Search Results - "Link, Daniel"

Gasdermin D mediates the pathogenesis of neonatal-onset multisystem inflammatory disease in mice by Xiao, Jianqiu, Wang, Chun, Yao, Juo-Chin, Alippe, Yael, Xu, Canxin, Kress, Dustin, Civitelli, Roberto, Abu-Amer, Yousef, Kanneganti, Thirumala-Devi, Link, Daniel C, Mbalaviele, Gabriel

“…Mutated NLRP3 assembles a hyperactive inflammasome, which causes excessive secretion of interleukin (IL)-1β and IL-18 and, ultimately, a spectrum of…”
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Football-specific validity of TRACAB's optical video tracking systems by Linke, Daniel, Link, Daniel, Lames, Martin

“…The present study aimed to validate and compare the football-specific measurement accuracy of two optical tracking systems engineered by TRACAB. The "Gen4"…”
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Validation of electronic performance and tracking systems EPTS under field conditions by Linke, Daniel, Link, Daniel, Lames, Martin

“…The purpose of this study was to assess the measurement accuracy of the most commonly used tracking technologies in professional team sports (i.e.,…”
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The hematopoietic stem cell niche in homeostasis and disease by Calvi, Laura M., Link, Daniel C.

“…The bone marrow microenvironment contains a heterogeneous population of stromal cells organized into niches that support hematopoietic stem cells (HSCs) and…”
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Individual ball possession in soccer by Link, Daniel, Hoernig, Martin

“…This paper describes models for detecting individual and team ball possession in soccer based on position data. The types of ball possession are classified as…”
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Targeting of Mesenchymal Stromal Cells by Cre‐Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells by Zhang, Jingzhu, Link, Daniel C

“…ABSTRACT The targeting specificity of tissue‐specific Cre‐recombinase transgenes is a key to interpreting phenotypes associated with their use. The Ocn‐Cre and…”
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Clonal hematopoiesis and risk for hematologic malignancy by Warren, Julia T., Link, Daniel C.

“…Clonal hematopoiesis (CH) is common in older persons and is associated with an increased risk of hematologic cancer. Here, we review studies establishing an…”
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Regulation of hematopoietic stem cells by bone marrow stromal cells by Anthony, Bryan A, Link, Daniel C

“…Highlights • Stromal cell populations in the bone marrow microenvironment regulate hematopoiesis. • Current evidence supports a perivascular HSC niche. •…”
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Mechanisms of leukemic transformation in congenital neutropenia by Link, Daniel C

“…PURPOSE OF REVIEWThe development of a myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) in patients with congenital neutropenia is now the major…”
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A Wnt-mediated transformation of the bone marrow stromal cell identity orchestrates skeletal regeneration by Matsushita, Yuki, Nagata, Mizuki, Kozloff, Kenneth M., Welch, Joshua D., Mizuhashi, Koji, Tokavanich, Nicha, Hallett, Shawn A., Link, Daniel C., Nagasawa, Takashi, Ono, Wanida, Ono, Noriaki

“…Bone marrow stromal cells (BMSCs) are versatile mesenchymal cell populations underpinning the major functions of the skeleton, a majority of which adjoin…”
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Shaping clonal hematopoiesis by Link, Daniel C.

“…In this issue of Blood , Eskelund et al characterize clonal hematopoiesis in serial samples from persons with mantle cell lymphoma (MCL) undergoing frontline…”
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Real Time Quantification of Dangerousity in Football Using Spatiotemporal Tracking Data by Link, Daniel, Lang, Steffen, Seidenschwarz, Philipp

“…This study describes an approach to quantification of attacking performance in football. Our procedure determines a quantitative representation of the…”
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CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance by Greenbaum, Adam, Hsu, Yen-Michael S., Day, Ryan B., Schuettpelz, Laura G., Christopher, Matthew J., Borgerding, Joshua N., Nagasawa, Takashi, Link, Daniel C.

“…Targeted deletion of the chemokine Cxcl12 in different bone marrow stromal cell populations shows that distinct niches exist in the bone marrow for…”
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CXCR2 and CXCR4 antagonistically regulate neutrophil trafficking from murine bone marrow by Eash, Kyle J, Greenbaum, Adam M, Gopalan, Priya K, Link, Daniel C

“…Neutrophils are a major component of the innate immune response. Their homeostasis is maintained, in part, by the regulated release of neutrophils from the…”
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Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells by Xiao, Jianqiu, Wang, Chun, Yao, Juo-Chin, Alippe, Yael, Yang, Tong, Kress, Dustin, Sun, Kai, Kostecki, Kourtney L, Monahan, Joseph B, Veis, Deborah J, Abu-Amer, Yousef, Link, Daniel C, Mbalaviele, Gabriel

“…Radiotherapy is a commonly used conditioning regimen for bone marrow transplantation (BMT). Cytotoxicity limits the use of this life-saving therapy, but the…”
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Expression of the G-CSF receptor in monocytic cells is sufficient to mediate hematopoietic progenitor mobilization by G-CSF in mice by Christopher, Matthew J, Rao, Mahil, Liu, Fulu, Woloszynek, Jill R, Link, Daniel C

“…Granulocyte colony-stimulating factor (G-CSF), the prototypical mobilizing cytokine, induces hematopoietic stem and progenitor cell (HSPC) mobilization from…”
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Peroxisomal Lipid Synthesis Regulates Inflammation by Sustaining Neutrophil Membrane Phospholipid Composition and Viability by Lodhi, Irfan J., Wei, Xiaochao, Yin, Li, Feng, Chu, Adak, Sangeeta, Abou-Ezzi, Grazia, Hsu, Fong-Fu, Link, Daniel C., Semenkovich, Clay F.

“…Fatty acid synthase (FAS) is altered in metabolic disorders and cancer. Conventional FAS null mice die in utero, so effects of whole-body inhibition of…”
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Organ-on-a-chip model of vascularized human bone marrow niches by Glaser, Drew E., Curtis, Matthew B., Sariano, Peter A., Rollins, Zachary A., Shergill, Bhupinder S., Anand, Aravind, Deely, Alyssa M., Shirure, Venktesh S., Anderson, Leif, Lowen, Jeremy M., Ng, Natalie R., Weilbaecher, Katherine, Link, Daniel C., George, Steven C.

“…Bone marrow niches (endosteal and perivascular) play important roles in both normal bone marrow function and pathological processes such as cancer cell…”
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Age-related mutations associated with clonal hematopoietic expansion and malignancies by Xie, Mingchao, Lu, Charles, Wang, Jiayin, McLellan, Michael D, Johnson, Kimberly J, Wendl, Michael C, McMichael, Joshua F, Schmidt, Heather K, Yellapantula, Venkata, Miller, Christopher A, Ozenberger, Bradley A, Welch, John S, Link, Daniel C, Walter, Matthew J, Mardis, Elaine R, Dipersio, John F, Chen, Feng, Wilson, Richard K, Ley, Timothy J, Ding, Li

“…Systematic analysis of cancer-associated mutations in the blood cells of healthy individuals. Several genetic alterations characteristic of leukemia and…”
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Finding the gap: An empirical study of the most effective shots in elite goalball by Link, Daniel, Weber, Christoph

“…This research identifies which shots types in goalball are most likely to lead to a goal and herby provides background information for improving training and…”
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