Search Results - "Lingueglia, E."

ASIC2b-dependent Regulation of ASIC3, an Essential Acid-sensing Ion Channel Subunit in Sensory Neurons via the Partner Protein PICK-1 by Deval, Emmanuel, Salinas, Miguel, Baron, Anne, Lingueglia, Eric, Lazdunski, Michel

“…ASIC3, an acid-sensing ion channel subunit expressed essentially in sensory neurons, has been proposed to be involved in pain. We show here for the first time…”
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Canaux ASIC senseurs de l’acidification, lysophosphatidylcholine et douleur chronique by Delanoe, K., Marchand, F., Lingueglia, E., Deval, E.

“…Les ASIC ( Acid-Sensing Ion Channel ) forment une famille de canaux cationiques excitateurs activés par les protons extracellulaires. Ils sont largement…”
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Effects of neuropeptide SF and related peptides on acid sensing ion channel 3 and sensory neuron excitability by Deval, E., Baron, A., Lingueglia, E., Mazarguil, H., Zajac, J.-M., Lazdunski, M.

“…Acid sensing ion channel 3 (ASIC3) is a cation channel gated by extracellular protons. It is highly expressed in sensory neurons, including small nociceptive…”
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Protein Kinase C Stimulates the Acid-sensing Ion Channel ASIC2a via the PDZ Domain-containing Protein PICK1 by Baron, Anne, Deval, Emmanuel, Salinas, Miguel, Lingueglia, Eric, Voilley, Nicolas, Lazdunski, Michel

“…Acid-sensing ion channels (ASICs) are cationic channels activated by extracellular protons. They are expressed in central and sensory neurons where they are…”
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H(+)-gated cation channels by Waldmann, R, Champigny, G, Lingueglia, E, De Weille, J R, Heurteaux, C, Lazdunski, M

“…H(+)-gated cation channels are members of a new family of ionic channels, which includes the epithelial Na+ channel and the FMRFamide-activated Na+ channel…”
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Biochemical analysis of the membrane topology of the amiloride-sensitive Na+ channel by RENARD, S, LINGUEGLIA, E, VOILLEY, N, LAZDUNSKI, M, BARBRY, P

“…A key protein component of the amiloride-sensitive sodium channel has been cloned from rat colon and human lung. It may represent the first member of a new…”
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Different homologous subunits of the amiloride-sensitive Na+ channel are differently regulated by aldosterone by LINGUEGLIA, E, RENARD, S, WALDMANN, R, VOILLEY, N, CHAMPIGNY, G, PLASS, H, LAZDUNSKI, M, BARBRY, P

“…Long term regulation of the amiloride-sensitive Na+ channel activity by steroid hormones occurs via de novo protein synthesis. The messenger level of RCNaCh1,…”
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The Multivalent PDZ Domain-containing Protein CIPP Is a Partner of Acid-sensing Ion Channel 3 in Sensory Neurons by Anzai, Naohiko, Deval, Emmanuel, Schaefer, Lionel, Friend, Valerie, Lazdunski, Michel, Lingueglia, Eric

“…Acid-sensing ion channels (ASICs) are cationic channels activated by extracellular pH. They are present in the brain, where they are thought to participate in…”
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Regulation of expression of the lung amiloride‐sensitive Na+ channel by steroid hormones by Champigny, G., Voilley, N., Lingueglia, E., Friend, V., Barbry, P., Lazdunski, M.

“…Molecular cloning of the amiloride‐sensitive Na+ channel has permitted analysis of the mechanisms of its stimulation by steroids. In rat lung cells in primary…”
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The Lung Amiloride-Sensitive Na+Channel: Biophysical Properties, Pharmacology, Ontogenesis, and Molecular Cloning by Voilley, Nicolas, Lingueglia, Eric, Champigny, Guy, Mattei, Marie-Genevieve, Waldmann, Rainer, Lazdunski, Michel, Barbry, Pascal

