Search Results - "Linu Jacob"

Epigenetic therapy of cancer with histone deacetylase inhibitors by Lakshmaiah, K C, Jacob, Linu A, Aparna, S, Lokanatha, D, Saldanha, Smitha C

“…Epigenetics is the study of heritable alterations in gene expression that are not accompanied by the corresponding change in DNA sequence. Three interlinked…”
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TSC1/2 mutations as markers of response to everolimus in metastatic renal cell carcinoma: A case study by Jacob, Linu, Shafi, Gowhar

“…We report a case of a 67-year-old man with pazopanib-resistant metastatic renal cell carcinoma (mRCC) who showed an exceptional response to everolimus…”
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Extranodal natural-killer/T-cell lymphoma, nasal type: An immunomorphological study from a regional cancer institute in India by Agrawal, Mohit, Champaka, G, Amirtham, Usha, Jacob, Linu, Premalata, C

“…Introduction: Extranodal natural-killer/T-cell lymphoma, nasal type (ENKTL), is a rare, aggressive, predominantly extranodal non-Hodgkin lymphoma (NHL) of…”
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Pro-oncogenic, intra host viral quasispecies in Diffuse large B cell lymphoma patients with occult Hepatitis B Virus infection by Sinha, Mahua, Sundar, Keerthana, Premalata, C. S., Asati, Vikas, Murali, Alka, Bajpai, Akhilesh Kumar, Davuluri, Sravanthi, Acharya, Kshitish K., Lakshmaiah, K. C., Babu K., Govind, Jacob, Linu A., Nandan, Dharam, Velayutham, Dinesh, Datta, Sibnarayan, Jayshree, R. S.

“…Non Hodgkin lymphoma, predominantly Diffuse Large B-cell Lymphoma (DLBCL) has been reported to have a significant association with Hepatitis B virus (HBV). We…”
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Clinicopathological Evaluation of Patients with Hormone Receptor–Positive HER2-Negative Metastatic Breast Cancer Progressing on Endocrine Treatment: A Real-World Retrospective Study from a Regional Cancer Center by Shanthala, S., Amirtham, Usha, Lokesh, K. N., Jacob, Linu, Babu, Govinda

“…Metastatic breast cancer (MBC) is an incurable disease with the primary aim of treatment being the improvement of the patient's quality of life and the delay…”
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Clinico-Pathological Significance and Prognostic Impact of Various PML RARA Transcripts on Outcomes in Acute Promyelocytic Myeloid Leukemia (APML) Treated with Single Agent Arsenic Trioxide(ATO)- Insights from a Tertiary Cancer Center in South India by Sindhusha, K, C Saldanha, Smitha, Abraham Jacob, Linu, Suresh Babu, M.C., Lokesh, K. N., Rudresha, A. H., Rajeev, L. K.

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Rare Case of Isolated Dural Marginal Zone Lymphoma by Babu, MC Suresh, Hassan, Syed Adil, Premalata, Chennagiri S, Lokanatha, D, Jacob, Linu Abraham, Lokesh, NK, Rudresha, HA, Rajeev, KL, Saldanha, Smitha, Thottian, Antony George Francis

“…PCNSL accounts for <1% of all non-Hodgkin's lymphoma cases and approximately 4% of newly diagnosed primary CNS tumors. Answer Diffuse large B-cell lymphoma…”
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BRCA1 expression, its correlation with clinicopathological features, and response to neoadjuvant chemotherapy in high‐grade serous ovarian cancer by Patil, Akkamahadevi, Patil, Sharada, Anupama, C. E., Rajarajan, Savitha, Nimbalkar, Vidya P., Amirtham, Usha, Champaka, G., Suma, M. N., Patil, Geetha V., Nargund, Ashwini, Pallavi, V. R., Jacob, Linu, Premalatha, C. S., Prabhu, Jyothi S.

“…Aim In high‐grade serous ovarian cancers (HG‐SOC), BRCA1 mutation is one of the predominant mutations reported by various studies. However, the non‐mutational…”
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Study of Biomarker Discordance between Primary and Recurrent Sites and its Clinical Implications in Metastatic Breast Cancer : A Single Institutional Study from India by Shanthala, S., Amirtham, Usha, Gopal, Champaka, N., Suma M., Jacob, Linu, Babu, Govinda

“…Immunophenotypic discordance of receptors between primary and metastatic sites significantly impacts treatment outcomes. Current international guidelines…”
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Metastatic hormone receptor-positive breast cancer in CDK 4/6 era: An outcome audit by Lakkavalli, Rajeev, Pehalajani, Jitendra, Tirumala, Venkatesh, Babu, Govind, Loknatha, Dassappa, Jacob, Linu, Babu, Suresh, Rudresha, A, Kadabur, Lokesh, Saldanha, Smitha, Giri, G

“…Background: The treatment landscape of metastatic hormone receptor (HR) positive breast cancer has been changed in recent years. Availability of CDK 4/6…”
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Symptomatic orbital metastasis as an initial presentation of adenocarcinoma lung: A case report and review of literature by Patidar, Yaman, Saldhana, Smitha C, Babu, M C Suresh, Jacob, Linu Abraham, Rudresh, A H, Lokesh, K N, Rajeev, L K

