Search Results - "Liniker, Elizabeth"

High response rate to PD-1 blockade in desmoplastic melanomas by Eroglu, Zeynep, Zaretsky, Jesse M., Hu-Lieskovan, Siwen, Kim, Dae Won, Algazi, Alain, Johnson, Douglas B., Liniker, Elizabeth, Ben Kong, Munhoz, Rodrigo, Rapisuwon, Suthee, Gherardini, Pier Federico, Chmielowski, Bartosz, Wang, Xiaoyan, Shintaku, I. Peter, Wei, Cody, Sosman, Jeffrey A., Joseph, Richard W., Postow, Michael A., Carlino, Matteo S., Hwu, Wen-Jen, Scolyer, Richard A., Messina, Jane, Cochran, Alistair J., Long, Georgina V., Ribas, Antoni

“…Immune checkpoint blockade with anti-PD-1 or anti-PD-L1 agents produces a high response rate in patients with desmoplastic melanoma. Highly sensitive skin…”
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Dynamic Changes in PD-L1 Expression and Immune Infiltrates Early During Treatment Predict Response to PD-1 Blockade in Melanoma by Vilain, Ricardo E, Menzies, Alexander M, Wilmott, James S, Kakavand, Hojabr, Madore, Jason, Guminski, Alexander, Liniker, Elizabeth, Kong, Benjamin Y, Cooper, Adam J, Howle, Julie R, Saw, Robyn P M, Jakrot, Valerie, Lo, Serigne, Thompson, John F, Carlino, Matteo S, Kefford, Richard F, Long, Georgina V, Scolyer, Richard A

“…Disruption of PD-L1/cytotoxic T-cell PD-1 signaling by immune checkpoint inhibitors improves survival in cancer patients. This study sought to identify changes…”
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Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance by Shimamura, Takeshi, Li, Danan, Ji, Hongbin, Haringsma, Henry J, Liniker, Elizabeth, Borgman, Christa L, Lowell, April M, Minami, Yuko, McNamara, Kate, Perera, Samanthi A, Zaghlul, Sara, Thomas, Roman K, Greulich, Heidi, Kobayashi, Susumu, Chirieac, Lucian R, Padera, Robert F, Kubo, Shigeto, Takahashi, Masaya, Tenen, Daniel G, Meyerson, Matthew, Wong, Kwok-Kin, Shapiro, Geoffrey I

“…The epidermal growth factor receptor (EGFR) secondary kinase domain T790M non-small cell lung cancer (NSCLC) mutation enhances receptor catalytic activity and…”
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p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress by Thomas, Sally E., Malzer, Elke, Ordóñez, Adriana, Dalton, Lucy E., van ′t Wout, Emily F.A., Liniker, Elizabeth, Crowther, Damian C., Lomas, David A., Marciniak, Stefan J.

“…Cell cycle checkpoints ensure that proliferation occurs only under permissive conditions, but their role in linking nutrient availability to cell division is…”
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Endoplasmic Reticulum Stress in Malignancy by Clarke, Hanna J., Chambers, Joseph E., Liniker, Elizabeth, Marciniak, Stefan J.

“…The combination of relative nutrient deprivation and dysregulation of protein synthesis make malignant cells especially prone to protein misfolding…”
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Residual FDG-PET metabolic activity in metastatic melanoma patients with prolonged response to anti-PD-1 therapy by Kong, Benjamin Y., Menzies, Alexander M., Saunders, Catherine A. B., Liniker, Elizabeth, Ramanujam, Sangeetha, Guminski, Alex, Kefford, Richard F., Long, Georgina V., Carlino, Matteo S.

“…Summary 18‐Fluorodeoxyglucose positron emission tomography (FDG‐PET) scans were performed on 27 patients with unresectable stage IIIC or IV melanoma after…”
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Patterns of acquired resistance to anti-PD-1 antibodies in patients with metastatic melanoma (MM) by Lee, Jenny HJ, Cooper, Adam James, Lyle, Megan Kate, Liniker, Elizabeth, Menzies, Alexander M., Kefford, Richard, Long, Georgina V., Carlino, Matteo S.

“…Abstract only…”
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Mo1877 Infliximab for the Treatment of Ipilimumab (anti CTLA-4) and Nivolumab/Pembrolizumab (anti-PD-1) Associated Colitis by Sidhu, Mayenaaz, Mersaides, Antony, Liniker, Elizabeth, Tate, David J, Nagrial, Adnan, Long, Georgina, Sandanayake, Neomal S, Kariyawasam, Viraj C, Carlino, Matteo S, Kwan, Vu

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Analysis of mutational burden and adaptive immune response in desmoplastic melanomas treated with PD-1/L1 inhibitors by Hu-Lieskovan, Siwen, Eroglu, Zeynep, Zaretsky, Jesse Meir, Kim, Dae Won, Algazi, Alain Patrick, Johnson, Douglas Buckner, Liniker, Elizabeth, Kong, Ben, Munhoz, Rodrigo, Rapisuwon, Suthee, Chmielowski, Bartosz, Sosman, Jeffrey Alan, Scolyer, Richard A., Joseph, Richard Wayne, Postow, Michael Andrew, Carlino, Matteo S., Hwu, Wen-Jen, Long, Georgina V., Ribas, Antoni

“…Abstract only 9558 Background: Desmoplastic melanoma (DM) is a rare subtype of melanoma characterized by a dense fibrous stroma, resistance to chemotherapy and…”
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Reply to ‘Comment on ‘Efficacy and toxicity of treatment with the anti-CTLA-4 antibody ipilimumab in patients with metastatic melanoma after prior anti-PD-1 therapy’’ by Bowyer, Samantha, Prithviraj, Prashanth, Lorigan, Paul, Larkin, James, McArthur, Grant, Atkinson, Victoria, Millward, Michael, Khou, Muoi, Diem, Stefan, Ramanujam, Sangeetha, Kong, Ben, Liniker, Elizabeth, Guminski, Alexander, Parente, Phillip, Andrews, Miles C, Parakh, Sagun, Cebon, Jonathan, Long, Georgina V, Carlino, Matteo S, Klein, Oliver

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Response to anti-PD1/PDL1 therapy in patients with metastatic desmoplastic melanoma by Eroglu, Zeynep, Kim, Dae Won, Johnson, Douglas Buckner, Algazi, Alain Patrick, Munhoz, Rodrigo Ramella, Liniker, Elizabeth, Kong, Ben, Khurana, Neharika, Chmielowski, Bartosz, Sosman, Jeffrey Alan, Scolyer, Richard A, Carlino, Matteo S., Postow, Michael Andrew, Hwu, Wen-Jen, Long, Georgina V., Ribas, Antoni

“…Abstract only…”
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Temporary bilateral oculomotor nerve palsy as the sole presenting sign of a pituitary mass by Liniker, Elizabeth, Hyatt, Penny

“…A 65-year-old patient presented with isolated bilateral third nerve palsy. Neuroimaging demonstrated a 2 cm pituitary mass with extension into the cavernous…”
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