Search Results - "Liskamp, R M J"

Highly tunable thiosulfonates as a novel class of cysteine protease inhibitors with anti-parasitic activity against Schistosoma mansoni by Ward, D.J., Van de Langemheen, H., Koehne, E., Kreidenweiss, A., Liskamp, R.M.J.

“…[Display omitted] The development of a new class of cysteine protease inhibitors utilising the thiosulfonate moiety as an SH specific electrophile is…”
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Molecular construction of HIV-gp120 discontinuous epitope mimics by assembly of cyclic peptides on an orthogonal alkyne functionalized TAC-scaffold by Werkhoven, P R, Elwakiel, M, Meuleman, T J, Quarles van Ufford, H C, Kruijtzer, J A W, Liskamp, R M J

“…Mimics of discontinuous epitopes of for example bacterial or viral proteins may have considerable potential for the development of synthetic vaccines,…”
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Scaffolded multiple cyclic peptide libraries for protein mimics by native chemical ligation by van de Langemheen, H, van Hoeke, M, Quarles van Ufford, H C, Kruijtzer, J A W, Liskamp, R M J

“…The accessibility to collections, libraries and arrays of cyclic peptides is increasingly important since cyclic peptides may provide better mimics of the…”
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A Versatile Method for the Conjugation of Proteins and Peptides to Poly[2-(dimethylamino)ethyl methacrylate] by van Dijk-Wolthuis, W. N. E, van de Wetering, P, Hinrichs, W. L. J, Hofmeyer, L. J. F, Liskamp, R. M. J, Crommelin, D. J. A, Hennink, W. E

“…Random copolymers of 2-(dimethylamino) ethyl methacrylate (DMAEMA) with aminoethyl methacrylate (AEMA) were synthesized by radical polymerization. The amount…”
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Thermodynamics of phosphotyrosine peptide-peptoid hybrids binding to the p56lck SH2 domain by Dekker, F. J., DE Mol, N. J., Liskamp, R. M. J.

“…A frequently used approach to transform peptides into more drug‐like compounds is preparation of the corresponding peptoids or peptide–peptoid hybrids…”
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Probing the Self-Assembly and the Accompanying Structural Changes of Hydrophobin SC3 on a Hydrophobic Surface by Mass Spectrometry by Wang, X., Permentier, H.P., Rink, R., Kruijtzer, J.A.W., Liskamp, R.M.J., Wösten, H.A.B., Poolman, B., Robillard, G.T.

“…The fungal class I hydrophobin SC3 self-assembles into an amphipathic membrane at hydrophilic-hydrophobic interfaces such as the water-air and water-Teflon…”
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Computer-Assisted Molecular Modeling of Tumor Promoters: Rationale for the Activity of Phorbol Esters, Teleocidin B, and Aplysiatoxin by Jeffrey, A. M., Liskamp, R. M. J.

“…In the two-stage model of skin carcinogenesis, it is believed that initiators bind to DNA and that tumor promoters such as phorbol 12-tetradecanoate 13-acetate…”
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Synthesis of a cyclic phosphopeptide containing a phosphodiester linkage by Van Oijen, A. H, Erkelens, C, Van Boom, J. H, Liskamp, R. M. J

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Thermodynamics of phosphotyrosine peptide–peptoid hybrids binding to the p56 lck SH2 domain by Dekker, F. J., DE Mol, N. J., Liskamp, R. M. J.

“…A frequently used approach to transform peptides into more drug‐like compounds is preparation of the corresponding peptoids or peptide–peptoid hybrids…”
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Synthesis and ring-opening reactions of functionalized sultines. New approach to sparsomycin by Liskamp, Rob M. J, Zeegers, Hubertus J, Ottenheijm, Harry C. J

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Conformational analysis of functionalized sultines by nuclear magnetic resonance and x-ray crystallography. Application of a generalized Karplus equation by Haasnoot, C. A. G, Liskamp, R. M. J, Van Dael, P. A. W, Noordik, J. H, Ottenheijm, H. C. J

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A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor by EICHHOLTZ, T, DE BONT, D. B. A, DE WIDT, J, LISKAMP, R. M. J, PLOEGH, H. L

“…Synthetic peptides corresponding to the pseudosubstrate domains of protein kinase C (PKC) have been used as specific inhibitors of PKC in in vitro assays and…”
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Increased stability of peptidesulfonamide peptidomimetics towards protease catalyzed degradation by de Bont, Dries B.A., Sliedregt-Bol, Karen M., Hofmeyer, Lovina J.F., Liskamp, Rob M.J.

“…Replacement of amide bonds in peptides by sulfonamide moieties resulted in peptidosulfonamides with an increased stability towards protease catalyzed…”
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Combinatorial chemistry of hydantoins: Combinatorial chemistry by BOEIJEN, A, KRUIJTZER, J. A. W, LISKAMP, R. M. J

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Comparing Mass Spectrometric Characteristics of Peptides and Peptoids by Heerma, W., Versluis, C., de Koster, C. G., Kruijtzer, J. A. W., Zigrovic, I., Liskamp, R. M. J.

“…The collision‐induced dissociation (CID) spectra of the [M+H]+ ions of a pentapeptide and the corresponding peptoid and retropeptoid have been compared. The…”
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Comparing Mass Spectrometric Characteristics of Peptides and Peptoids-2 by Heerma, Wigger, Boon, Jean-Paul J. L., Versluis, Cornelis, Kruijtzer, John A. W., Hofmeyer, Lovina J. F., Liskamp, Rob M. J.

“…The high‐energy collision‐induced dissociation (CID) spectra of the [M+H]+ and [M‐H]‐ ions of substance P fragment 6–11, the retropeptide and the corresponding…”
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Inhibition of neutrophil NADPH oxidase assembly by a myristoylated pseudosubstrate of protein kinase C by Verhoeven, A.J., Leusen, J.H., Kessels, G.C., Hilarius, P.M., de Bont, D.B., Liskamp, R.M.

“…To further define the role played by protein kinase C (PKC) in the activation of the neutrophil NADPH oxidase, we have utilized a pseudosubstrate of PKC which…”
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Solid-phase synthesis of O-phosphorothioylserine- and -threonine-containing peptides as well as of O-phosphoserine- and -threonine-containing peptides by De Bont, Dries B. A, Moree, Wilna J, Van Boom, Jacques H, Liskamp, Rob M. J

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Syntheses of Amino Acid Based Phosphodiester Linkage-Containing Cryptands as well as Diphosphorylated Macrocycles by van Oijen, Anita H, Huck, Nina P. M, Kruijtzer, John A. W, Erkelens, Cees, van Boom, Jacques H, Liskamp, Rob M. J

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Synthesis and structure of cyclic phosphopeptides containing a phosphodiester linkage by van Oijen, Anita H, Behrens, Stefan, Mierke, Dale F, Kessler, Horst, van Boom, Jacques H, Liskamp, Rob M. J

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