Search Results - "Liput, Michal"
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Covering the Role of PGC-1α in the Nervous System
Published in Cells (Basel, Switzerland) (30-12-2021)“…The peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a well-known transcriptional coactivator involved in mitochondrial biogenesis…”
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Systems Genome: Coordinated Gene Activity Networks, Recurring Coordination Modules, and Genome Homeostasis in Developing Neurons
Published in International journal of molecular sciences (01-06-2024)“…As human progenitor cells differentiate into neurons, the activities of many genes change; these changes are maintained within a narrow range, referred to as…”
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A proof of concept ‘phase zero’ study of neurodevelopment using brain organoid models with Vis/near-infrared spectroscopy and electrophysiology
Published in Scientific reports (02-12-2020)“…Homeostatic control of neuronal excitability by modulation of synaptic inhibition (I) and excitation (E) of the principal neurons is important during brain…”
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Immune Factor, TNFα, Disrupts Human Brain Organoid Development Similar to Schizophrenia—Schizophrenia Increases Developmental Vulnerability to TNFα
Published in Frontiers in cellular neuroscience (28-08-2020)“…Schizophrenia (SZ) is a neurodevelopmental genetic disorder in which maternal immune activation (MIA) and increased Tumor Necrosis Factor-α (TNF) may…”
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Global Genome Conformational Programming during Neuronal Development Is Associated with CTCF and Nuclear FGFR1-The Genome Archipelago Model
Published in International journal of molecular sciences (31-12-2020)“…During the development of mouse embryonic stem cells (ESC) to neuronal committed cells (NCC), coordinated changes in the expression of 2851 genes take place,…”
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Safety of GMP-compliant iPSC lines generated by Sendai virus transduction is dependent upon clone identity and sex of the donor
Published in Folia neuropathologica (01-01-2024)“…Human induced pluripotent stem cells (hiPSCs) are a potential source of somatic cells for cell therapies due to their ability to self-renew and differentiate…”
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The Generation of Human iPSC Lines from Three Individuals with Dravet Syndrome and Characterization of Neural Differentiation Markers in iPSC-Derived Ventral Forebrain Organoid Model
Published in Cells (Basel, Switzerland) (16-01-2023)“…Dravet syndrome (DRVT) is a rare form of neurodevelopmental disorder with a high risk of sudden unexpected death in epilepsy (SUDEP), caused mainly (>80%…”
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The effect of polymorphism in the FADS2 gene on the fatty acid composition of bovine milk
Published in Archiv für Tierzucht (18-09-2019)“…Polyunsaturated fatty acids (PUFAs) play a role in a wide variety of physiological processes. They are produced by a series of desaturation and elongation…”
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Tools and approaches for analyzing the role of mitochondria in health, development and disease using human cerebral organoids
Published in Developmental neurobiology (Hoboken, N.J.) (01-07-2021)“…Mitochondria are cellular organelles involved in generating energy to power various processes in the cell. Although the pivotal role of mitochondria in…”
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Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid (LA, C18:2n-6) to α-Linolenic Acid (ALA, C18:3n-3) Ratio on the Mouse Liver Proteome
Published in Nutrients (15-05-2021)“…The aim of the study was to evaluate the effect of different types of high-fat diets (HFDs) on the proteomic profile of mouse liver. The analysis included four…”
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11
Safety of GMP-compliant iPSC lines generated by Sendai virus transduction is dependent upon clone identity and sex of the donor
Published in Folia neuropathologica (2024)“…Human induced pluripotent stem cells (hiPSCs) are a potential source of somatic cells for cell therapies due to their ability to self-renew and differentiate…”
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Journal Article -
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Model-based investigation of elasticity and spectral exponent from atomic force microscopy and electrophysiology in normal versus Schizophrenia human cerebral organoids
Published in 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC) (2022)“…The physiological origin of the aperiodic signal present in the electrophysiological recordings, called l/f neural noise, is unknown; nevertheless, it has been…”
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Conference Proceeding -
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Effects of Three-Month Administration of High-Saturated Fat Diet and High-Polyunsaturated Fat Diets with Different Linoleic Acid Ratio on the Mouse Liver Proteome
Published in Nutrients (01-05-2021)“…The aim of the study was to evaluate the effect of different types of high-fat diets (HFDs) on the proteomic profile of mouse liver. The analysis included four…”
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Journal Article -
14
The effect of polymorphism in the FADS2 gene on the fatty acid composition of bovine milk
Published in Archiv für Tierzucht (18-09-2019)“…Polyunsaturated fatty acids (PUFAs) play a role in a wide variety of physiological processes. They are produced by a series of desaturation and elongation…”
Get full text
Journal Article