Search Results - "Lipscomb, Michael"

sCD163 levels as a biomarker of disease severity in leprosy and visceral leishmaniasis by Silva, Ricardo Luís Louzada, Santos, Marcio B, Almeida, Priscila L S, Barros, Thayse S, Magalhães, Lucas, Cazzaniga, Rodrigo A, Souza, Patrícia R M, Luz, Nívea F, França-Costa, Jaqueline, Borges, Valeria M, Lima-Junior, Djalma S, Lipscomb, Michael W, Duthie, Malcolm S, Reed, Steven G, Almeida, Roque Pacheco, Jesus, Amélia Ribeiro

“…CD163, receptor for the haptoglobin-hemoglobin complex, is expressed on monocytes/macrophages and neutrophils. A soluble form of CD163 (sCD163) has been…”
Get full text

CD40-CD40L cross-talk drives fascin expression in dendritic cells for efficient antigen presentation to CD4+ T cells by Elizondo, Diana M, Andargie, Temesgen E, Kubhar, Dineeta S, Gugssa, Ayele, Lipscomb, Michael W

“…Fascin is an actin-bundling protein that, among immune cells, is restricted to expression in dendritic cells (DCs). Previous reports have suggested that fascin…”
Get full text

Space-time risk cluster of visceral leishmaniasis in Brazilian endemic region with high social vulnerability: An ecological time series study by Ribeiro, Caique J N, Dos Santos, Allan D, Lima, Shirley V M A, da Silva, Eliete R, Ribeiro, Bianca V S, Duque, Andrezza M, Peixoto, Marcus V S, Dos Santos, Priscila L, de Oliveira, Iris M, Lipscomb, Michael W, de Araújo, Karina C G M, de Moura, Tatiana R

“…Despite visceral leishmaniasis (VL) being epidemic in most Brazilian regions, the Northeast region is responsible for the highest morbidity and mortality…”
Get full text

IL‐10 producing CD8+ CD122+ PD‐1+ regulatory T cells are expanded by dendritic cells silenced for Allograft Inflammatory Factor‐1 by Elizondo, Diana M., Andargie, Temesgen E., Haddock, Naomi L., da Silva, Ricardo L. Louzada, Moura, Tatiana Rodrigues, Lipscomb, Michael W.

“…Allograft Inflammatory Factor‐1 (AIF1) is a cytoplasmic scaffold protein that contains Ca2+ binding EF‐hand and PDZ interaction domains important for mediating…”
Get full text

Inhibition of Allograft Inflammatory Factor-1 in Dendritic Cells Restrains CD4 + T Cell Effector Responses and Induces CD25 + Foxp3 + T Regulatory Subsets by Elizondo, Diana M, Andargie, Temesgen E, Yang, Dazhi, Kacsinta, Apollo D, Lipscomb, Michael W

“…Allograft inflammatory factor-1 (AIF1) is a cytoplasmic scaffold protein shown to influence immune responses in macrophages and microglial cells. The protein…”
Get full text

Fascin1 promotes cell migration of mature dendritic cells by Yamakita, Yoshihiko, Matsumura, Fumio, Lipscomb, Michael W, Chou, Po-chien, Werlen, Guy, Burkhardt, Janis K, Yamashiro, Shigeko

“…Dendritic cells (DCs) play central roles in innate and adaptive immunity. Upon maturation, DCs assemble numerous veil-like membrane protrusions, disassemble…”
Get full text

Drebrin 1 in dendritic cells regulates phagocytosis and cell surface receptor expression through recycling for efficient antigen presentation by Elizondo, Diana M., Andargie, Temesgen E., Haddock, Naomi L., Boddie, Thomas A., Lipscomb, Michael W.

“…Summary Phagocytosis, macropinocytosis and antigen presentation by dendritic cells (DC) requires reorganization of the actin cytoskeleton. Drebrin (Dbn1) is an…”
Get full text

Value-based modeling for mobile health application development by Lipscomb, Michael M, Mohammad, Alhefdi, Abdulrahman, Alharthi, Jololian, Leon

“…In this paper is presented the use of value-based modeling, traditionally a business development tool, for the improvement of mobile health app design. The…”
Get full text

Leishmania donovani infection suppresses Allograft Inflammatory Factor-1 in monocytes and macrophages to inhibit inflammatory responses by da Silva, Ricardo Louzada, Elizondo, Diana M., Brandy, Nailah Z. D., Haddock, Naomi L., Boddie, Thomas A., de Oliveira, Laís Lima, de Jesus, Amélia Ribeiro, de Almeida, Roque Pacheco, de Moura, Tatiana Rodrigues, Lipscomb, Michael W.

“…Macrophages and monocytes are important for clearance of Leishmania infections. However, immune evasion tactics employed by the parasite results in suppressed…”
Get full text

Pancreatic islets seeded in a novel bioscaffold forms an organoid to rescue insulin production and reverse hyperglycemia in models of type 1 diabetes by Elizondo, Diana M., Brandy, Nailah Z. D., da Silva, Ricardo L. L., de Moura, Tatiana R., Ali, Jamel, Yang, Dazhi, Lipscomb, Michael W.

