Search Results - "Lipińska, Andrea D."

The Role of IFITM Proteins in Tick-Borne Encephalitis Virus Infection by Chmielewska, Alicja M, Gómez-Herranz, Maria, Gach, Paulina, Nekulova, Marta, Bagnucka, Małgorzata A, Lipińska, Andrea D, Rychłowski, Michał, Hoffmann, Weronika, Król, Ewelina, Vojtesek, Borivoj, Sloan, Richard D, Bieńkowska-Szewczyk, Krystyna, Hupp, Ted, Ball, Kathryn

“…Tick-borne encephalitis virus (TBEV), of the genus , is a causative agent of severe encephalitis in regions of endemicity of northern Asia and central and…”
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IGF2 Peptide-Based LYTACs for Targeted Degradation of Extracellular and Transmembrane Proteins by Mikitiuk, Michał, Barczyński, Jan, Bielski, Przemysław, Arciniega, Marcelino, Tyrcha, Urszula, Hec, Aleksandra, Lipińska, Andrea D, Rychłowski, Michał, Holak, Tad A, Sitar, Tomasz

“…Lysosome-targeting chimeras (LYTACs) have recently been developed to facilitate the lysosomal degradation of specific extracellular and transmembrane molecular…”
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Long‐time scale simulations of virus‐like particles from three human‐norovirus strains by Lipska, Agnieszka G., Sieradzan, Adam K., Czaplewski, Cezary, Lipińska, Andrea D., Ocetkiewicz, Krzysztof M., Proficz, Jerzy, Czarnul, Paweł, Krawczyk, Henryk, Liwo, Adam

“…The dynamics of the virus like particles (VLPs) corresponding to the GII.4 Houston, GII.2 SMV, and GI.1 Norwalk strains of human noroviruses (HuNoV) that cause…”
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The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation by Wąchalska, Magda, Riepe, Celeste, Ślusarz, Magdalena J, Graul, Małgorzata, Borowski, Lukasz S, Qiao, Wenjie, Foltyńska, Michalina, Carette, Jan E, Bieńkowska-Szewczyk, Krystyna, Szczesny, Roman J, Kopito, Ron R, Lipińska, Andrea D

“…The transporter associated with antigen processing (TAP) is a key player in the major histocompatibility class I-restricted antigen presentation and an…”
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The N-terminal Proline Hinge Motif Controls the Structure of Bovine Herpesvirus 1-encoded Inhibitor of the Transporter Associated with Antigen Processing Required for its Immunomodulatory Function by Graul, Małgorzata, Karska, Natalia, Wąchalska, Magda, Krupa, Paweł, Ślusarz, Magdalena J., Lubocki, Marcin, Bieńkowska-Szewczyk, Krystyna, Rodziewicz-Motowidło, Sylwia, Sieradzan, Adam K., Lipińska, Andrea D.

“…[Display omitted] •UL49.5 of BoHV-1 inhibits TAP transporter by mechanisms undetermined on a molecular level.•Mutations in 52PPQ54 proline hinge resulted in…”
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Alphaherpesvirus gB Homologs Are Targeted to Extracellular Vesicles, but They Differentially Affect MHC Class II Molecules by Grabowska, Kinga, Wąchalska, Magda, Graul, Małgorzata, Rychłowski, Michał, Bieńkowska-Szewczyk, Krystyna, Lipińska, Andrea D

“…Herpesvirus envelope glycoprotein B (gB) is one of the best-documented extracellular vesicle (EVs)-incorporated viral proteins. Regarding the sequence and…”
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Structure determination of UL49.5 transmembrane protein from bovine herpesvirus 1 by NMR spectroscopy and molecular dynamics by Karska, Natalia, Graul, Małgorzata, Sikorska, Emilia, Zhukov, Igor, Ślusarz, Magdalena J., Kasprzykowski, Franciszek, Lipińska, Andrea D., Rodziewicz-Motowidło, Sylwia

“…The transporter associated with antigen processing (TAP) directly participates in the immune response as a key component of the cytosolic peptide to major…”
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Inhibition of apoptosis in BHV-1-infected cells depends on Us3 serine/threonine kinase and its enzymatic activity by Brzozowska, Agnieszka, Lipińska, Andrea D., Derewońko, Natalia, Lesiak, Dorota, Rychłowski, Michał, Rąbalski, Łukasz, Bieńkowska-Szewczyk, Krystyna

“…Us3 protein is a serine/threonine kinase conserved within the Alphaherpesvirinae subfamily of herpesviruses. The Us3 homologs of herpes simplex virus,…”
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Transmembrane regions of bovine herpesvirus 1-encoded UL49.5 and glycoprotein M regulate complex maturation and ER-Golgi trafficking by Graul, Małgorzata, Kisielnicka, Edyta, Rychłowski, Michał, Verweij, Marieke C, Tobler, Kurt, Ackermann, Mathias, Wiertz, Emmanuel J H J, Bieńkowska-Szewczyk, Krystyna, Lipińska, Andrea D

“…Bovine herpesvirus 1 (BoHV-1)-encoded UL49.5 (a homologue of herpesvirus glycoprotein N) can combine different functions, regulated by complex formation with…”
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Palmitoylated mNeonGreen Protein as a Tool for Visualization and Uptake Studies of Extracellular Vesicles by Wąchalska, Magda, Rychłowski, Michał, Grabowska, Kinga, Kowal, Kinga, Narajczyk, Magdalena, Bieńkowska-Szewczyk, Krystyna, Lipińska, Andrea D

