Search Results - "Lipiäinen, Tiina"
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Direct comparison of low- and mid-frequency Raman spectroscopy for quantitative solid-state pharmaceutical analysis
Published in Journal of pharmaceutical and biomedical analysis (05-02-2018)“…[Display omitted] •Low- and mid-frequency Raman spectra were compared for quantitative analysis.•Ternary mixtures of piroxicam solid-state forms β, α2 and…”
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Low- versus Mid-frequency Raman Spectroscopy for in Situ Analysis of Crystallization in Slurries
Published in Molecular pharmaceutics (04-07-2022)“…Slurry studies are useful for exhaustive polymorph and solid-state stability screening of drug compounds. Raman spectroscopy is convenient for monitoring…”
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Comparison of melibiose and trehalose as stabilising excipients for spray-dried β-galactosidase formulations
Published in International journal of pharmaceutics (30-05-2018)“…[Display omitted] Spray-dried protein formulations commonly require stabilising excipients to prevent protein degradation during processing and storage, and…”
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Effect of trehalose and melibiose on crystallization of amorphous paracetamol
Published in International journal of pharmaceutics (30-11-2020)“…[Display omitted] This paper investigates the solid-state behavior of two-phase solid dispersions involving small molecules. The effect of two sugars,…”
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Spray-dried amorphous isomalt and melibiose, two potential protein-stabilizing excipients
Published in International journal of pharmaceutics (20-08-2016)“…[Display omitted] The possibility of producing amorphous isomalt and melibiose by spray drying was studied. The impact of process parameters on yield and…”
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Time-Gated Raman Spectroscopy for Quantitative Determination of Solid-State Forms of Fluorescent Pharmaceuticals
Published in Analytical chemistry (Washington) (03-04-2018)“…Raman spectroscopy is widely used for quantitative pharmaceutical analysis, but a common obstacle to its use is sample fluorescence masking the Raman signal…”
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Formulation and stability of cytokine therapeutics
Published in Journal of pharmaceutical sciences (01-02-2015)“…Cytokines are messenger proteins that regulate the proliferation and differentiation of cells and control immune responses. Interferons, interleukins, and…”
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Pectin and Mucin Enhance the Bioadhesion of Drug Loaded Nanofibrillated Cellulose Films
Published in Pharmaceutical research (01-07-2018)“…Purpose Bioadhesion is an important property of biological membranes, that can be utilized in pharmaceutical and biomedical applications. In this study, we…”
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Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions
Published in International journal of pharmaceutics (25-04-2018)“…[Display omitted] Solid dispersions (SDs) hold a proven potential in formulating poorly water-soluble drugs. The present paper investigates the interfacial…”
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