“…Orbital metastasis is a rare entity in oncology. With increasing awareness and advancement, patients with initial ocular presentation can be diagnosed and…”
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Unmasking Infection Risks in Multiple Myeloma: Insights from a Retrospective Analysis by Jacob, Linu Abraham, Choudhary, Sabeena K., Babu, M. C. Suresh, K N, Lokesh, Rudresha, A. H., Rajeev, L. K., Saldanha, Smitha C., Hegde, Anup, B M, Vivek

“…Multiple myeloma (MM) has witnessed significant therapeutic advancements through the introduction of proteasome inhibitors and immunomodulators, leading to…”
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Primary mucinous carcinomas of the lung: Clinical characteristics and treatment outcomes by Rajeev, L, Thottian, Antony, Amirtham, Usha, Lokanatha, D, Jacob, Linu, Babu, M, Lokesh, K, Rudresha, A, Saldanha, Smitha, Hassan, Syed

“…Introduction: Invasive mucinous adenocarcinoma (IMA) of the lung is a distinct histologic variant of adenocarcinomas comprising about 2%-10% of lung…”
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Clinical Profile and Outcome of Adult Classical Hodgkin’s Lymphoma: Real World Single Centre Experience by Jacob, Linu Abraham, Begum, Tarjina, Halder, Arkoprovo, Babu, M. C. Suresh, Lokesh, K. N., Rudresha, A. H., Rajeev, L. K., Saldanha, Smitha C.

“…Hodgkin’s lymphoma treatment outcomes have been the true success story of modern medicine. Various data from western as well as Indian studies are available…”
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Induction chemotherapy in locoregionally advanced nasopharyngeal carcinoma in adults: Results from a nonendemic region by Lokesh, K, Chaudhuri, Tamojit, Lakshmaiah, K, Babu, K, Lokanatha, D, Jacob, Linu, Suresh Babu, M, Rudresha, A, Rajeev, L

“…BACKGROUND: Recently published prospective clinical trials and two meta-analyses have shown that addition of induction chemotherapy (IC) to concurrent…”
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Comparison Between CHOP and DAEPOCH with or Without Rituximab in Adult High Grade B Cell Lymphoma, Not Otherwise Specified; A Retrospective Study From a Tertiary Cancer Hospital in South India by Moharana, Lalatendu, Dasappa, Lokanatha, Babu, Suresh, Lokesh, K. N., Rudresh, Ah, Rajeev, L. K., Saldanha, Smitha, Sharma, Kanika, Jacob, Linu Abraham

“…Lymphoma that on morphology appear blastoid or intermediate between DLBCL and BL but who lack myc and bcl-2 and/or bcl-6 rearrangements are grouped under high…”
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Mortality Audit of Cancer Patients in the Department of Medical Oncology at a Tertiary Cancer Care Centre in South India by Choudhary, Akansha, Jacob, Linu A, Babu, Suresh, K N, Lokesh, A H, Rudresha, L K, Rajeev, Saldanha, Smitha, Begum, Tarjina

“…Considerable advances in the diagnosis and treatment of cancer have made a huge impact on morbidity and mortality from neoplastic diseases. However, cancer…”
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Frequency of Programmed Death Receptor Ligand 1 Expression and Clinicopathological Factors Associated With Metastatic Triple-Negative Breast Cancer at a Tertiary Cancer Care Centre in South India by Babu, Suresh, Choudhary, Akansha, Jacob, Linu, K N, Lokesh, A H, Rudresha, L K, Rajeev, Saldanha, Smitha, Amirtham, Usha, C R, Vijay

“…Purpose Triple-negative breast cancer (TNBC) has a poor outcome compared to other subtypes. Immune checkpoint inhibitors (ICIs) have changed the treatment…”
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Long-Term Outcomes of Reduced High-Risk Clinical Target Volume Margin for Intensity-Modulated Radiotherapy in Locally Advanced Head and Neck Cancers by Tanvir Pasha, Uday Krishna, Rahul Loni, Anil Kumar, Varatharaj Chandraraj, Purushottam Chavan, Ashok Shenoy, Linu Jacob, Thimmaiah Naveen, Lokesh Vishwanath

“…Background: Long-term outcomes of intensity modulated radiotherapy with reduced high-risk clinical target volume (HRCTV) margin for radical chemoradiation of…”
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Epidemiology and outcomes of nasopharyngeal carcinoma: Experience from a regional cancer center in Southern India by Haleshappa, Rudresha Antapura, Thanky, Aditi Harsh, Kuntegowdanahalli, Lakshmaiah, Kanakasetty, Govind Babu, Dasappa, Lokanatha, Jacob, Linu

“…Abstract Context: Nasopharyngeal carcinoma (NPC) is a rare head and neck cancer with significant geographical variation. There are limited data on epidemiology…”
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