Search Results - "Link, Jasmin"
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Constraining the Variability of the Atlantic Meridional Overturning Circulation During the Holocene
Published in Geophysical research letters (28-10-2019)“…There is a converging body of evidence supporting a measurable slowdown of the Atlantic Meridional Overturning Circulation (AMOC) as climate warms and Northern…”
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Extracting foraminiferal seawater Nd isotope signatures from bulk deep sea sediment by chemical leaching
Published in Chemical geology (07-11-2016)“…The seawater radiogenic neodymium (143Nd/144Nd) isotope signature is an invaluable tool for the reconstruction of past deep water provenance. Sedimentary…”
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On exposure, vulnerability and violence: Spatial distribution of risk factors for climate change and violent conflict across Kenya and Uganda
Published in Political geography (01-11-2014)“…Recent studies discuss the link between climate change and violent conflict, especially for East Africa. While there is extensive literature on the question…”
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A randomised Phase IIa trial of amine oxidase copper-containing 3 (AOC3) inhibitor BI 1467335 in adults with non-alcoholic steatohepatitis
Published in Nature communications (06-11-2023)“…Non-alcoholic steatohepatitis (NASH) is a progressive, inflammatory liver disease with no approved pharmacological treatment. This Phase IIa, double-blind,…”
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The effect of BI 409306 on heart rate in healthy volunteers: a randomised, double-blind, placebo-controlled, crossover study
Published in European journal of clinical pharmacology (01-05-2022)“…Purpose The potent, selective phosphodiesterase-9A inhibitor BI 409306 may be beneficial for patients with attenuated psychosis syndrome and could prevent…”
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THE NEXUS OF CLIMATE CHANGE, LAND USE, AND CONFLICT: Complex Human–Environment Interactions in Northern Africa
Published in Bulletin of the American Meteorological Society (01-09-2015)“…According to the Fifth Assessment Report (AR5) of the Intergovernmental Panel on Climate Change (IPCC), estimates of possible precipitation changes in northern…”
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Pharmacokinetics and Pharmacodynamics of Twice Daily and Once Daily Regimens of Empagliflozin in Healthy Subjects
Published in Clinical therapeutics (01-08-2015)“…Abstract Purpose This study was undertaken to compare the steady-state pharmacokinetic and pharmacodynamic properties of empagliflozin 5 mg twice daily (BID)…”
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The resilience and sensitivity of Northeast Atlantic deep water εNd to overprinting by detrital fluxes over the past 30,000 years
Published in Geochimica et cosmochimica acta (15-01-2019)“…The neodymium isotope proxy has become a valuable tool for the reconstruction of past ocean water mass provenance and mixing. For its accurate application,…”
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Deep-ocean circulation in the North Atlantic during the Plio-Pleistocene intensification of Northern Hemisphere Glaciation (~2.65–2.4 Ma)
Published in Marine micropaleontology (01-05-2021)“…Through transporting heat around the world and thereby regulating global climate, ocean circulation is an integral part of Earth's climate system that likely…”
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[P3–014]: INVESTIGATION OF PHARMACOKINETIC DRUG‐DRUG INTERACTION FOLLOWING ORAL ADMINISTRATION OF BI 409306 AND DONEPEZIL IN HEALTHY SUBJECTS
Published in Alzheimer's & dementia (01-07-2017)Get full text
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Pharmacokinetics of fixed-dose combinations of empagliflozin/metformin compared with individual tablets in healthy subjects
Published in International journal of clinical pharmacology and therapeutics (01-04-2016)“…To compare the pharmacokinetics of fixed-dose combination (FDC) tablets of empagliflozin/metformin with individual tablets taken together. In 3 randomized,…”
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Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor
Published in European journal of drug metabolism and pharmacokinetics (01-01-2022)“…Background and Objective Increased glycine availability at the synaptic cleft may enhance N -methyl-D-aspartate receptor signalling and provide a promising…”
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INVESTIGATION OF PHARMACOKINETIC DRUG-DRUG INTERACTION FOLLOWING ORAL ADMINISTRATION OF BI 409306 AND DONEPEZIL IN HEALTHY SUBJECTS
Published in Alzheimer's & dementia (01-07-2017)Get full text
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