Search Results - "Liskamp, Rob M. J."

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  1. 1

    Synthesis and Applications of Biomedical and Pharmaceutical Polymers via Click Chemistry Methodologies by van Dijk, Maarten, Rijkers, Dirk T. S, Liskamp, Rob M. J, van Nostrum, Cornelus F, Hennink, Wim E

    Published in Bioconjugate chemistry (18-11-2009)
    “…In this review, the synthesis and application of biomedical and pharmaceutical polymers synthesized via the copper(I)-catalyzed alkyne-azide cycloaddition, the…”
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  2. 2

    Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis by Morrison, Stephen D, Liskamp, Rob M. J, Prunet, Joëlle

    Published in Organic letters (20-04-2018)
    “…Olefin cross metathesis is reported for the first time to attach small molecules to a range of novel polyethers with a poly­(ethylene glycol) backbone and…”
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  3. 3

    Synthesis and Characterization of Enzymatically Biodegradable PEG and Peptide-Based Hydrogels Prepared by Click Chemistry by van Dijk, Maarten, van Nostrum, Cornelus F, Hennink, Wim E, Rijkers, Dirk T. S, Liskamp, Rob M. J

    Published in Biomacromolecules (14-06-2010)
    “…Herein we describe the synthesis and rheological characterization of a series of enzymatically sensitive PEG and peptide-based hydrogels by the Cu(I)-catalyzed…”
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  4. 4

    Broad-Spectrum Antimalarial Activity of Peptido Sulfonyl Fluorides, a New Class of Proteasome Inhibitors by TSCHAN, Serena, BROUWER, Arwin J, MORDMÜLLER, Benjamin, WERKHOVEN, Paul R, JONKER, Anika M, WAGNER, Lena, KNITTEL, Sarah, AMINAKE, Makoah Nigel, PRADEL, Gabriele, JOANNY, Fanny, LISKAMP, Rob M. J

    Published in Antimicrobial Agents and Chemotherapy (01-08-2013)
    “…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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  5. 5

    Polar Hinges as Functionalized Conformational Constraints in (Bi)cyclic Peptides by van de Langemheen, Helmus, Korotkovs, Valerijs, Bijl, Joachim, Wilson, Claire, Kale, Sangram S., Heinis, Christian, Liskamp, Rob M. J.

    “…Two polar hinges for cyclization of peptides have been developed, leading to bicyclic peptides and cyclized peptides with improved solubility and biological…”
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  6. 6

    The Vancomycin−Nisin(1−12) Hybrid Restores Activity against Vancomycin Resistant Enterococci by Arnusch, Christopher J, Bonvin, Alexandre M. J. J, Verel, Anne Marie, Jansen, Wouter T. M, Liskamp, Rob M. J, de Kruijff, Ben, Pieters, Roland J, Breukink, Eefjan

    Published in Biochemistry (Easton) (02-12-2008)
    “…Lipid II is a crucial component in bacterial cell wall synthesis [Breukink, E., et al. (1999) Science 286, 2361−2364]. It is the target of a number of…”
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  7. 7

    Enhanced Membrane Pore Formation by Multimeric/Oligomeric Antimicrobial Peptides by Arnusch, Christopher J, Branderhorst, Hilbert, de Kruijff, Ben, Liskamp, Rob M. J, Breukink, Eefjan, Pieters, Roland J

    Published in Biochemistry (Easton) (20-11-2007)
    “…The pore-forming antibacterial peptide magainin 2 was made divalent, tetravalent, and octavalent via a copper(I)-mediated 1−3 dipolar cycloaddition reaction…”
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  8. 8

    Potent and Highly Selective Inhibitors of the Proteasome Trypsin-like Site by Incorporation of Basic Side Chain Containing Amino Acid Derived Sulfonyl Fluorides by Artschwager, Raik, Ward, David J, Gannon, Susan, Brouwer, Arwin J, van de Langemheen, Helmus, Kowalski, Hubert, Liskamp, Rob M. J

    Published in Journal of medicinal chemistry (28-06-2018)
    “…A unique category of basic side chain containing amino acid derived sulfonyl fluorides (SFs) has been synthesized for incorporation into new proteasome…”
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  9. 9

    Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics by Guardiola, Salvador, Prades, Roger, Mendieta, Laura, Brouwer, Arwin J, Streefkerk, Jelle, Nevola, Laura, Tarragó, Teresa, Liskamp, Rob M J, Giralt, Ernest

    Published in Cell chemical biology (16-08-2018)
    “…Prolyl oligopeptidase (POP), a serine protease highly expressed in the brain, has recently emerged as an enticing therapeutic target for the treatment of…”
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  10. 10

    Synthesis and biological evaluation of novel irreversible serine protease inhibitors using amino acid based sulfonyl fluorides as an electrophilic trap by Brouwer, Arwin J., Ceylan, Tarik, Jonker, Anika M., Linden, Tima van der, Liskamp, Rob M.J.

