Search Results - "Lipari, Francesco"

Single-Well Monitoring of Protein−Protein Interaction and Phosphorylation−Dephosphorylation Events by Arcand, Mathieu, Roby, Philippe, Bossé, Roger, Lipari, Francesco, Padrós, Jaime, Beaudet, Lucille, Marcil, Alexandre, Dahan, Sophie

“…We combined oxygen channeling assays with two distinct chemiluminescent beads to detect simultaneously protein phosphorylation and interaction events that are…”
Get full text

Crystal structure of a class I α1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control by Vallée, François, Lipari, Francesco, Yip, Patrick, Sleno, Barry, Herscovics, Annette, Howell, P.Lynne

“…Mannose trimming is not only essential for N‐glycan maturation in mammalian cells but also triggers degradation of misfolded glycoproteins. The crystal…”
Get full text

Role of the Cysteine Residues in the α1,2-Mannosidase Involved in N-Glycan Biosynthesis in Saccharomyces cerevisiae by Lipari, Francesco, Herscovics, Annette

“…The Saccharomyces cerevisiae α1,2-mannosidase, which removes one specific mannose residue from Man9GlcNAc2 to form Man8GlcNAc2, is a member of a family of…”
Get full text

Soluble amyloid precursor protein α and β in CSF in Alzheimer's disease by Brinkmalm, Gunnar, Brinkmalm, Ann, Bourgeois, Philippe, Persson, Rita, Hansson, Oskar, Portelius, Erik, Mercken, Marc, Andreasson, Ulf, Parent, Stéphane, Lipari, Francesco, Öhrfelt, Annika, Bjerke, Maria, Minthon, Lennart, Zetterberg, Henrik, Blennow, Kaj, Nutu, Magdalena

“…Abstract Objective Cerebral accumulation of amyloid β (Aβ) is a pathological hallmark of Alzheimer’s disease (AD). Proteolytic processing of amyloid precursor…”
Get full text

Anti-drug Antibody Sample Testing and Reporting Harmonization by Jani, Darshana, Marsden, Robin, Gunsior, Michele, Hay, Laura Schild, Ward, Bethany, Cowan, Kyra J., Azadeh, Mitra, Barker, Breann, Cao, Liching, Closson, Kristin R., Coble, Kelly, Dholakiya, Sanjay L., Dusseault, Julie, Hays, Amanda, Herl, Carina, Hodsdon, Michael E., Irvin, Susan C., Kirshner, Susan, Kolaitis, Gerry, Kulagina, Nadia, Kumar, Seema, Lai, Ching Ha, Lipari, Francesco, Liu, Susana, Merdek, Keith D., Moldovan, Ioana R., Mozaffari, Reza, Pan, Luying, Place, Corina, Snoeck, Veerle, Manning, Marta Starcevic, Stocker, Dennis, Tary-Lehmann, Magdalena, Turner, Amy, Vainshtein, Inna, Verthelyi, Daniela, Williams, William T., Yan, Haoheng, Yan, Weili, Yang, Lili, Yang, Lin, Zemo, Jennifer, Zhong, Zhandong Don

“…A clear scientific and operational need exists for harmonized bioanalytical immunogenicity study reporting to facilitate communication of immunogenicity…”
Get full text

PS3-68 Low volume, highly sensitive immunoassays for detecting cytokines in animal fluids by Michaud, Jean-Francois, Rouleau, Nathalie, Brechler, Veronique, Lipari, Francesco

Get full text

Aβ1-15/16 as a Potential Diagnostic Marker in Neurodegenerative Diseases by Nutu, Magdalena, Bourgeois, Philippe, Zetterberg, Henrik, Portelius, Erik, Andreasson, Ulf, Parent, Stéphane, Lipari, Francesco, Hall, Sara, Constantinescu, Radu, Hansson, Oskar, Blennow, Kaj

“…Cerebrospinal fluid (CSF) biomarkers for Alzheimer’s disease (AD) reflect brain biochemistry. Using combined immunoprecipitation and mass spectrometry, we have…”
Get full text

The use of AlphaLISA in measurement of Aβ1-15/16 as a potential biomarker in neurodegenerative diseases by Nutu, Magdalena, Bourgeois, Philippe, Zetterberg, Henrik, Portelius, Erik, Lipari, Francesco, Parent, Stéphane, Hansson, Oskar, Blennow, Kaj

Get full text

P1‐022: The use of AlphaLISA in measurement of Aβ1–15/16 as a potential biomarker in neurodegenerative diseases by Nutu, Magdalena, Bourgeois, Philippe, Zetterberg, Henrik, Portelius, Erik, Lipari, Francesco, Parent, Stéphane, Hansson, Oskar, Blennow, Kaj

