, Inga, Lisle, Jessica E., Herington, Adrian C., Stephenson, Sally-Anne

“…Overexpression of the receptor tyrosine kinase EphB4 is common in epithelial cancers and linked to tumor progression by promoting angiogenesis, increasing…”
Get full text

Eph receptors and their ligands: Promising molecular biomarkers and therapeutic targets in prostate cancer by Lisle, Jessica E., Mertens-Walker, Inga, Rutkowski, Raphael, Herington, Adrian C., Stephenson, Sally-Anne

“…Although at present, there is a high incidence of prostate cancer, particularly in the Western world, mortality from this disease is declining and occurs…”
Get full text

Cell-Extrinsic Differentiation Block Mediated by EphA3 in Pre-Leukaemic Thymus Contributes to Disease Progression by Pliego Zamora, Adriana C., Ranasinghe, Hansini, Lisle, Jessica E., Ng, Chun Ki, Huang, Stephen, Wadlow, Racheal, Scott, Andrew M., Boyd, Andrew W., Slape, Christopher I.

“…We recently characterised the NUP98-HOXD13 (NHD13) mouse as a model of T-cell pre-leukaemia, featuring thymocytes that can engraft in recipient animals and…”
Get full text

Anti-tumour effects of antibodies targeting the extracellular cysteine-rich region of the receptor tyrosine kinase EphB4 by Stephenson, Sally-Anne, Douglas, Evelyn L, Mertens-Walker, Inga, Lisle, Jessica E, Maharaj, Mohanan S N, Herington, Adrian C

“…EphB4 is a membrane-bound receptor tyrosine kinase (RTK) commonly over-produced by many epithelial cancers but with low to no expression in most normal adult…”
Get full text

EphB4 localises to the nucleus of prostate cancer cells by Mertens-Walker, Inga, Lisle, Jessica E., Nyberg, William A., Stephens, Carson R., Burke, Leslie, Rutkowski, Raphael, Herington, Adrian C., Stephenson, Sally-Anne

“…The EphB4 receptor tyrosine kinase is over-expressed in a variety of different epithelial cancers including prostate where it has been shown to be involved in…”
Get full text