Search Results - "Linta, Leonhard"
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A Comparative View on Human Somatic Cell Sources for iPSC Generation
Published in Stem Cells International (01-01-2014)“…The breakthrough of reprogramming human somatic cells was achieved in 2006 by the work of Yamanaka and Takahashi. From this point, fibroblasts are the most…”
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Cellular Zinc Homeostasis Contributes to Neuronal Differentiation in Human Induced Pluripotent Stem Cells
Published in Neural plasticity (01-01-2016)“…Disturbances in neuronal differentiation and function are an underlying factor of many brain disorders. Zinc homeostasis and signaling are important mediators…”
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A Dynamic Role of TBX3 in the Pluripotency Circuitry
Published in Stem cell reports (08-12-2015)“…Pluripotency represents a cell state comprising a fine-tuned pattern of transcription factor activity required for embryonic stem cell (ESC) self-renewal. TBX3…”
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4
An SK3 channel/nWASP/Abi-1 complex is involved in early neurogenesis
Published in PloS one (25-03-2011)“…The stabilization or regulated reorganization of the actin cytoskeleton is essential for cellular structure and function. Recently, we could show that the…”
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Major Tegument Protein pp65 of Human Cytomegalovirus Is Required for the Incorporation of pUL69 and pUL97 into the Virus Particle and for Viral Growth in Macrophages
Published in Journal of Virology (01-03-2009)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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TBX3 Knockdown Decreases Reprogramming Efficiency of Human Cells
Published in Stem cells international (01-01-2016)“…TBX3 is a member of the T-box transcription factor family and is involved in the core pluripotency network. Despite this role in the pluripotency network, its…”
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The dynactin p150 subunit: cell biology studies of sequence changes found in ALS/MND and Parkinsonian Syndromes
Published in Journal of Neural Transmission (01-05-2013)“…The dynactin p150glued subunit, encoded by the gene DCTN1 is part of the dynein–dynactin motor protein complex responsible for retrograde axonal transport…”
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Definitive Endoderm Formation from Plucked Human Hair-Derived Induced Pluripotent Stem Cells and SK Channel Regulation
Published in Stem Cells International (01-01-2013)“…Pluripotent stem cells present an extraordinary powerful tool to investigate embryonic development in humans. Essentially, they provide a unique platform for…”
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Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150Glued
Published in Cell and tissue research (01-10-2012)“…The dynactin p150 Glued subunit, encoded by the gene DCTN1 , is part of the dynein-dynactin motor protein complex responsible for retrograde axonal transport…”
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Microarray-Based Comparisons of Ion Channel Expression Patterns: Human Keratinocytes to Reprogrammed hiPSCs to Differentiated Neuronal and Cardiac Progeny
Published in Stem Cells International (01-01-2013)“…Ion channels are involved in a large variety of cellular processes including stem cell differentiation. Numerous families of ion channels are present in the…”
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The Potential of iPS Cells in Synucleinopathy Research
Published in Stem Cells International (01-01-2012)“…α-synuclein is a protein involved in the pathogenesis of several so-called synucleinopathies including Parkinson's disease. A variety of models have been so…”
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An Inducible Expression System of the Calcium-Activated Potassium Channel 4 to Study the Differential Impact on Embryonic Stem Cells
Published in Stem cells international (01-01-2011)“…Rationale. The family of calcium-activated potassium channels consists of four members with varying biological functions and conductances. Besides membrane…”
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13
Zinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3
Published in Scientific reports (27-03-2017)“…Phelan McDermid Syndrome (PMDS) is a genetic disorder characterized by features of Autism spectrum disorders. Similar to reports of Zn deficiency in autistic…”
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14
A Fresh Look on T-Box Factor Action in Early Embryogenesis (T-Box Factors in Early Development)
Published in Stem cells and development (15-08-2015)“…T-Box transcription factors are expressed throughout the gestational period and coordinate a variety of embryonic events that enable proper development, from…”
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15
Reprogramming to pluripotency does not require transition through a primitive streak-like state
Published in Scientific reports (29-11-2017)“…Pluripotency can be induced in vitro from adult somatic mammalian cells by enforced expression of defined transcription factors regulating and initiating the…”
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Rat embryonic fibroblasts improve reprogramming of human keratinocytes into induced pluripotent stem cells
Published in Stem cells and development (10-04-2012)“…Patient-specific human induced pluripotent stem (hiPS) cells not only provide a promising tool for cellular disease models in general, but also open up the…”
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Developmental and Functional Nature of Human iPSC Derived Motoneurons
Published in Stem cell reviews (01-08-2013)Get full text
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Calcium activated potassium channel expression during human iPS cell-derived neurogenesis
Published in Annals of anatomy (01-07-2013)“…The family of calcium activated potassium channels of low and intermediate conductance, known as SK channels, consists of four members (SK1–4). These channels…”
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Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit p150(Glued)
Published in Cell and tissue research (01-10-2012)“…The dynactin p150(Glued) subunit, encoded by the gene DCTN1, is part of the dynein-dynactin motor protein complex responsible for retrograde axonal transport…”
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20
Tubulin-binding cofactor B is a direct interaction partner of the dynactin subunit [p150.sup.Glued]
Published in Cell and tissue research (01-10-2012)“…The dynactin [p150.sup.Glued] subunit, encoded by the gene DCTN1, is part of the dynein-dynactin motor protein complex responsible for retrograde axonal…”
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