Get full text

A[beta]1-15/16 as a Potential Diagnostic Marker in Neurodegenerative Diseases by Nutu, Magdalena, Bourgeois, Philippe, Zetterberg, Henrik, Portelius, Erik, Andreasson, Ulf, Parent, Stéphane, Lipari, Francesco, Hall, Sara, Constantinescu, Radu, Hansson, Oskar, Blennow, Kaj

“…Cerebrospinal fluid (CSF) biomarkers for Alzheimerâ[euro](TM)s disease (AD) reflect brain biochemistry. Using combined immunoprecipitation and mass…”
Get full text

A beta 1-15/16 as a Potential Diagnostic Marker in Neurodegenerative Diseases by Nutu, Magdalena, Bourgeois, Philippe, Zetterberg, Henrik, Portelius, Erik, Andreasson, Ulf, Parent, Stephane, Lipari, Francesco, Hall, Sara, Constantinescu, Radu, Hansson, Oskar, Blennow, Kaj

“…Cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD) reflect brain biochemistry. Using combined immunoprecipitation and mass spectrometry, we have…”
Get full text

Calcium Binding to the Class I α-1,2-Mannosidase from Saccharomyces cerevisiae Occurs Outside the EF Hand Motif by Lipari, Francesco, Herscovics, Annette

“…Class I α-1,2-mannosidases are a family of Ca2+-dependent enzymes that have been conserved through eukaryotic evolution. These enzymes contain a conserved…”
Get full text

Purification and Biophysical Characterization of a Minimal Functional Domain and of an N-Terminal Zn2+-Binding Fragment from the Human Papillomavirus Type 16 E6 Protein by Lipari, Francesco, McGibbon, Graham A, Wardrop, Elizabeth, Cordingley, Michael G

“…The E6 Zn2+-binding protein of high-risk human papillomaviruses (HPVs) is one of the major transforming proteins encoded by these tumor viruses. A bacterial…”
Get full text

Role of the Cysteine Residues in the α1,2-Mannosidase Involved in N-Glycan Biosynthesis in Saccharomyces cerevisiae by Francesco Lipari, Annette Herscovics

“…The Saccharomyces cerevisiae α1,2-mannosidase, which removes one specific mannose residue from Man 9 GlcNAc 2 to form Man 8 GlcNAc 2 , is a member of a family…”
Get full text

Purification and Biophysical Characterization of a Minimal Functional Domain and of an N-Terminal Zn 2+ -Binding Fragment from the Human Papillomavirus Type 16 E6 Protein by Lipari, Francesco, McGibbon, Graham A., Wardrop, Elizabeth, Cordingley, Michael G.

Get full text

Crystal structure of a class I [alpha]1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality control by Vallee, Francois, Lipari, Francesco, Yip, Patrick, Sleno, Barry, Herscovics, Annette, P.Lynne Howell

“…Mannose trimming is not only essential for N-glycan maturation in mammalian cells but also triggers degradation of misfolded glycoproteins. The crystal…”
Get full text

The Saccharomyces cerevisiae Processing α1,2-Mannosidase Is an Inverting Glycosidase by Lipari, F., Goursalin, B.J., Herscovics, A.

“…The α1,2-mannosidase from Saccharomyces cerevisiae, which removes one specific α1,2-linked mannose residue from Man 9GlcNAc 2, is a member of the Class 1…”
Get full text

Structure and mechanism of action of the yeast class 1 α1,2-mannosidase involved in N-glycan biosynthesis by Lipari, Francesco

“…The Saccharomyces cerevisiae α1,2-mannosidase that removes one specific mannose residue from Man9GlcNAc 2 during the biosynthesis of N-glycans is a member of…”
Get full text

Crystallization and Preliminary X-Ray Analysis of the Class 1 α1,2-Mannosidase fromSaccharomyces cerevisiae by Dole, Kiran, Lipari, Francesco, Herscovics, Annette, Howell, P.Lynne

“…The α1,2-mannosidase fromSaccharomyces cerevisiaecatalyzes the conversion of Man9GlcNAc2to Man8GlcNAc2during the formation of N-linked oligosaccharides and is…”
Get full text

Glycosidase-catalyzed hydrolysis of 2-deoxyglucopyranosyl pyridinium salts: effect of the 2-OH group on binding and catalysis by Tanaka, Kelly SE, Zhu, Jiang, Huang, Xicai, Lipari, Francesco, Bennet, Andrew J

“…Three 2-deoxy-a-D-glucopyranosyl pyridinium tetrafluoroborates were tested for their binding affinity to a range of a-glucosidases and a- mannosidases. The…”
Get full text