“…Extracellular vesicles (EVs) are membranous nanoparticles released by cells as vital mediators of intercellular communication. As such, EVs have become an…”
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Investigation of the Effects of Primary Structure Modifications within the RRE Motif on the Conformation of Synthetic Bovine Herpesvirus 1‐Encoded UL49.5 Protein Fragments by Karska, Natalia, Graul, Małgorzata, Sikorska, Emilia, Ślusarz, Magdalena J., Zhukov, Igor, Kasprzykowski, Franciszek, Kubiś, Agnieszka, Lipińska, Andrea D., Rodziewicz‐Motowidło, Sylwia

“…Herpesviruses are the most prevalent viruses that infect the human and animal body. They can escape a host immune response in numerous ways. One way is to…”
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New baculovirus recombinants expressing Pseudorabies virus (PRV) glycoproteins protect mice against lethal challenge infection by Grabowska, Agnieszka K, Lipińska, Andrea D, Rohde, Jörg, Szewczyk, Boguslaw, Bienkowska-Szewczyk, Krystyna, Rziha, Hanns-Joachim

“…Abstract The present study demonstrates the protective potential of novel baculovirus recombinants, which express the glycoproteins gB, gC, or gD of…”
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The Capacity of UL49.5 Proteins To Inhibit TAP Is Widely Distributed among Members of the Genus Varicellovirus by VERWEIJ, Marieke C, LIPINSKA, Andrea D, WIERTZ, Emmanuel J. H. J, KOPPERS-LALIC, Danijela, VAN LEEUWEN, Wouter F, COHEN, Jeffrey I, KINCHINGTON, Paul R, MESSAOUDI, Ilhem, BIENKOWSKA-SZEWCZYK, Krystyna, RESSING, Maaike E, RIJSEWIJK, Frans A. M

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Structural and functional analysis of the TAP-inhibiting UL49.5 proteins of varicelloviruses by Verweij, Marieke C., Lipińska, Andrea D., Koppers-Lalic, Danijela, Quinten, Edwin, Funke, Jessica, van Leeuwen, Hans C., Bieńkowska-Szewczyk, Krystyna, Koch, Joachim, Ressing, Maaike E., Wiertz, Emmanuel J.H.J.

“…• The ER-luminal and TM domains of BoHV-1 UL49.5 are required for efficient interaction with TAP. • The ER-luminal and TM domains of BoHV-1 UL49.5 are required…”
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Fluorescent TAP as a Platform for Virus-Induced Degradation of the Antigenic Peptide Transporter by Wąchalska, Magda, Graul, Małgorzata, Praest, Patrique, Luteijn, Rutger D, Babnis, Aleksandra W, Wiertz, Emmanuel J H J, Bieńkowska-Szewczyk, Krystyna, Lipińska, Andrea D

“…Transporter associated with antigen processing (TAP), a key player in the major histocompatibility complex class I-restricted antigen presentation, makes an…”
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Bovine Herpesvirus 1 UL49.5 Protein Inhibits the Transporter Associated with Antigen Processing despite Complex Formation with Glycoprotein M by LIPINSKA, Andrea D, KOPPERS-LALIC, Danijela, RYCHLOWSKI, Michal, ADMIRAAL, Pieter, RIJSEWIJK, Frans A. M, BIENKOWSKA-SZEWCZYK, Krystyna, WIERTZ, Emmanuel J. H. J

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Why does the herpes simplex 1 virus-encoded UL49.5 protein fail to inhibit the TAP-dependent antigen presentation? by Karska, Natalia, Zhukov, Igor, Lipińska, Andrea D., Rodziewicz-Motowidło, Sylwia, Krupa, Paweł

“…Herpes simplex virus 1 (HSV-1) is a well-studied herpesvirus that causes various human diseases. Like other herpesviruses, HSV-1 produces the transmembrane…”
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Functional Analysis of a Frontal miRNA Cluster Located in the Large Latency Transcript of Pseudorabies Virus by Hoffmann, Weronika, Lipi?ska, Andrea D, Bie?kowska-Szewczyk, Krystyna

“…MicroRNAs (miRNAs) have been identified as a class of crucial regulators of virus-host crosstalk, modulating such processes as viral replication, antiviral…”
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Point mutations in BHV-1 Us3 gene abolish its ability to induce cytoskeletal changes in various cell types by Brzozowska, Agnieszka, Rychłowski, Michał, Lipińska, Andrea D., Bieńkowska-Szewczyk, Krystyna

“…The Us3 gene is conserved among alphaherpesviruses and codes for a protein kinase, a multifunctional protein involved in many phases of virus infection, like…”
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Varicellovirus UL49.5 proteins differentially affect the function of the transporter associated with antigen processing, TAP by Koppers-Lalic, D, Verweij, M.C, Lipinska, A.D, Wang, Y, Quinten, E, Reits, E.A, Koch, J, Loch, S, Rezende, M.M, Daus, F.J, Bienkowska-Szewczyk, K, Osterrieder, N, Mettenleiter, T.C, Heemskerk, M.H.M, Tampe, R, Neefjes, J.J, Chowdhury, S.I, Ressing, M.E, Rijsewijk, F.A.M, Wiertz, E.J.H.J

“…Cytotoxic T-lymphocytes play an important role in the protection against viral infections, which they detect through the recognition of virus-derived peptides,…”
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