Search Results - "Liron, Tamar"

Mechanism and Prevention of Titanium Particle-Induced Inflammation and Osteolysis by Eger, Michal, Hiram-Bab, Sahar, Liron, Tamar, Sterer, Nir, Carmi, Yaron, Kohavi, David, Gabet, Yankel

“…The worldwide number of dental implants and orthopedic prostheses is steadily increasing. Orthopedic implant loosening, in the absence of infection, is mostly…”
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Enhancer methylation dynamics contribute to cancer plasticity and patient mortality by Bell, Rachel E, Golan, Tamar, Sheinboim, Danna, Malcov, Hagar, Amar, David, Salamon, Avi, Liron, Tamar, Gelfman, Sahar, Gabet, Yankel, Shamir, Ron, Levy, Carmit

“…During development, enhancers play pivotal roles in regulating gene expression programs; however, their involvement in cancer progression has not been fully…”
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The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Non-Melanoma Skin Cancer by Iden, Jennifer Ana, Raphael-Mizrahi, Bitya, Naim, Aaron, Kolomansky, Albert, Liron, Tamar, Neumann, Drorit, Vered, Marilena, Gabet, Yankel

“…Five million non-melanoma skin cancers occur globally each year, and it is one of the most common malignant cancers. The dysregulation of the endocannabinoid…”
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The Anti-Tumorigenic Role of Cannabinoid Receptor 2 in Colon Cancer: A Study in Mice and Humans by Iden, Jennifer Ana, Raphael-Mizrahi, Bitya, Awida, Zamzam, Naim, Aaron, Zyc, Dan, Liron, Tamar, Kasher, Melody, Livshits, Gregory, Vered, Marilena, Gabet, Yankel

“…The endocannabinoid system, particularly cannabinoid receptor 2 (CB2 in mice and CNR2 in humans), has controversial pathophysiological implications in colon…”
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Bone loss in C57BL/6J‐OlaHsd mice, a substrain of C57BL/6J carrying mutated alpha‐synuclein and multimerin‐1 genes by Liron, Tamar, Raphael, Bitya, Hiram‐Bab, Sahar, Bab, Itai A., Gabet, Yankel

“…The inbred mouse strain C57BL/6 is commonly used for the generation of transgenic mouse and is a well established strain in bone research. Different vendors…”
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The Non-Erythropoietic EPO Analogue Cibinetide Inhibits Osteoclastogenesis In Vitro and Increases Bone Mineral Density in Mice by Awida, Zamzam, Bachar, Almog, Saed, Hussam, Gorodov, Anton, Ben-Califa, Nathalie, Ibrahim, Maria, Kolomansky, Albert, Iden, Jennifer Ana, Graniewitz Visacovsky, Liad, Liron, Tamar, Hiram-Bab, Sahar, Brines, Michael, Gabet, Yankel, Neumann, Drorit

“…The two erythropoietin (EPO) receptor forms mediate different cellular responses to erythropoietin. While hematopoiesis is mediated via the homodimeric EPO…”
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Erythropoietin Mediated Bone Loss in Mice Is Dose-Dependent and Mostly Irreversible by Kolomansky, Albert, Hiram-Bab, Sahar, Ben-Califa, Nathalie, Liron, Tamar, Deshet-Unger, Naamit, Mittelman, Moshe, Oster, Howard S, Rauner, Martina, Wielockx, Ben, Neumann, Drorit, Gabet, Yankel

“…Recent studies have demonstrated that erythropoietin (EPO) treatment in mice results in trabecular bone loss. Here, we investigated the dose-response…”
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Erythropoietin Receptor (EPOR) Signaling in the Osteoclast Lineage Contributes to EPO-Induced Bone Loss in Mice by Awida, Zamzam, Hiram-Bab, Sahar, Bachar, Almog, Saed, Hussam, Zyc, Dan, Gorodov, Anton, Ben-Califa, Nathalie, Omari, Sewar, Omar, Jana, Younis, Liana, Iden, Jennifer Ana, Graniewitz Visacovsky, Liad, Gluzman, Ida, Liron, Tamar, Raphael-Mizrahi, Bitya, Kolomansky, Albert, Rauner, Martina, Wielockx, Ben, Gabet, Yankel, Neumann, Drorit

“…Erythropoietin (EPO) is a pleiotropic cytokine that classically drives erythropoiesis but can also induce bone loss by decreasing bone formation and increasing…”
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Therapeutic Potential of Vasoactive Intestinal Peptide and its Derivative Stearyl-Norleucine-VIP in Inflammation-Induced Osteolysis by Eger, Michal, Liron, Tamar, Hiram-Bab, Sahar, Awida, Zamzam, Giladi, Eliezer, Dangoor, David, Fridkin, Mati, Kohavi, David, Gozes, Illana, Gabet, Yankel

“…The common use of dental and orthopedic implants calls for special attention to the immune response leading to peri-prosthetic bone loss and implant failure…”
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Anti-CD20-Mediated B Cell Depletion Is Associated With Bone Preservation in Lymphoma Patients and Bone Mass Increase in Mice by Kolomansky, Albert, Kaye, Irit, Ben-Califa, Nathalie, Gorodov, Anton, Awida, Zamzam, Sadovnic, Ofer, Ibrahim, Maria, Liron, Tamar, Hiram-Bab, Sahar, Oster, Howard S, Sarid, Nadav, Perry, Chava, Gabet, Yankel, Mittelman, Moshe, Neumann, Drorit

