Search Results - "Lipkow, Karen"

Changing cellular location of CheZ predicted by molecular simulations by Lipkow, Karen

“…In the chemotaxis pathway of the bacterium Escherichia coli, signals are carried from a cluster of receptors to the flagellar motors by the diffusion of the…”
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An integrated model of transcription factor diffusion shows the importance of intersegmental transfer and quaternary protein structure for target site finding by Schmidt, Hugo G, Sewitz, Sven, Andrews, Steven S, Lipkow, Karen

“…We present a computational model of transcription factor motion that explains both the observed rapid target finding of transcription factors, and how this…”
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The Chemotactic Behavior of Computer-Based Surrogate Bacteria by Bray, Dennis, Levin, Matthew D., Lipkow, Karen

“…Chemotaxis is the process by which organisms migrate toward nutrients and favorable environments and away from toxins and unfavorable environments. In many…”
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Simulated Diffusion of Phosphorylated CheY through the Cytoplasm of Escherichia coli by Lipkow, Karen, Andrews, Steven S, Bray, Dennis

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The autoregulation of a eukaryotic DNA transposon by Claeys Bouuaert, Corentin, Lipkow, Karen, Andrews, Steven S, Liu, Danxu, Chalmers, Ronald

“…How do DNA transposons live in harmony with their hosts? Bacteria provide the only documented mechanisms for autoregulation, but these are incompatible with…”
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Amelioration of protein misfolding disease by rapamycin: Translation or autophagy? by Wyttenbach, Andreas, Hands, Sarah, King, Matthew A., Lipkow, Karen, Tolkovsky, Aviva M.

“…Rapamycin is an inhibitor of mTOR, a key component of the mTORC1 complex that controls the growth and survival of cells in response to growth factors,…”
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Early Intermediates of mariner Transposition: Catalysis without Synapsis of the Transposon Ends Suggests a Novel Architecture of the Synaptic Complex by Lipkow, Karen, Buisine, Nicolas, Lampe, David J., Chalmers, Ronald

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Promiscuous Target Interactions in the mariner Transposon Himar1 by Lipkow, Karen, Buisine, Nicolas, Chalmers, Ronald

“…We have previously characterized the early intermediates of mariner transposition. Here we characterize the target interactions that occur later in the…”
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Complete Nucleotide Sequence of Tn10 by Chalmers, R, Sewitz, S, Lipkow, K, Crellin, P

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Systems Biology Approaches for Understanding Genome Architecture by Sewitz, Sven, Lipkow, Karen

“…The linear and three-dimensional arrangement and composition of chromatin in eukaryotic genomes underlies the mechanisms directing gene regulation…”
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Higher order assembly: folding the chromosome by Sewitz, Sven A, Fahmi, Zahra, Lipkow, Karen

“…[Display omitted] •An overview of the general features of genome organisation.•Recent advances in determining promoter-enhancer interactions genome wide.•Brief…”
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Changing Cellular Location of CheZ Predicted by Molecular Simulations by Lipkow, Karen

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Model for Protein Concentration Gradients in the Cytoplasm by Lipkow, Karen, Odde, David J.

“…Intracellular protein concentration gradients are generally thought to be unsustainable at steady-state due to diffusion. Here we show how protein…”
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Rapid turnover of stereocilia membrane proteins: evidence from the trafficking and mobility of plasma membrane Ca(2+)-ATPase 2 by Grati, M'hamed, Schneider, Mark E, Lipkow, Karen, Strehler, Emanuel E, Wenthold, Robert J, Kachar, Bechara

“…We studied the spatial distribution, mobility, and trafficking of plasma membrane Ca2+ATPase-2 (PMCA2), a protein enriched in the hair cell apical membrane and…”
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An Integrated Model of Transcription Factor Diffusion Shows the Importance of Intersegmental Transfer and Quaternary Protein Structure for Target Site Finding: e108575 by Schmidt, Hugo G, Sewitz, Sven, Andrews, Steven S, Lipkow, Karen

“…We present a computational model of transcription factor motion that explains both the observed rapid target finding of transcription factors, and how this…”
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Introducing simulated cellular architecture to the quantitative analysis of fluorescent microscopy by DePristo, Mark A., Chang, Lynne, Vale, Ronald D., Khan, Shahid M., Lipkow, Karen

“…Biological cells are complex and highly dynamic: many macromolecules are organized in loose assemblies, clusters or highly structured complexes, others exist…”
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Simulated diffusion of phosphorylated CheY through the cytoplasm of Escherichia coli. Commentary by LIPKOW, Karen, ANDREWS, Steven S, BRAY, Dennis, HAZELBAUER, Gerald L

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Rapid Turnover of Stereocilia Membrane Proteins: Evidence from the Trafficking and Mobility of Plasma Membrane Ca super(2+)-ATPase 2 by Grati, M'hamed, Schneider, Mark E, Lipkow, Karen, Strehler, Emanuel E, Wenthold, Robert J, Kachar, Bechara

“…We studied the spatial distribution, mobility, and trafficking of plasma membrane Ca super(2+)ATPase-2 (PMCA2), a protein enriched in the hair cell apical…”
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Rapid Turnover of Stereocilia Membrane Proteins: Evidence from the Trafficking and Mobility of Plasma Membrane Ca2+-ATPase 2 by Grati, M'hamed, Schneider, Mark E, Lipkow, Karen, Strehler, Emanuel E, Wenthold, Robert J, Kachar, Bechara

“…We studied the spatial distribution, mobility, and trafficking of plasma membrane Ca 2+ ATPase-2 (PMCA2), a protein enriched in the hair cell apical membrane…”
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Molecular analysis of hobo and himar 1 transposition by Lipkow, Karen

“…The aim of this study is to find out more about how eukaryotic transposons work. Transposons are widespread genetic elements that can autonomously change their…”
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