“…Water balance in the lung is controlled via active Na+and Cl-transport. Electrophysiological measurements on lung epithelial cells demonstrated the presence of…”
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new member of the amiloride-sensitive sodium channel family in Drosophila melanogaster peripheral nervous system by Darboux, I, Lingueglia, E, Pauron, D, Barbry, P, Lazdunski, M

“…Amiloride sensitivity is a common characteristic of structurally related cationic channels that are associated with a wide range of physiological functions. In…”
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Exploration of the pore structure of a peptide-gated Na+ channel by Poët, Mallorie, Tauc, Michel, Lingueglia, Eric, Cance, Peggy, Poujeol, Philippe, Lazdunski, Michel, Counillon, Laurent

“…The FMRF‐amide‐activated sodium channel (FaNaC), a member of the ENaC/Degenerin family, is a homotetramer, each subunit containing two transmembrane segments…”
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Canaux ASIC senseurs de l’acidification, lysophosphatidylcholine et douleur chronique by Delanoe, K., Marchand, F., Lingueglia, E., Deval, Emmanuel

“…ASICs (Acid-Sensing Ion Channels) constitute a family of excitatory cation channels activated by extracellular protons. They are widely expressed in pain…”
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Lysophosphatidylcholine 16:0 mediates chronic joint pain associated to rheumatic diseases through acid-sensing ion channel 3 by Jacquot, Florian, Khoury, Spiro, Labrum, Bonnie, Delanoe, Kévin, Pidoux, Ludivine, Barbier, Julie, Delay, Lauriane, Bayle, Agathe, Aissouni, Youssef, Barriere, David A., Kultima, Kim, Freyhult, Eva, Hugo, Anders, Kosek, Eva, Ahmed, Aisha S., Jurczak, Alexandra, Lingueglia, Eric, Svensson, Camilla I., Breuil, Véronique, Ferreira, Thierry, Marchand, Fabien, Deval, Emmanuel

“…Rheumatic diseases are often associated to debilitating chronic pain, which remains difficult to treat and requires new therapeutic strategies. We had…”
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Non-acidic activation of pain-related Acid-Sensing Ion Channel 3 by lipids by Marra, Sébastien, Ferru-Clément, Romain, Breuil, Véronique, Delaunay, Anne, Christin, Marine, Friend, Valérie, Sebille, Stéphane, Cognard, Christian, Ferreira, Thierry, Roux, Christian, Euller-Ziegler, Liana, Noel, Jacques, Lingueglia, Eric, Deval, Emmanuel

“…Extracellular pH variations are seen as the principal endogenous signal that triggers activation of Acid‐Sensing Ion Channels (ASICs), which are basically…”
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Douleur et canaux ioniques : une mise à jour importante mais pas encore majeure by Lingueglia, E.

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Human Kidney Amiloride-Binding Protein: cDNA Structure and Functional Expression by Barbry, Pascal, Champe, Mark, Chassande, Olivier, Munemitsu, Susan, Champigny, Guy, Lingueglia, Eric, Maes, Pierrette, Frelin, Christian, Tartar, Andre, Ullrich, Axel, Lazdunski, Michael

“…Phenamil, an analog of amiloride, is a potent blocker of the epithelial Na+channel. It has been used to purify the porcine kidney amiloride-binding protein…”
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Les récepteurs des protons et de la capsaïcine: Contribution à la physiologie et la physiopathologie de la douleur by Lingueglia, E.

“…Résumé: Les structures moléculaires de deux canaux ioniques activés par des ligands et présents dans les terminaisons nerveuses sensorielles nociceptives, le…”
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Molecular biology of the amiloride-sensitive epithelial Na+ channel by Lingueglia, E, Voilley, N, Lazdunski, M, Barbry, P

“…The amiloride-sensitive epithelial Na+ channel is formed by the assembly of three homologous subunits, alpha, beta and gamma. The channel is characterized by…”
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Human ASIC3 channel dynamically adapts its activity to sense the extracellular pH in both acidic and alkaline directions by Delaunay, A., Gasull, X., Salinas, M., Noël, J., Friend, V., Lingueglia, E., Deval, Emmanuel

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