“…Immunotherapy with anti-CD20-specific antibodies (rituximab), has become the standard of care for B cell lymphoproliferative disorders and many autoimmune…”
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The non-erythropoietic analogue cibinetide inhibits osteoclastogenesis in vitro and increases bone density in mice by Awida, Zamzam, Kolomansky, Albert, Hiram-Bab, Sahar, Ben-Califa, Nathalie, Saad, Hussam, Liron, Tamar, Ibrahim, Maria, Brines, Michael, Gabet, Yankel, Neumann, Drorit

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Scaling of titanium implants entrains inflammation-induced osteolysis by Eger, Michal, Sterer, Nir, Liron, Tamar, Kohavi, David, Gabet, Yankel

“…With millions of new dental and orthopedic implants inserted annually, periprosthetic osteolysis becomes a major concern. In dentistry, peri-implantitis…”
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Isozyme-Specific Abnormalities of PKC in Thyroid Cancer: Evidence for Post-Transcriptional Changes in PKC Epsilon by Knauf, Jeffrey A., Ward, Laura S., Nikiforov, Yuri E., Nikiforova, Marina, Puxeddu, Efisio, Medvedovic, Mario, Liron, Tamar, Mochly-Rosen, Daria, Fagin, James A.

“…PKC isozymes are the major binding proteins for tumor-promoting phorbol esters, and PKC activity is abnormal in a number of different human cancers. Less is…”
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Erythropoietin directly stimulates osteoclast precursors and induces bone loss by Hiram‐Bab, Sahar, Liron, Tamar, Deshet‐Unger, Naamit, Mittelman, Moshe, Gassmann, Max, Rauner, Martina, Franke, Kristin, Wielockx, Ben, Neumann, Drorit, Gabet, Yankel

“…ABSTRACT Erythropoietin (EPO) primarily regulates red blood cell formation, and EPO serum levels are increased on hypoxic stress (e.g., anemia and altitude)…”
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Statins Enhance Rotator Cuff Healing by Stimulating the COX2/PGE2/EP4 Pathway: An In Vivo and In Vitro Study by Dolkart, Oleg, Liron, Tamar, Chechik, Ofir, Somjen, Dalia, Brosh, Tamar, Maman, Eran, Gabet, Yankel

“…Background: Statins are lipid-lowering drugs with many beneficial pleiotropic effects. Cyclooxygenase (COX2) selective inhibitors that are commonly prescribed…”
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Hormone‐Independent Sexual Dimorphism in the Regulation of Bone Resorption by Krox20 by Sabag, Elias, Halperin, Elinor, Liron, Tamar, Hiram‐Bab, Sahar, Frenkel, Baruch, Gabet, Yankel

“…ABSTRACT Krox20/EGR2 is a zinc finger transcription factor, implicated in the development of the hindbrain, nerve myelination, and tumor suppression. In…”
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The Non-Erythropoietic EPO Analogue (Cibinetide) Preserves Bone Mass in Mice by Awida, Zamzam, Bachar, Almog, Saed, Hussam, Gorodov, Anton, Ben-Califa, Nathalie, Ibrahim, Maria, Kolomansky, Albert, Iden, Jennifer Ana, Graniewitz Visacovsky, Liad, Liron, Tamar, Hiram-Bab, Sahar, Brines, Michael, Gabet, Yankel, Neumann, Drorit

“…Background and aims: Erythropoietin (EPO) is a pleiotropic cytokine, which besides its classical role in driving erythropoiesis, displays tissue protective and…”
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Anti-CD20-Mediated B Cell Depletion Is Associated with Reduced Osteoclastogenic Signals and Bone Mass Preservation: Clinical Observation in Patients with Follicular Lymphoma Supplemented By Animal Studies in a Murine Model by Kolomansky, Albert, Kay, Irit, Ben-Califa, Nathalie, Gorodov, Anton, Awida, Zamzam, Sadovnic, Ofer, Ibrahim, Maria, Liron, Tamar, Hiram-Bab, Sahar, Oster, Howard S., Sarid, Nadav, Perry, Chava, Gabet, Yankel, Mittelman, Moshe, Neumann, Drorit

“…Background and aims: Immunotherapy with anti-CD20-specific antibodies (e.g. rituximab), has become the standard of care for B cell lymphoproliferative…”
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Erythropoietin (EPO) Regulates Bone Mass Via EPO Receptors on Myeloid and Lymphocytic Cells by Hiram-Bab, Sahar, Kolomansky, Albert, Deshet-Unger, Naamit, Ben-Califa, Nathalie, Liron, Tamar, Rauner, Martina, Wielockx, Ben, Mittelman, Moshe, Oster, Howard S., Gabet, Yankel, Neumann, Drorit

“…Background and aims: Erythropoietin (EPO) is the key regulator of red blood cell production. In response to hypoxia, EPO levels can increase 1000-fold and…”
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Erythropoietin receptor in B cells plays a role in bone remodeling in mice by Deshet-Unger, Naamit, Kolomansky, Albert, Ben-Califa, Nathalie, Hiram-Bab, Sahar, Gilboa, Dafna, Liron, Tamar, Ibrahim, Maria, Awida, Zamzam, Gorodov, Anton, Oster, Howard S, Mittelman, Moshe, Rauner, Martina, Wielockx, Ben, Gabet, Yankel, Neumann, Drorit

“…Erythropoietin (EPO) is a key regulator of erythropoiesis. However, EPO receptors (EPO-Rs) are also expressed on non-erythroid cell types, including myeloid…”
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