    Published in Bioorganic & medicinal chemistry (01-04-2011)
    “…We have designed and synthesized novel irreversible serine protease inhibitors containing aliphatic sulfonyl fluorides as an electrophilic trap. These…”
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  11. 11

    Synthesis, Antimicrobial Activity, and Membrane Permeabilizing Properties of C‑Terminally Modified Nisin Conjugates Accessed by CuAAC by Slootweg, Jack C, van der Wal, Steffen, Quarles van Ufford, H. C, Breukink, Eefjan, Liskamp, Rob M. J, Rijkers, Dirk T. S

    Published in Bioconjugate chemistry (18-12-2013)
    “…Functionalization of the lantibiotic nisin with fluorescent reporter molecules is highly important for the understanding of its mode of action as a potent…”
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    New properties of wheat bran: anti‐biofilm activity and interference with bacteria quorum‐sensing systems by González‐Ortiz, Gemma, Quarles Van Ufford, H. C, Halkes, S. Bart A, Cerd ‐Cuéllar, Marta, Beukelman, Cees J, Pieters, Roland J, Liskamp, Rob M. J, Pérez, José F, Martín‐Orue, Susana M

    Published in Environmental microbiology (01-05-2014)
    “…Some plant extracts, have been demonstrated to interfere with the microbial metabolism of several pathogenic bacteria. Within this antimicrobial properties it…”
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  14. 14

    TMTHSI, a superior 7-membered ring alkyne containing reagent for strain-promoted azide-alkyne cycloaddition reactions by Weterings, Jimmy, Rijcken, Cristianne J. F, Veldhuis, Harald, Meulemans, Tommi, Hadavi, Darya, Timmers, Matt, Honing, Maarten, Ippel, Hans, Liskamp, Rob M. J

    Published in Chemical science (Cambridge) (10-08-2020)
    “…We describe the development of TMTH- S ulfox I mine (TMTH SI ) as a superior click reagent. This reagent combines a great reactivity, with small size and low…”
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    Resin-Bound Sulfonyl Azides:  Efficient Loading and Activation Strategy for the Preparation of the N-Acyl Sulfonamide Linker by Merkx, Remco, van Haren, Matthijs J, Rijkers, Dirk T. S, Liskamp, Rob M. J

    Published in Journal of organic chemistry (08-06-2007)
    “…This paper describes an optimized protocol for the efficient loading of resin-bound aminoethane sulfonyl azides by either Boc- or Fmoc-protected amino…”
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  17. 17

    Peptides and Proteins as a Continuing Exciting Source of Inspiration for Peptidomimetics by Liskamp, Rob M. J., Rijkers, Dirk T. S., Kruijtzer, John A. W., Kemmink, Johan

    “…Despite their enormous diversity in biological function and structure, peptides and proteins are endowed with properties that have induced and stimulated the…”
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  18. 18

    Inhibition of Streptococcus suis Adhesion by Dendritic Galabiose Compounds at Low Nanomolar Concentration by JOOSTEN, John A. F., LOIMARANTA, Vuokko, APPELDOORN, Chantal C. M., HAATAJA, Sauli, EL MAATE, Fatna Ait, LISKAMP, Rob M. J., FINNE, Jukka, PIETERS, Roland J.

    Published in Journal of medicinal chemistry (16-12-2004)
    “…A series of mono-, di-, and tetravalent galabiose (Galalpha1-4Gal) compounds were synthesized in good yields by coupling of a general carboxylic acid-bearing…”
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  19. 19

    Molecular Construction of Sulfonamide Antisense Oligonucleotides by Korotkovs, Valerijs, Reichenbach, Linus F, Pescheteau, Clémentine, Burley, Glenn A, Liskamp, Rob M. J

    Published in Journal of organic chemistry (06-09-2019)
    “…An efficient and scalable synthesis of new oligonucleotide monomers was developed for replacement of the phosphodiester backbone of RNA by a…”
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  20. 20

    Characterization and Activity of an Immobilized Antimicrobial Peptide Containing Bactericidal PEG-Hydrogel by Cleophas, Rik T. C, Sjollema, Jelmer, Busscher, Henk J, Kruijtzer, John A. W, Liskamp, Rob M. J

    Published in Biomacromolecules (08-09-2014)
    “…A single step immobilization-polymerization strategy of a highly active antimicrobial peptide into a soft hydrogel network on a poly(ethylene terephthalate)…”
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