Search Results - "Linhart, Heinz"

Comparison of PET imaging with a (68)Ga-labelled PSMA ligand and (18)F-choline-based PET/CT for the diagnosis of recurrent prostate cancer by Afshar-Oromieh, Ali, Zechmann, Christian M, Malcher, Anna, Eder, Matthias, Eisenhut, Michael, Linhart, Heinz G, Holland-Letz, Tim, Hadaschik, Boris A, Giesel, Frederik L, Debus, Jürgen, Haberkorn, Uwe

“…Positron emission tomography (PET) with choline tracers has found widespread use for the diagnosis of prostate cancer (PC). However, choline metabolism is not…”
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The diagnostic value of PET/CT imaging with the (68)Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer by Afshar-Oromieh, Ali, Avtzi, Eleni, Giesel, Frederik L, Holland-Letz, Tim, Linhart, Heinz G, Eder, Matthias, Eisenhut, Michael, Boxler, Silvan, Hadaschik, Boris A, Kratochwil, Clemens, Weichert, Wilko, Kopka, Klaus, Debus, Jürgen, Haberkorn, Uwe

“…Since the introduction of positron emission tomography (PET) imaging with (68)Ga-PSMA-HBED-CC (=(68)Ga-DKFZ-PSMA-11), this method has been regarded as a…”
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Cell-of-Origin DNA Methylation Signatures Are Maintained during Colorectal Carcinogenesis by Bormann, Felix, Rodríguez-Paredes, Manuel, Lasitschka, Felix, Edelmann, Dominic, Musch, Tanja, Benner, Axel, Bergman, Yehudit, Dieter, Sebastian M., Ball, Claudia R., Glimm, Hanno, Linhart, Heinz G., Lyko, Frank

“…Colorectal adenomas are precursor lesions of colorectal cancers and represent clonal amplifications of single cells from colonic crypts. DNA methylation…”
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Dnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencing by Linhart, Heinz G, Lin, Haijiang, Yamada, Yasuhiro, Moran, Eva, Steine, Eveline J, Gokhale, Sumita, Lo, Grace, Cantu, Erika, Ehrich, Mathias, He, Timothy, Meissner, Alex, Jaenisch, Rudolf

“…Increased methylation of CpG islands and silencing of affected target genes is frequently found in human cancer; however, in vivo the question of causality has…”
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Opposing Effects of DNA Hypomethylation on Intestinal and Liver Carcinogenesis by Yamada, Yasuhiro, Jackson-Grusby, Laurie, Linhart, Heinz, Meissner, Alex, Eden, Amir, Lin, Haijiang, Jaenisch, Rudolf

“…Genome-wide DNA hypomethylation and concomitant promoter-specific tumor suppressor gene hypermethylation are among the most common molecular alterations in…”
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Folate Deficiency Induces Genomic Uracil Misincorporation and Hypomethylation But Does Not Increase DNA Point Mutations by Linhart, Heinz G, Troen, Aron, Bell, George W, Cantu, Erika, Chao, Wei–Hsun, Moran, Eva, Steine, Eveline, He, Timothy, Jaenisch, Rudolf

“…Background and Aims Epidemiologic studies have linked nutritional folate deficiency to an increased risk of cancer, but recent trials suggest that folate…”
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Epigenetics and Proteomics Join Transcriptomics in the Quest for Tuberculosis Biomarkers by Esterhuyse, Maria M, Weiner, 3rd, January, Caron, Etienne, Loxton, Andre G, Iannaccone, Marco, Wagman, Chandre, Saikali, Philippe, Stanley, Kim, Wolski, Witold E, Mollenkopf, Hans-Joachim, Schick, Matthias, Aebersold, Ruedi, Linhart, Heinz, Walzl, Gerhard, Kaufmann, Stefan H E

“…An estimated one-third of the world's population is currently latently infected with Mycobacterium tuberculosis. Latent M. tuberculosis infection (LTBI)…”
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Can the battle against tuberculosis gain from epigenetic research? by Esterhuyse, Maria M, Linhart, Heinz G, Kaufmann, Stefan H.E

“…A healthy immune system needs to be highly plastic to cope with host defense and surveillance. What mechanisms provide this plasticity? Considering the threat…”
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Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase by Kronenberg, Golo, Harms, Christoph, Sobol, Robert W, Cardozo-Pelaez, Fernando, Linhart, Heinz, Winter, Benjamin, Balkaya, Mustafa, Gertz, Karen, Gay, Shanna B, Cox, David, Eckart, Sarah, Ahmadi, Michael, Juckel, Georg, Kempermann, Gerd, Hellweg, Rainer, Sohr, Reinhard, Hortnagl, Heide, Wilson, Samuel H, Jaenisch, Rudolf, Endres, Matthias

“…Folate deficiency and resultant increased homocysteine levels have been linked experimentally and epidemiologically with neurodegenerative conditions like…”
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Analysis of conditional gene deletion using probe based Real-Time PCR by Weis, Britta, Schmidt, Joachim, Lyko, Frank, Linhart, Heinz G

