Search Results - "Lipke, Peter N."
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What We Do Not Know about Fungal Cell Adhesion Molecules
Published in Journal of fungi (Basel) (17-05-2018)“…There has been extensive research on structure and function of fungal cell adhesion molecules, but the most of the work has been about adhesins in and These…”
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Force-induced formation and propagation of adhesion nanodomains in living fungal cells
Published in Proceedings of the National Academy of Sciences - PNAS (30-11-2010)“…Understanding how cell adhesion proteins form adhesion domains is a key challenge in cell biology. Here, we use single-molecule atomic force microscopy (AFM)…”
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Cell-Cell Mating Interactions: Overview and Potential of Single-Cell Force Spectroscopy
Published in International journal of molecular sciences (20-01-2022)“…It is an understatement that mating and DNA transfer are key events for living organisms. Among the traits needed to facilitate mating, cell adhesion between…”
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Sticking to the Subject: Multifunctionality in Microbial Adhesins
Published in Journal of fungi (Basel) (29-03-2023)“…Bacterial and fungal adhesins mediate microbial aggregation, biofilm formation, and adhesion to host. We divide these proteins into two major classes:…”
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Through the back door: Unconventional protein secretion
Published in Cell surface (Amsterdam) (01-12-2020)“…Proteins are secreted from eukaryotic cells by several mechanisms besides the well-characterized classical secretory system. Proteins destined to enter the…”
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A Biochemical Guide to Yeast Adhesins: Glycoproteins for Social and Antisocial Occasions
Published in Microbiology and Molecular Biology Reviews (01-06-2007)“…Article Usage Stats Services MMBR Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Serum Amyloid P Component Binds Fungal Surface Amyloid and Decreases Human Macrophage Phagocytosis and Secretion of Inflammatory Cytokines
Published in mBio (12-03-2019)“…In patients with invasive fungal diseases, there is often little cellular inflammatory response. We tested the idea that binding of the human constitutive…”
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Glycomics for Microbes and Microbiologists
Published in mBio (09-08-2016)“…The recent article "Lectin-Glycan Interaction Network-Based Identification of Host Receptors of Microbial Pathogenic Adhesins" by Ielasi et al. describes a new…”
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Single-cell force spectroscopy of the medically important Staphylococcus epidermidis-Candida albicans interaction
Published in Nanoscale (21-11-2013)“…Despite the clinical importance of bacterial-fungal interactions, their molecular details are poorly understood. A hallmark of such medically important…”
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Structure and Conservation of Amyloid Spines From the Candida albicans Als5 Adhesin
Published in Frontiers in molecular biosciences (06-07-2022)“…Als family adhesins mediate adhesion to biological and abiotic substrates, as well as fungal cell aggregation, fungal-bacterial co-aggregation and biofilm…”
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The Paradoxical Effects of Serum Amyloid-P Component on Disseminated Candidiasis
Published in Pathogens (Basel) (06-11-2022)“…Serum amyloid P component (SAP) may play an important role in human fungal diseases. SAP binds to functional amyloid on the fungal surface and masks fungi from…”
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Strengthening relationships: amyloids create adhesion nanodomains in yeasts
Published in Trends in microbiology (Regular ed.) (01-02-2012)“…Budding yeasts adhere to biotic or abiotic surfaces and aggregate to form biofilms, using wall-anchored glycoprotein adhesins. The process is paradoxical:…”
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A role for amyloid in cell aggregation and biofilm formation
Published in PloS one (08-03-2011)“…Cell adhesion molecules in Saccharomyces cerevisiae and Candida albicans contain amyloid-forming sequences that are highly conserved. We have now used…”
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An Amyloid Core Sequence in the Major Candida albicans Adhesin Als1p Mediates Cell-Cell Adhesion
Published in mBio (08-10-2019)“…The human fungal commensal can become a serious opportunistic pathogen in immunocompromised hosts. The cell adhesion protein Als1p is a highly expressed member…”
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Garcinia xanthochymus Benzophenones Promote Hyphal Apoptosis and Potentiate Activity of Fluconazole against Candida albicans Biofilms
Published in Antimicrobial agents and chemotherapy (01-10-2015)“…Xanthochymol and garcinol, isoprenylated benzophenones purified from Garcinia xanthochymus fruits, showed multiple activities against Candida albicans…”
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Blocking Serum Amyloid-P Component from Binding to Macrophages and Augmenting Fungal Functional Amyloid Increases Macrophage Phagocytosis of Candida albicans
Published in Pathogens (Basel) (01-09-2022)“…Candida-macrophage interactions are important immune defense responses associated with disseminated and deep-seated candidiasis in humans. Cells of Candida…”
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Polymicrobial bloodstream infections involving Candida species: analysis of patients and review of the literature
Published in Diagnostic microbiology and infectious disease (01-12-2007)“…Abstract Candida species are the 4th most common cause of nosocomial bloodstream infections in North America. It is not widely appreciated, however, that many…”
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A New Function for Amyloid-Like Interactions: Cross-Beta Aggregates of Adhesins form Cell-to-Cell Bonds
Published in Pathogens (Basel) (11-08-2021)“…Amyloid structures assemble through a repeating type of bonding called “cross-β”, in which identical sequences in many protein molecules form β-sheets that…”
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Strain and temperature dependent aggregation of Candida auris is attenuated by inhibition of surface amyloid proteins
Published in Cell surface (Amsterdam) (15-12-2023)“…•The amyloid inhibitor Thioflavin-T inhibited C. auris aggregation.•Aggregating isolates do not exhibit any defects in cell separation.•Genomic differences…”
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Yeast Cell Adhesion Molecules Have Functional Amyloid-Forming Sequences
Published in Eukaryotic Cell (01-03-2010)“…Classifications Services EC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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