“…Therapeutic approaches to combat type 1 diabetes (T1D) include donor pancreas transplantation, exogenous insulin administration and immunosuppressive…”
Get full text

Allograft Inflammatory Factor-1 Governs Hematopoietic Stem Cell Differentiation Into cDC1 and Monocyte-Derived Dendritic Cells Through IRF8 and RelB in vitro by Elizondo, Diana M, Brandy, Nailah Z D, da Silva, Ricardo L L, Haddock, Naomi L, Kacsinta, Apollo D, de Moura, Tatiana R, Lipscomb, Michael W

“…The multistep differentiation process from hematopoietic stem cells through common myeloid progenitors into committed dendritic cell (DC) subsets remains to be…”
Get full text

Influence of testosterone in neglected tropical diseases: Clinical aspects in leprosy and in vitro experiments in Leishmaniasis by de Oliveira Rekowsky, Laís Lima, de Oliveira, Daniela Teles, Cazzaniga, Rodrigo Anselmo, Magalhães, Lucas Sousa, Albuquerque, Lenise Franco, Araujo, Jonnia Maria Sherlock, Tenório, Martha Débora Lira, Machado, Tiziane Cotta, Lipscomb, Michael W., dos Santos, Priscila Lima, Ribeiro de Jesus, Amelia, Bezerra-Santos, Márcio, da Silva, Ricardo Luís Louzada

“…Neglected tropical diseases encompass a group of chronic and debilitating infectious diseases that primarily affect marginalized populations. Among these…”
Get full text

Increased thiol levels in antimony-resistant Leishmania infantum isolated from treatment-refractory visceral leishmaniasis in Brazil by Magalhães, Lucas S, Bomfim, Lays Gs, Mota, Sthefanne G, Cruz, Geydson S, Corrêa, Cristiane B, Tanajura, Diego M, Lipscomb, Michael W, Borges, Valéria M, Jesus, Amélia R de, Almeida, Roque P de, Moura, Tatiana R de

“…BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance…”
Get full text

Leishmania infantum Induces the Release of sTREM-1 in Visceral Leishmaniasis by Bomfim, Lays G S, Magalhães, Lucas S, Santos-Filho, Marcello A A, Peres, Nalu T A, Corrêa, Cristiane B, Tanajura, Diego M, Silva, Angela M, Lipscomb, Michael W, Borges, Valéria M, Jesus, Amélia R, Almeida, Roque P, de Moura, Tatiana R

“…Visceral leishmaniasis (VL) is a systemic transmissible disease that remains to be a major global health problem. The inflammatory response during VL is…”
Get full text

sTREM-1 and TNF-α levels are associated with the clinical outcome of leprosy patients by Bezerra-Santos, Márcio, Bomfim, Lays G Santos, Santos, Camilla N Oliveira, Cunha, Maria Wiliane N, de Moraes, Eduardo J Rocha, Cazzaniga, Rodrigo A, Tenório, Martha D L, Araujo, Jonnia M Sherlock, Menezes-Silva, Lucas, Magalhães, Lucas Sousa, Barreto, Aline S, Reed, Steven G, Duthie, Malcolm S, Lipscomb, Michael W, de Almeida, Roque Pacheco, de Moura, Tatiana Rodrigues, de Jesus, Amélia Ribeiro

“…Leprosy reaction (LR) and physical disability (PD) are the most significant clinical complications of leprosy. Herein, we assessed the circulating…”
Get full text

Solving Knights Covering Problem by a Hybrid Algorithm by Guldal, Serkan, Tanik, Murat M., Lipscomb, Michael Mcfall

“…There are problems which do not have analytical solutions and require algorithms (such as Backtracking) that use brute force. The time complexity of these…”
Get full text

Allograft inflammatory factor-1 in myeloid cells drives autoimmunity in type 1 diabetes by Elizondo, Diana M, Brandy, Nailah Zd, da Silva, Ricardo L, de Moura, Tatiana R, Lipscomb, Michael W

“…Allograft inflammatory factor-1 (AIF1) is a calcium-responsive cytoplasmic scaffold protein that directs hematopoiesis and immune responses within dendritic…”
Get full text

Epidemiological aspects and spatial distribution of human and canine visceral leishmaniasis in an endemic area in northeastern Brazil by Campos, Roseane, Santos, Márcio, Tunon, Gabriel, Cunha, Luana, Magalhães, Lucas, Moraes, Juliana, Ramalho, Danielle, Lima, Sanmy, Pacheco, José Antônio, Lipscomb, Michael, Ribeiro de Jesus, Amélia, Pacheco de Almeida, Roque

“…Visceral leishmaniasis (VL) is a systemic disease endemic in tropical countries and transmitted through sand flies. In particular, Canis familiaris (or…”
Get full text

Dispositional depression and hostility are associated with inflammatory markers of cardiovascular disease in African Americans by Mwendwa, Denee T, Ali, Mana K, Sims, Regina C, Cole, Angela P, Lipscomb, Michael W, Levy, Shellie-Anne, Callender, Clive O, Campbell, Alfonso L

“…Highlight ► Our findings highlight the importance of examining dispositional characteristics when assessing cardiovascular disease risk in African Americans…”
Get full text

DC expressing transgene Foxp3 are regulatory APC by Lipscomb, Michael W, Taylor, Jennifer L, Goldbach, Cristina J, Watkins, Simon C, Wesa, Amy K, Storkus, Walter J

“…Tolerogenic DC and suppressive Foxp3⁺ Treg play important roles in preventing autoimmunity and allograft rejection. We report that (adenovirus mediated)…”
Get full text