Search Results - "Linnekamp, Janneke F."

Colorectal cancer heterogeneity and targeted therapy: a case for molecular disease subtypes by Linnekamp, Janneke F, Wang, Xin, Medema, Jan Paul, Vermeulen, Louis

“…Personalized cancer medicine is becoming increasingly important in colorectal cancer treatment. Especially for targeted therapies, large variations between…”
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TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype by Fessler, Evelyn, Drost, Jarno, van Hooff, Sander R, Linnekamp, Janneke F, Wang, Xin, Jansen, Marnix, De Sousa E Melo, Felipe, Prasetyanti, Pramudita R, IJspeert, Joep EG, Franitza, Marek, Nürnberg, Peter, van Noesel, Carel JM, Dekker, Evelien, Vermeulen, Louis, Clevers, Hans, Medema, Jan Paul

“…The heterogeneous nature of colorectal cancer (CRC) complicates prognosis and is suggested to be a determining factor in the efficacy of adjuvant therapy for…”
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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models by Linnekamp, Janneke F., Hooff, Sander R. van, Prasetyanti, Pramudita R., Kandimalla, Raju, Buikhuisen, Joyce Y., Fessler, Evelyn, Ramesh, Prashanthi, Lee, Kelly A. S. T., Bochove, Grehor G. W., de Jong, Johan H., Cameron, Kate, Leersum, Ronald van, Rodermond, Hans M., Franitza, Marek, Nürnberg, Peter, Mangiapane, Laura R., Wang, Xin, Clevers, Hans, Vermeulen, Louis, Stassi, Giorgio, Medema, Jan Paul

“…Colorectal cancer (CRC) is a highly heterogeneous disease both from a molecular and clinical perspective. Several distinct molecular entities, such as…”
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Loss of KCNQ1 expression in stage II and stage III colon cancer is a strong prognostic factor for disease recurrence by den Uil, Sjoerd H, Coupé, Veerle M H, Linnekamp, Janneke F, van den Broek, Evert, Goos, Jeroen A C M, Delis-van Diemen, Pien M, Belt, Eric J Th, van Grieken, Nicole C T, Scott, Patricia M, Vermeulen, Louis, Medema, Jan Paul, Bril, Herman, Stockmann, Hein B A C, Cormier, Robert T, Meijer, Gerrit A, Fijneman, Remond J A

“…Background: Colorectal cancer (CRC) is the third most common cancer worldwide. Accurately identifying stage II CRC patients at risk for recurrence is an unmet…”
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Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models by Linnekamp, Janneke F., Hooff, Sander R. van, Prasetyanti, Pramudita R., Kandimalla, Raju, Buikhuisen, Joyce Y., Fessler, Evelyn, Ramesh, Prashanthi, Lee, Kelly A. S. T., Bochove, Grehor G. W., de Jong, Johan H., Cameron, Kate, Leersum, Ronald van, Rodermond, Hans M., Franitza, Marek, Nürnberg, Peter, Mangiapane, Laura R., Wang, Xin, Clevers, Hans, Vermeulen, Louis, Stassi, Giorgio, Medema, Jan Paul

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Pre-Operative Decitabine in Colon Cancer Patients: Analyses on WNT Target Methylation and Expression by Linnekamp, Janneke F., Kandimalla, Raju, Fessler, Evelyn, de Jong, Joan H., Rodermond, Hans M., van Bochove, Gregor G. W., The, Frans O., Punt, Cornelis J. A., Bemelman, Willem A., van de Ven, Anthony W. H., Tanis, Pieter J., Kemper, Elles M., Koens, Lianne, Dekker, Evelien, Vermeulen, Louis, van Laarhoven, Hanneke W. M., Medema, Jan Paul

“…DNA hypermethylation is common in colon cancer. Previously, we have shown that methylation of WNT target genes predicts poor prognosis in stage II colon…”
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Abstract 3125: KCNQ1 expression is a strong prognostic biomarker for disease recurrence in stage II and III colon cancer by den Uil, Sjoerd H., Coupe, Veerle M.H., Linnekamp, Janneke F., van den Broek, Evert, Goos, Jeroen A.C.M., Delis-van Diemen, Pien M., Belt, Eric J.T., van Grieken, Nicole C.T., Scott, Patricia M., Vermeulen, Louis, Medema, Jan Paul, Bril, Herman, Stockmann, Hein B.A.C., Cormier, Robert T., Meijer, Gerrit A., Fijneman, Remond J.

“…Abstract Background: Colorectal cancer (CRC) is the third most common cancer worldwide. Accurately identifying stage II CRC patients at high risk of recurrence…”
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