“…Conditional gene deletion using Cre-lox recombination is frequently used in mouse genetics; however recombination is frequently incomplete, resulting in a…”
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Suppression of Intestinal Neoplasia by Deletion of Dnmt3b by Lin, Haijiang, Yamada, Yasuhiro, Nguyen, Suzanne, Linhart, Heinz, Jackson-Grusby, Laurie, Meissner, Alexander, Meletis, Konstantinos, Lo, Grace, Jaenisch, Rudolf

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer by Steine, Eveline J, Ehrich, Mathias, Bell, George W, Raj, Arjun, Reddy, Seshamma, van Oudenaarden, Alexander, Jaenisch, Rudolf, Linhart, Heinz G

“…Human cancer cells frequently have regions of their DNA hypermethylated, which results in transcriptional silencing of affected genes and promotion of tumor…”
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The generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver disease by Linhart, Kirsten-Berit, Glassen, Katharina, Peccerella, Teresa, Waldherr, Rüdiger, Linhart, Heinz, Bartsch, Helmut, Seitz, Helmut K.

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Detection of cranial meningiomas: comparison of 68Ga-DOTATOC PET/CT and contrast-enhanced MRI by Afshar-Oromieh, Ali, Giesel, Frederik L., Linhart, Heinz G., Haberkorn, Uwe, Haufe, Sabine, Combs, Stephanie E., Podlesek, Dino, Eisenhut, Michael, Kratochwil, Clemens

“…Purpose PET imaging with somatostatin receptor ligands, such as 68 Ga-DOTATOC, is a well-established method for detection and target volume definition of…”
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Analysis of conditional gene deletion using probe based Real-Time PCR by Weis, Britta, Schmidt, Joachim, Lyko, Frank, Linhart, Heinz G

“…Following publication of this article 1 the authors noticed that an incorrect probe reference was cited on page 3, 4, 5 and 6 ("UP #69, Roche Applied…”
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C/EBPα is Required for Differentiation of White, but not Brown, Adipose Tissue by Linhart, Heinz G., Ishimura-Oka, Kazumi, DeMayo, Franco, Kibe, Tetsuya, Repka, David, Poindexter, Brian, Bick, Roger J., Darlington, Gretchen J.

“…The transcription factor CCAAT enhancer binding protein α (C/EBPα) is expressed at high levels in liver and adipose tissue. Cell culture studies show that…”
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The diagnostic value of PET/CT imaging with the 68Ga-labelled PSMA ligand HBED-CC in the diagnosis of recurrent prostate cancer by Afshar-Oromieh, Ali, Avtzi, Eleni, Giesel, Frederik L., Holland-Letz, Tim, Linhart, Heinz G., Eder, Matthias, Eisenhut, Michael, Boxler, Silvan, Hadaschik, Boris A., Kratochwil, Clemens, Weichert, Wilko, Kopka, Klaus, Debus, Jürgen, Haberkorn, Uwe

“…Purpose Since the introduction of positron emission tomography (PET) imaging with 68 Ga-PSMA-HBED-CC (= 68 Ga-DKFZ-PSMA-11), this method has been regarded as a…”
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Chronic inflammation induces a novel epigenetic program that is conserved in intestinal adenomas and in colorectal cancer by Abu-Remaileh, Monther, Bender, Sebastian, Raddatz, Günter, Ansari, Ihab, Cohen, Daphne, Gutekunst, Julian, Musch, Tanja, Linhart, Heinz, Breiling, Achim, Pikarsky, Eli, Bergman, Yehudit, Lyko, Frank

“…Chronic inflammation represents a major risk factor for tumor formation, but the underlying mechanisms have remained largely unknown. Epigenetic mechanisms can…”
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Abstract 4350: Cell-of-origin differentiation stages define methylation-based subtypes of human colorectal cancer by Bormann, Felix, Rodríguez-Paredes, Manuel, Bergman, Yehudit, Linhart, Heinz G., Lyko, Frank

“…Abstract Introduction: Colorectal cancer accounts for a significant fraction of cancer-related mortalities, but has proven to be surprisingly refractory to…”
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Increased DNA methylation of Dnmt3b targets impairs leukemogenesis by Schulze, Isabell, Rohde, Christian, Scheller-Wendorff, Marina, Bäumer, Nicole, Krause, Annika, Herbst, Friederike, Riemke, Pia, Hebestreit, Katja, Tschanter, Petra, Lin, Qiong, Linhart, Heinz, Godley, Lucy A., Glimm, Hanno, Dugas, Martin, Wagner, Wolfgang, Berdel, Wolfgang E., Rosenbauer, Frank, Müller-Tidow, Carsten

“…The de novo DNA methyltransferases Dnmt3a and Dnmt3b are of crucial importance in hematopoietic stem cells. Dnmt3b has recently been shown to play a role in…”
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