Search Results - "Lipinski, Jay"
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The evolving role of the lung microbiome in pulmonary fibrosis
Published in American journal of physiology. Lung cellular and molecular physiology (01-10-2020)“…Mucosal surfaces are constantly exposed to a microbiome consisting of microorganisms that heavily influence human immunity and health. In the lung these…”
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Commensal Oral Microbiota, Disease Severity, and Mortality in Fibrotic Lung Disease
Published in American journal of respiratory and critical care medicine (01-05-2024)“…Oral microbiota associate with diseases of the mouth and serve as a source of lung microbiota. However, the role of oral microbiota in lung disease is unknown…”
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Toll-Interacting Protein and Altered Lung Microbiota in Idiopathic Pulmonary Fibrosis
Published in American journal of respiratory and critical care medicine (15-07-2022)Get full text
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Protein Arginine Methyltransferase 1 Interacts With PGC1α and Modulates Thermogenic Fat Activation
Published in Endocrinology (Philadelphia) (01-12-2019)“…Protein arginine methyltransferases (PRMTs) are enzymes that regulate the evolutionarily conserved process of arginine methylation. It has been reported that…”
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Epigenetic regulation of the PGE2 pathway modulates macrophage phenotype in normal and pathologic wound repair
Published in JCI insight (03-09-2020)“…Macrophages are a primary immune cell involved in inflammation, and their cell plasticity allows for transition from an inflammatory to a reparative phenotype…”
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Horizontal transmission of gut microbiota attenuates mortality in lung fibrosis
Published in JCI insight (28-11-2023)“…Pulmonary fibrosis is a chronic and often fatal disease. The pathogenesis is characterized by aberrant repair of lung parenchyma, resulting in loss of…”
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Epigenetic Regulation of TLR4 in Diabetic Macrophages Modulates Immunometabolism and Wound Repair
Published in The Journal of immunology (1950) (01-05-2020)“…Macrophages are critical for the initiation and resolution of the inflammatory phase of wound healing. In diabetes, macrophages display a prolonged…”
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Protein Arginine Methyltransferase 1 Interacts With PGC1[alpha] and Modulates Thermogenic Fat Activation
Published in Endocrinology (Philadelphia) (01-12-2019)“…Protein arginine methyltransferases (PRMTs) are enzymes that regulate the evolutionarily conserved process of arginine methylation. It has been reported that…”
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TNF-α regulates diabetic macrophage function through the histone acetyltransferase MOF
Published in JCI insight (12-03-2020)“…A critical component of wound healing is the transition from the inflammatory phase to the proliferation phase to initiate healing and remodeling of the wound…”
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